Amorolfine hydrochloride

ChemicalBook > CAS DataBase List > Amorolfine hydrochloride

Amorolfine hydrochloride

Product Name: Amorolfine hydrochloride
CAS No.: 78613-38-4
Chemical Name: Amorolfine hydrochloride
Synonyms: Odenil;Locetar;Curanail;Amorolfine HCI;AMOROLFINE HCL;Ro 14-4767/002;Amorolfine hydrochloride;Amorolfine Hydrochloride >Amorolfine hydrochloride CRS;Amorolfine hydrochloride, >=99%
CBNumber: CB8262394
Molecular Formula: C21H36ClNO
Formula Weight: 353.98
MOL File: 78613-38-4.mol

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Amorolfine hydrochloride Property

Boiling point:: 120 C
storage temp.: room temp
solubility: DMSO: ≥5mg/mL (warmed)
form: powder
color: white to beige
InChIKey: XZKWIPVTHGWDCF-KUZYQSSXSA-N
CAS DataBase Reference: 78613-38-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,N
Risk Statements: 20/21/22-36/37/38-50/53-38-22
Safety Statements: 26-36-61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
HS Code: 29411010

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H411Toxic to aquatic life with long lasting effects

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0283
Product name: Amorolfine hydrochloride
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $140
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0283
Product name: Amorolfine hydrochloride
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $429
Updated: 2024/03/01

TCI Chemical

Product number: A2161
Product name: Amorolfine Hydrochloride
Purity: >98.0%(T)
Packaging: 1g
Price: $238
Updated: 2024/03/01

TCI Chemical

Product number: A2161
Product name: Amorolfine Hydrochloride
Purity: >98.0%(T)
Packaging: 200mg
Price: $79
Updated: 2024/03/01

Cayman Chemical

Product number: 26077
Product name: Amorolfine (hydrochloride)
Purity: ≥98%
Packaging: 100mg
Price: $62
Updated: 2024/03/01

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Amorolfine hydrochloride Chemical Properties,Usage,Production

Description

Amorolfine hydrochloride is the first morpholine antifungal agent useful in the topical treatment of onychomycosis. Mechanistically, it appears to inhibit two stages of the ergosterol biosynthetic pathway, which is necessary for fungal cell viability. Active against a broad spectrum of fungi, amorolfiie hydrochloride is particularly effective against yeasts such as Histoplasma capsulatum, dermatophytes and dematiaceous fungi.

Chemical Properties

Liquid

Originator

Roche (Switzerland)

Uses

Amorolfine hydrochloride has been used as an antifungal agent.

Uses

antihypertensive

Definition

ChEBI: A hydrochloride resulting from the formal reacton of equimolar amounts of hydrogen chloride and amorolfine. An inhibitor of the action of squalene monooxygenase, Delta14 reductase and D7-D8 isomerase and an antifungal ag nt, it is used for the topical treatment of fungal nail and skin infections.

brand name

Loceryl (Hoffmann-LaRoche).

Biochem/physiol Actions

Amorolfine is a broad-based antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts. Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation.

Amorolfine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Amorolfine hydrochloride manufacturers

Hebei Guanlang Biotechnology Co., Ltd.

Product: Amorolfine hydrochloride 78613-38-4
Price: US $1.00/PCS
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2021-05-31

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: Amorolfine hydrochloride 78613-38-4
Price: US $15.00/kg
Min. Order: 1kg
Purity: 99.912%
Supply Ability: 10ton
Release date: 2024-04-24

Hebei Xinsheng New Material Technology Co., LTD.

Product: Amorolfine hydrochloride 78613-38-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 20tons
Release date: 2023-09-04

78613-38-4, Amorolfine hydrochlorideRelated Search:

Moroxydine hydrochloride Moroxydine Amorolfine hydrochloride 1-AdaMantanethylaMine ISOPROPYLHYDRAZINE HYDROCHLORIDE Amorolfine Topotecan hydrochloride Tridemorph Dimethomorph Hydroxylamine hydrochloride Tramadol hydrochloride cis-2,6-Dimethylmorpholine Dimethylmorpholine Sibutramine hydrochloride N-[2-(acetyloxy)propyl]-N-[3-[4-(1,1-diMethylpropyl)phenyl]-2-Methylpropyl]-forMaMide Amorolfine Impurity 6 Amorolfine Impurity 11 4-[3-[4-(1,1-diMethylpropyl)-phenyl]-2-Methylpropyl]-2,6-diMethylMorpholine 4-oxide

AMOROLFINE HCL

Amorolfine HCI

Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride, (2R,6S)-rel-

Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride, cis-

Ro 14-4767/002

(+/-)-cis-2,6-Dimethyl-4-[2-methyl-3-(p-tert-pentylphenyl)propyl]morpholine hydrochloride

Amorolfine hydrochloride

(2R,6S)-rel-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine, hydrochloride (1:1)

(2R,6S)-rel-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride

Amorolfine hydrochloride, >=99%

AMOROLFIN; CURANAIL; LOCERYL; LOCETAR; ODENIL

Curanail

Locetar

Odenil

2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine hydrochloride

Amorolfine for system suitability

(2R,6S)-2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride

Amorolfine Hydrochloride &gt

Amorolfine for system suitability CRS

Amorolfine hydrochloride CRS

cis-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride

2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine

(2R,6S)-rel-2,6-Dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride

Amorolfine hydrochloride USP/EP/BP

Amorolfine HCl (Ro 14-4767/002)

Amorolfine HydrochlorideQ: What is Amorolfine Hydrochloride Q: What is the CAS Number of Amorolfine Hydrochloride Q: What is the storage condition of Amorolfine Hydrochloride Q: What are the applications of Amorolfine Hydrochloride

rel-(2R,6S)-2,6-Dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride (Amorolfine Impurity)

(2S,6R)-2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride

78613-38-4

78163-38-4

C21H35ONHCl

HYTRIN

Antifungal (Topical)

Antifungals for Research and Experimental Use

Biochemistry

78613-38-4