ETHYL 4-PIPERIDONE-3-CARBOXYLATE HYDROCHLORIDE
- Product Name
- ETHYL 4-PIPERIDONE-3-CARBOXYLATE HYDROCHLORIDE
- CAS No.
- 4644-61-5
- Chemical Name
- ETHYL 4-PIPERIDONE-3-CARBOXYLATE HYDROCHLORIDE
- Synonyms
- EthylesterHCl;TIMTEC-BB SBB003473;LABOTEST-BB LT00455216;(+/-)4-oxo-Nipecoticacid;3-CARBETHOXY-4-PIPERIDONE HCL;Ethyl 4-piperidoe-3-carboxylate;3-Ethoxycarbonyl-4-piperidinone;Ethyl-4-piperidone-3-carboxylateHCl;ethyl 4-oxopiperidine-3-carboxylate;3-CARBETHOXY-4-PIPERIDONE HYDROCHLORIDE
- CBNumber
- CB8264631
- Molecular Formula
- C8H14ClNO3
- Formula Weight
- 207.65
- MOL File
- 4644-61-5.mol
ETHYL 4-PIPERIDONE-3-CARBOXYLATE HYDROCHLORIDE Property
- Melting point:
- 169-175 °C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Water Solubility
- Soluble in water
- form
- powder to crystal
- color
- White to Brown
- BRN
- 3711279
- InChI
- InChI=1S/C8H13NO3.ClH/c1-2-12-8(11)6-5-9-4-3-7(6)10;/h6,9H,2-5H2,1H3;1H
- InChIKey
- RTYXWLMQWSFXNI-UHFFFAOYSA-N
- SMILES
- C1(CNCCC1=O)C(=O)OCC.Cl
- CAS DataBase Reference
- 4644-61-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- E0896
- Product name
- Ethyl 4-Oxo-3-piperidinecarboxylate Hydrochloride
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 5g
- Price
- $97
- Updated
- 2025/07/31
- Product number
- E0896
- Product name
- Ethyl 4-Oxo-3-piperidinecarboxylate Hydrochloride
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 25g
- Price
- $387
- Updated
- 2025/07/31
- Product number
- E926215
- Product name
- Ethyl4-piperidone-3-carboxylatehydrochloride
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 449302
- Product name
- Ethyl 4-piperidone-3-carboxylate, HCl
- Packaging
- 100mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- J51492
- Product name
- Ethyl4-piperidone-3-carboxylatehydrochloride
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
ETHYL 4-PIPERIDONE-3-CARBOXYLATE HYDROCHLORIDE Chemical Properties,Usage,Production
Chemical Properties
white to yellow crystalline powder
Uses
Ethyl 4-piperidone-3-carboxylate, HCl
Synthesis
1454-53-1
4644-61-5
General procedure for the synthesis of ethyl piperidin-4-one-3-carboxylate hydrochloride from ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride: in a 50 mL reactor, ethyl N-benzyl-4-oxo-piperidine-3-carboxylate hydrochloride (12 g, 40.29 mmol) and Pd(OH)2/C catalyst (120 mg, 1 wt%) were added. The reaction was stirred for 48 h under 5 bar hydrogen pressure using a dry solvent mixture of dichloromethane and methanol (4:1, v/v) as the reaction medium. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad followed by evaporation of the solvent under reduced pressure to afford 8.3 g of the target product, ethyl piperidin-4-one-3-carboxylate hydrochloride, as a light brown solid in 99% yield.
References
[1] Tetrahedron, 1991, vol. 50, # 2, p. 515 - 528
[2] Tetrahedron Letters, 2012, vol. 53, # 26, p. 3296 - 3300
[3] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 8, p. 1784 - 1796
[4] Archiv der Pharmazie, 2018, vol. 351, # 9,
[5] Patent: CN108586454, 2018, A. Location in patent: Paragraph 0134; 0136; 0137
ETHYL 4-PIPERIDONE-3-CARBOXYLATE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ETHYL 4-PIPERIDONE-3-CARBOXYLATE HYDROCHLORIDE manufacturers
- Product
- ETHYL 4-PIPERIDONE-3-CARBOXYLATE HYDROCHLORIDE 4644-61-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2018-08-09