Methyl 3-aminopropionate hydrochloride
- Product Name
- Methyl 3-aminopropionate hydrochloride
- CAS No.
- 3196-73-4
- Chemical Name
- Methyl 3-aminopropionate hydrochloride
- Synonyms
- β-Alanine methyl ester hydrochloride;METHYL 3-AMINOPROPANOATE HYDROCHLORIDE;BETA-ALANINE METHYL ESTER HYDROCHLORIDE;H-βα-Cetone;H-β-Ala-Ome;-Ala-pNA HBr;-Ala-OMe.HCl;β-Ala-Ome.HCl;H-β-Ala-Ome.HCl
- CBNumber
- CB5368763
- Molecular Formula
- C4H10ClNO2
- Formula Weight
- 139.58
- MOL File
- 3196-73-4.mol
Methyl 3-aminopropionate hydrochloride Property
- Melting point:
- 103-105 °C
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Crystalline Powder
- color
- White to off-white
- Sensitive
- Hygroscopic
- BRN
- 3556748
- InChI
- InChI=1S/C4H9NO2.ClH/c1-7-4(6)2-3-5;/h2-3,5H2,1H3;1H
- InChIKey
- XPGRZDJXVKFLHQ-UHFFFAOYSA-N
- SMILES
- C(=O)(OC)CCN.Cl
- CAS DataBase Reference
- 3196-73-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 05210
- Product name
- β-Alanine methyl ester hydrochloride
- Purity
- ≥98.0% (AT)
- Packaging
- 10g
- Price
- $147
- Updated
- 2023/06/20
- Product number
- A2603
- Product name
- β-Alanine Methyl Ester Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $45
- Updated
- 2025/07/31
- Product number
- A2603
- Product name
- β-Alanine Methyl Ester Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $155
- Updated
- 2025/07/31
- Product number
- 277367
- Product name
- H-beta-
- Packaging
- 500mg
- Price
- $360
- Updated
- 2021/12/16
- Product number
- 277366
- Product name
- H-beta-
- Packaging
- 500mg
- Price
- $375
- Updated
- 2021/12/16
Methyl 3-aminopropionate hydrochloride Chemical Properties,Usage,Production
Chemical Properties
white to off-white crystalline powder
Uses
β-Alanine Methyl Ester is an intermediate in the synthesis of Trichostatin A (T774710) and Trapoxin B as histone deacetylase inhibitors.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
67-56-1
107-95-9
3196-73-4
Under ice bath conditions, 60 mL of methanol was added to a 100 mL round-bottom flask, followed by the slow dropwise addition of 4 mL of sulfoxide chloride (SOCl2) through a constant-pressure dropping funnel (with a desiccant tube at the top), and the resulting off-gas was absorbed with NaOH solution. After stirring the reaction mixture for 1 h, 8 mmol of β-alanine was added and stirring was continued for 30 min at room temperature. Subsequently, the reaction system was warmed up to 66 °C and refluxed for 6 hours. The reaction process was monitored by thin-layer chromatography (TLC) using a 2% ethanol solution of ninhydrin as a color developer until the raw material spot disappeared. Upon completion of the reaction, the solvent was removed by distillation to afford methyl 3-aminopropionate hydrochloride in 100% yield.
References
[1] European Journal of Organic Chemistry, 2012, # 29, p. 5774 - 5788,15
[2] European Journal of Organic Chemistry, 2012, # 29, p. 5774 - 5788
[3] Patent: US2014/206741, 2014, A1. Location in patent: Paragraph 0016
[4] European Journal of Medicinal Chemistry, 2018, vol. 154, p. 44 - 59
[5] Journal of Organic Chemistry, 1991, vol. 56, # 7, p. 2553 - 2557
Methyl 3-aminopropionate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 3-aminopropionate hydrochloride Suppliers
- Tel
- 027-65528353 13554206703
- HBJC3279834739@foxmail.com
- Country
- China
- ProdList
- 1009
- Advantage
- 58
- Tel
- 027-027-65385071 17771822910
- Fax
- 027-65526669
- shelleyl.meng@foxmail.com
- Country
- China
- ProdList
- 2354
- Advantage
- 58
- Tel
- 19135651983 19135651206
- 243332738@qq.com
- Country
- China
- ProdList
- 908
- Advantage
- 58
- Tel
- 027-027-65526929 17771822910
- hxry001@foxmail.com
- Country
- China
- ProdList
- 60
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
View Lastest Price from Methyl 3-aminopropionate hydrochloride manufacturers
- Product
- Methyl 3-aminopropionate hydrochloride 3196-73-4
- Price
- US $0.00/G/KG
- Min. Order
- 1G/KG
- Purity
- 99%
- Supply Ability
- 100MT
- Release date
- 2025-04-23
- Product
- Methyl 3-aminopropionate hydrochloride 3196-73-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 50kg/month
- Release date
- 2023-01-09
- Product
- β-Ala-Ome.HCl 3196-73-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-03-13