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ZLN005

Product Name
ZLN005
CAS No.
49671-76-3
Chemical Name
ZLN005
Synonyms
ZLN005;CS-1004;ZLN005, >=98%;ZLN 005; ZLN-005;2-(4-tert-Butylphenyl)benzimidazole;2-(4-tert-Butylphenyl)-1H-benzimidazole;2-(4-TERT-BUTYLPHENYL)-1H-BENZO[D]IMIDAZOLE;2-[4-(1,1-dimethylethyl)phenyl]-1H-benzimidazole;1H-Benzimidazole, 2-[4-(1,1-dimethylethyl)phenyl]-;2-(4-tert-Butylphenyl)benzimidazole ZLN005
CBNumber
CB82681122
Molecular Formula
C17H18N2
Formula Weight
250.34
MOL File
49671-76-3.mol
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ZLN005 Property

Melting point:
257-258℃
Boiling point:
415.3±38.0 °C(Predicted)
Density 
1.102±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO: soluble10mg/mL, clear
pka
11.52±0.10(Predicted)
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0802
Product name
ZLN005
Purity
≥95% (HPLC)
Packaging
10mg
Price
$78.1
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0802
Product name
ZLN005
Purity
≥95% (HPLC)
Packaging
50mg
Price
$303
Updated
2024/03/01
Cayman Chemical
Product number
14121
Product name
ZLN005
Purity
≥98%
Packaging
5mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
14121
Product name
ZLN005
Purity
≥98%
Packaging
10mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
14121
Product name
ZLN005
Purity
≥98%
Packaging
25mg
Price
$134
Updated
2024/03/01
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ZLN005 Chemical Properties,Usage,Production

Description

Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis. ZLN005 is a small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM. Chronic administration of 15 mg/kg/day ZLN005 to diabetic db/db mice increased PGC-1α and downstream gene transcription in skeletal muscle, increasing fat oxidation and improving glucose tolerance, pyruvate tolerance, and insulin sensitivity.

Uses

ZLN005 increaces PGC-1α and downstream gene transcription in skeletal muscles and increases fat oxidation and improved the glucose tolerance, pyruvate tolerance, and insulin sensitivity of diabetic db/db mice.

ZLN005 Preparation Products And Raw materials

Raw materials

Preparation Products

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ZLN005 Suppliers

China 99 India 2 The Netherlands 1 United States 14 Global 116
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View Lastest Price from ZLN005 manufacturers

Career Henan Chemical Co
Product
ZLN-005 49671-76-3
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
96%
Supply Ability
10kg
Release date
2019-09-04

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  • 2-(4-TERT-BUTYLPHENYL)-1H-BENZO[D]IMIDAZOLE
  • 2-(4-tert-Butylphenyl)-1H-benzimidazole
  • 2-(4-tert-Butylphenyl)benzimidazole
  • ZLN005, >=98%
  • 2-[4-(1,1-dimethylethyl)phenyl]-1H-benzimidazole
  • 2-(4-tert-Butylphenyl)benzimidazole ZLN005
  • ZLN005 2-(4-tert-Butylphenyl)benzimidazole
  • ZLN005
  • CS-1004
  • ZLN 005; ZLN-005
  • 1H-Benzimidazole, 2-[4-(1,1-dimethylethyl)phenyl]-
  • 49671-76-3
  • Inhibitors