Sulfo-NHS-Biotin

ChemicalBook > CAS DataBase List > Sulfo-NHS-Biotin

Product Name: Sulfo-NHS-Biotin
CAS No.: 119616-38-5
Chemical Name: Sulfo-NHS-Biotin
Synonyms: CAS_119616-38-5;SULFOBIOTIN-NHS;SULFO-NHS-BIOTIN;BIOTIN SULFO-OSU;SULPHO NHS BIOTIN;Biotin-Sulfo-NHS ester;SULFOSUCCINIMIDOBIOTIN;SULPHOSUCCINIMIDO BIOTIN;Sulfosuccinimidyl biotin;Biotin-Sulfo-Succinimidyl
CBNumber: CB8277468
Molecular Formula: C14H18N3NaO8S2
Formula Weight: 443.43
MOL File: 119616-38-5.mol

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Sulfo-NHS-Biotin Property

storage temp.: -20°C
solubility: H₂O: 10 mg/mL
form: powder
Water Solubility: H2O: 10mg/mL
DMF: 50mg/mL
CAS DataBase Reference: 119616-38-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38-63
Safety Statements: 22-26-36
WGK Germany: 3
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B5161
Product name: Biotin 3-sulfo-N-hydroxysuccinimide ester sodium salt
Purity: ≥90% (TLC), powder
Packaging: 10mg
Price: $121
Updated: 2024/03/01

Sigma-Aldrich

Product number: B5161
Product name: Biotin 3-sulfo-N-hydroxysuccinimide ester sodium salt
Purity: ≥90% (TLC), powder
Packaging: 50mg
Price: $400
Updated: 2024/03/01

Sigma-Aldrich

Product number: 203118
Product name: Biotin-NHS, Water-Soluble
Packaging: 50MG
Price: $188
Updated: 2024/03/01

TRC

Product number: S699260
Product name: Sulfo-NHS-BiotinSodiumSalt
Packaging: 100mg
Price: $145
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 67094
Product name: Sulfo-NHS-BiotinSodiumSalt
Packaging: 500mg
Price: $1125
Updated: 2021/12/16

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Sulfo-NHS-Biotin Chemical Properties,Usage,Production

Description

Sulfo-NHS-Biotin is a linker containing a sulfo-NHS moiety and a biotin group. Sulfo-NHS enables control and modification of carbodiimide crosslinking reactions involving activation of carboxylates for conjugation with primary amines. The terminal biotinylation can react with amine molecules in the presence of activator EDC or HATU.

Chemical Properties

1.3

Uses

apoptosis probe, cell permeable fluorescent Ca2+-sensitive dye for cystolic Ca2+ assays

Uses

Sulfo-NHS-Biotin is a biotinylation reagent used for biotinylating antibody or protein that can then be used for protein detection or immobilization studies when used in conjunction with streptavidin and immobilized streptavidin. Sulfo-NHS-Biotin was shown to work most effectively when targeting cell surface proteins.

General Description

Biotin:avidin second antibody signal systems involve the conjugation of biotin to a secondary antibody. Once the secondary antibody binds to a target primary antibody in an immunochemical assay, the signal is developed by allowing avidin which has been conjugated to an enzyme or signal molecule to bind to the antibody associated biotin molecule.

Biological Activity

sulfo-nhs-biotin (n-hydroxysulfosuccinimidobiotin) is an amine-reactive biotinylation reagent. the most common amine-reactive biotinylation reagents can be divied into two basic types, n-hydroxysuccinimide (nhs) esters and carboxylates. generally, nhs esters biotinylation reagent contains a reactive nhs ring structure that reacts with an amine on the carbonyl group of a protein or other molecules through nucleophilic attack subsequently forming a stable amide linkage and releasing the nhs group. due to the insolubility of nhs-biotin in aqueous environments, sulfo-nhs-biotin, a water-soluble analog of nhs-biotin, has been developed by attaching a negatively charged sulfonate group on the nhs ring structure, which can be added directly to aqueous reactions without the need for organic solvent dissolution.bioconjugate techniques , 2nd ed. by greg t.hermanson (pierce biotechnology, thermo fisher scientific, rockford, il). academic press (an imprint of elsevier): london, amsterdam, burlington, san diego . 2008. isbn 978-0-12-370501-3.

Sulfo-NHS-Biotin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sulfo-NHS-Biotin manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Biotin-Sulfo-NHS ester 119616-38-5
Price: US $0.00/mg
Min. Order: 250mg
Purity: >95.00%
Supply Ability: 25g
Release date: 2024-03-30

Career Henan Chemical Co

Product: Sulfo-NHS-Biotin 119616-38-5
Price: US $0.01/KG
Min. Order: 1KG
Purity: 98%； 99%
Supply Ability: 1kg; 5kg; 10kg；25kg
Release date: 2020-01-07

119616-38-5, Sulfo-NHS-BiotinRelated Search:

Biotin-PEG7-Amine DBCO-S-S-PEG3-Biotin N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE BIOTIN-NHS BIOTIN HYDRAZIDE methyl 5-[(1S,2S,5R)-7-oxo-3-thia-6,8-diazabicyclo[3.3.0]oct-2-yl]pent anoate BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER Sulfo-NHS-Biotin N-Hydroxysulfosuccinimide sodium salt N-Octyl pyrrolidone 3-(acetylamino)propanesulphonic acid ACETYLDIFORMAMIDE N-propionylsuccinimide N-ACETYL SUCCINIMIDE 1-Heptyl-2-Pyrrolidone N-AMYLSUCCINIMIDE D-DESTHIOBIOTIN 7,8-DIAMINOPELARGONIC ACID

Biotin 3-sulfo-N-hydroxysuccinimide

CAS_119616-38-5

Biotin-Sulfo-Succinimidyl

Biotin-Sulfo-NHS ester

3-Pyrrolidinesulfonic acid, 1-[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]iMidazol-4-yl)-1-oxopentyl]oxy]-2,5-dioxo-, MonosodiuM salt

SulfosucciniMidobiotin(Sulfo-NHS-Biotin)

Biotinyl-N-hydroxy-sulfosucciniMide

BIOTIN (LONG ARM) NHS, WATER SOLUBLE

BIOTIN-NHS, WATER-SOLUBLE

BIOTIN 3-SULFO-N-HYDROXY-SUCCINIMIDE ESTER SODIUM SALT

5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-4-YL)-PENTANOIC ACID 2,5-DIOXO-3-SULFO-PYRROLIDIN-1-YL ESTER SODIUM SALT

SULFOSUCCINIMIDOBIOTIN

SULFOSUCCINIMIDOBIOTIN SODIUM SALT

SULPHOSUCCINIMIDO BIOTIN

SULPHO NHS BIOTIN

SULFOBIOTIN-NHS

SULFO-NHS-BIOTIN

biotin 3-sulfo-N-hydroxysuccinimide ester

BIOTIN SULFO-OSU

biotin 3-sulfo-N-hydroxysuccinimide*ester sodium

Sulfosuccinimidyl biotin

BiotinN-hydroxy-sulfosuccinimideester

Sulfo-NHS-Biotin Sodium Salt

Sulfo-NHS-Biotin, NHS-ester biotinylation reagent

Sulfo-NHS-Biotin, 10 mM in DMSO

119616-38-5

C14H18N3NaO8S2

C14H18N3S2O8Na

C14H18N3O8S2Na

Proteomics and Protein Expression

Protein Modification

Proteomics

Reagents for Biotinylating Amines

BioChemical

Biotinylation

Biotinylation Reagents

BiotinylationReagents