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Sulfo-NHS-Biotin

Product Name
Sulfo-NHS-Biotin
CAS No.
119616-38-5
Chemical Name
Sulfo-NHS-Biotin
Synonyms
CAS_119616-38-5;SULFOBIOTIN-NHS;SULFO-NHS-BIOTIN;BIOTIN SULFO-OSU;SULPHO NHS BIOTIN;Biotin-Sulfo-NHS ester;SULFOSUCCINIMIDOBIOTIN;SULPHOSUCCINIMIDO BIOTIN;Sulfosuccinimidyl biotin;Biotin-Sulfo-Succinimidyl
CBNumber
CB8277468
Molecular Formula
C14H18N3NaO8S2
Formula Weight
443.43
MOL File
119616-38-5.mol
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Sulfo-NHS-Biotin Property

storage temp. 
-20°C
solubility 
H2O: 10 mg/mL
form 
powder
CAS DataBase Reference
119616-38-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38-63
Safety Statements 
22-26-36
WGK Germany 
3
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B5161
Product name
Biotin 3-sulfo-N-hydroxysuccinimide ester sodium salt
Purity
≥90% (TLC), powder
Packaging
10mg
Price
$121
Updated
2024/03/01
Sigma-Aldrich
Product number
B5161
Product name
Biotin 3-sulfo-N-hydroxysuccinimide ester sodium salt
Purity
≥90% (TLC), powder
Packaging
50mg
Price
$400
Updated
2024/03/01
Sigma-Aldrich
Product number
203118
Product name
Biotin-NHS, Water-Soluble
Packaging
50MG
Price
$188
Updated
2024/03/01
TRC
Product number
S699260
Product name
Sulfo-NHS-BiotinSodiumSalt
Packaging
100mg
Price
$145
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
67094
Product name
Sulfo-NHS-BiotinSodiumSalt
Packaging
500mg
Price
$1125
Updated
2021/12/16
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Sulfo-NHS-Biotin Chemical Properties,Usage,Production

Description

Sulfo-NHS-Biotin is a linker containing a sulfo-NHS moiety and a biotin group. Sulfo-NHS enables control and modification of carbodiimide crosslinking reactions involving activation of carboxylates for conjugation with primary amines. The terminal biotinylation can react with amine molecules in the presence of activator EDC or HATU.

Chemical Properties

1.3

Uses

Sulfo-NHS-Biotin is a biotinylation reagent used for biotinylating antibody or protein that can then be used for protein detection or immobilization studies when used in conjunction with streptavidin and immobilized streptavidin. Sulfo-NHS-Biotin was shown to work most effectively when targeting cell surface proteins.

Uses

apoptosis probe, cell permeable fluorescent Ca2+-sensitive dye for cystolic Ca2+ assays

Uses

Sulfo-NHS-Biotin is a biotinylation reagent used for biotinylating antibody or protein that can then be used for protein detection or immobilization studies when used in conjunction with streptavidin and immobilized streptavidin. Sulfo-NHS-Biotin was shown to work most effectively when targeting cell surface proteins.

General Description

Biotin:avidin second antibody signal systems involve the conjugation of biotin to a secondary antibody. Once the secondary antibody binds to a target primary antibody in an immunochemical assay, the signal is developed by allowing avidin which has been conjugated to an enzyme or signal molecule to bind to the antibody associated biotin molecule.

Biological Activity

sulfo-nhs-biotin (n-hydroxysulfosuccinimidobiotin) is an amine-reactive biotinylation reagent. the most common amine-reactive biotinylation reagents can be divied into two basic types, n-hydroxysuccinimide (nhs) esters and carboxylates. generally, nhs esters biotinylation reagent contains a reactive nhs ring structure that reacts with an amine on the carbonyl group of a protein or other molecules through nucleophilic attack subsequently forming a stable amide linkage and releasing the nhs group. due to the insolubility of nhs-biotin in aqueous environments, sulfo-nhs-biotin, a water-soluble analog of nhs-biotin, has been developed by attaching a negatively charged sulfonate group on the nhs ring structure, which can be added directly to aqueous reactions without the need for organic solvent dissolution.bioconjugate techniques , 2nd ed. by greg t.hermanson (pierce biotechnology, thermo fisher scientific, rockford, il). academic press (an imprint of elsevier): london, amsterdam, burlington, san diego . 2008. isbn 978-0-12-370501-3.

Sulfo-NHS-Biotin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sulfo-NHS-Biotin manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Biotin-Sulfo-NHS ester 119616-38-5
Price
US $0.00/mg
Min. Order
250mg
Purity
>95.00%
Supply Ability
25g
Release date
2024-03-30
Career Henan Chemical Co
Product
Sulfo-NHS-Biotin 119616-38-5
Price
US $0.01/KG
Min. Order
1KG
Purity
98%; 99%
Supply Ability
1kg; 5kg; 10kg;25kg
Release date
2020-01-07

119616-38-5, Sulfo-NHS-BiotinRelated Search:


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  • biotin 3-sulfo-N-hydroxysuccinimide ester
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  • biotin 3-sulfo-N-hydroxysuccinimide*ester sodium
  • Sulfosuccinimidyl biotin
  • BiotinN-hydroxy-sulfosuccinimideester
  • Sulfo-NHS-Biotin Sodium Salt
  • 119616-38-5
  • C14H18N3NaO8S2
  • C14H18N3S2O8Na
  • C14H18N3O8S2Na
  • Proteomics and Protein Expression
  • Protein Modification
  • Proteomics
  • Reagents for Biotinylating Amines
  • BioChemical
  • Biotinylation
  • Biotinylation Reagents
  • BiotinylationReagents