4-Fluorophenyl isocyanate
- Product Name
- 4-Fluorophenyl isocyanate
- CAS No.
- 1195-45-5
- Chemical Name
- 4-Fluorophenyl isocyanate
- Synonyms
- 1-FLUORO-4-ISOCYANATOBENZENE;SB 01844;NSC82348;AKOS B022528;ZINC00164841;F14335_ALDRICH;EINECS 214-799-0;4-Fluorphenylisocyanat;4-Fluorophenyl isocyate;4-FLUOROPHENYL ISOCYANATE
- CBNumber
- CB8292434
- Molecular Formula
- C7H4FNO
- Formula Weight
- 137.11
- MOL File
- 1195-45-5.mol
4-Fluorophenyl isocyanate Property
- Boiling point:
- 55 °C8 mm Hg(lit.)
- Density
- 1.206 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.5141(lit.)
- Flash point:
- 127 °F
- storage temp.
- 2-8°C
- form
- Liquid
- color
- Clear colorless to light yellow
- Water Solubility
- Decomposes
- Sensitive
- Moisture Sensitive/Lachrymatory
- BRN
- 471609
- CAS DataBase Reference
- 1195-45-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,T,C,T+
- Risk Statements
- 20/21/22-36-42-36/37/38-26
- Safety Statements
- 23-26-36/37-45-38-28A
- RIDADR
- UN 3080 6.1/PG 2
- WGK Germany
- 3
- F
- 1-10-19
- Hazard Note
- Toxic/Corrosive/Lachrymatory/Moisture Sensitive
- HazardClass
- 3
- PackingGroup
- III
- HS Code
- 29291090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F14335
- Product name
- 4-Fluorophenyl isocyanate
- Purity
- 99%
- Packaging
- 5g
- Price
- $45.4
- Updated
- 2025/07/31
- Product number
- F14335
- Product name
- 4-Fluorophenyl isocyanate
- Purity
- 99%
- Packaging
- 10g
- Price
- $90.7
- Updated
- 2025/07/31
- Product number
- I0339
- Product name
- 4-Fluorophenyl Isocyanate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $48
- Updated
- 2025/07/31
- Product number
- I0339
- Product name
- 4-Fluorophenyl Isocyanate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $151
- Updated
- 2025/07/31
- Product number
- 276053
- Product name
- 4-Fluorophenyl isocyanate
- Packaging
- 10g
- Price
- $337
- Updated
- 2021/12/16
4-Fluorophenyl isocyanate Chemical Properties,Usage,Production
Chemical Properties
CLEAR LIGHT YELLOW TO AMBER LIQUID
Uses
4-Fluorophenyl isocyanate acts as a reagent in the preparation of tris-ureas as transmembrane anion transporters, solid phase combinatorial synthesis of peptides as integrin inhibitors.
Purification Methods
Purify the isocyanate by repeated fractionation through an efficient column. If IR indicates that there is too much urea (in the presence of moisture the symmetrical urea is formed), then dissolve it in dry EtOH-free CHCl3, filter, evaporate and distil it. It is a pungent LACHRYMATORY liquid. [See Hardy J Chem Soc 2011 1934, and Hickinbottom Reactions of Organic Compounds Longmans p493 1957.] 4-Fluorophenyl isothiocyanate [1544-68 -9] M 153.2, m 24 -26o, 26 -27o, b 66o/2mm, 2 1 5o/atm, 228o/760mm, n D 1.6116. A likely impurity is the symmetrical thiourea. Dissolve the isothiocyanate in dry CHCl3, filter and distil the residue in a vacuum. It can also be steam distilled, the oily layer is separated, dried over CaCl2 and distilled in vacuo. Bis-(4-fluorophenyl)thiourea has m 145o (from aqueous EtOH). [Browne & Dyson J Chem Soc 3285 1931, Buu Hoi et al. J Chem Soc 1573 1955, Olander Org Synth Coll Vol I 448 1941 ].
4-Fluorophenyl isocyanate Preparation Products And Raw materials
Raw materials
Preparation Products
4-Fluorophenyl isocyanate Suppliers
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View Lastest Price from 4-Fluorophenyl isocyanate manufacturers
- Product
- 4-Fluorophenyl isocyanate 1195-45-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10000KGS
- Release date
- 2024-11-14
- Product
- 4-Fluorophenyl isocyanate 1195-45-5
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-20