ChemicalBook > CAS DataBase List > O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE

Product Name
O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
CAS No.
57981-02-9
Chemical Name
O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
Synonyms
PFBHA;O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine;PFBHA HCL;Nsc153392;FLOROX REAGENT;FLOROX(TM) REAGENT;TIMTEC-BB SBB003152;Pentafluorobenzylhydroxylamine;PENTAFLUOROBENZYLHYDROXYLAMINE HCL;(2,3,4,5,6-Pentafluorobenzyl)oxyamine
CBNumber
CB8307815
Molecular Formula
C7H5ClF5NO
Formula Weight
249.57
MOL File
57981-02-9.mol
More
Less

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Property

Melting point:
227 °C (subl.)(lit.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: 5%, clear
form 
powder to crystal
color 
White
PH
pH(5g/l, 25℃) : 2.0～3.0
Water Solubility 
Soluble in water.
BRN 
4031190
CAS DataBase Reference
57981-02-9(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25
WGK Germany 
3
F 
10
HazardClass 
IRRITANT
HS Code 
29280000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
194484
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride
Purity
≥98%
Packaging
250mg
Price
$58.7
Updated
2024/03/01
Sigma-Aldrich
Product number
194484
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride
Purity
≥98%
Packaging
1g
Price
$159
Updated
2024/03/01
TCI Chemical
Product number
P0822
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation]
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$123
Updated
2024/03/01
TCI Chemical
Product number
P0822
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation]
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$465
Updated
2024/03/01
Alfa Aesar
Product number
A18368
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride, 99+%
Packaging
0.25g
Price
$53.65
Updated
2024/03/01
More
Less

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used in the preparation of oximes of steroids having keto group. It is used as a derivatization reagent in the determination of thromboxane B2, prostaglandins, amygdalin and a variety of aldehydes, ketones and acids. It is a versatile reagent utilized for the detection of carbonyl-containing compounds by gas chromatography (GC), gas chromatography mass spectrometry (GC-MS) and other methods. As a derivatization reagent, it is also used for EC/LC analysis of keto-steroids and carbohydrates.

Uses

PFBHA.HCl has been used for derivatization of metabolites with carbonyl groups followed by analysis via GC-MS. It has also been used in aldehyde derivatization followed by aldehydic hydrolysis using GC/MS.

Uses

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used:

  • In the preparation of oximes of steroids-bearing keto group.
  • As a derivatization reagent in the determination of thromboxane B2, prostaglandins, amygdalin, and a variety of aldehydes, ketones, and acids.
It is a versatile reagent used for the detection of carbonyl-containing compounds by GC, GC-MS, and other methods.

General Description

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride (PFBHA.HCl) is a derivatizing agent.

Purification Methods

Recrystallise the salt from EtOH to form colourless leaflets. Drying the compound at high vacuum and elevated temperature will result in losses by sublimation. [Youngdale J Pharm Sci 65 625 1976, Wehner & Handke J Chromatog 177 237 1979, Nambara et al. give incorrect m as 115-116o J Chromatogr 114 81 1975.]

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Hexane Hydrazinium hydroxide solution N-Hydroxyphthalimide N,N-Dimethylformamide Acetone Bromopentafluorobenzene Triethylamine Hydrogen bromide Tetrahydrofuran Diethyl ether Lithium Aluminum Hydride Hydrochloric acid Dichloromethane Methanol Sodium hydroxide Magnesium N-Methylformanilide Sulfuric acid

Preparation Products

More
Less

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Suppliers

Americas 1 Belgium 2 Canada 1 China 110 Europe 1 France 3 Germany 6 India 8 Japan 7 Russia 1 Switzerland 1 The Netherlands 1 United Kingdom 7 United States 33 Global 182
Zhengzhou Guancheng Laboratory equipment Sales
Tel
0371-88888888 272369594
Fax
QQ:272369594
Email
2723695949@qq.com
Country
China
ProdList
4939
Advantage
50
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376090521
Fax
025-85766769
Email
sales@habotech.com
Country
China
ProdList
969
Advantage
60
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19179
Advantage
64
More
Less

View Lastest Price from O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE 57981-02-9
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-20

57981-02-9, O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDERelated Search:

2,3,4,5-Tetrafluorobenzyl alcohol 2,3,4,5,6-PENTAFLUOROTOLUENE 2,6-Difluorobenzyl alcohol 2,3-Difluorobenzyl alcohol 2,3,5-Trifluorobenzyl alcohol 2,3,4,6-TETRAFLUOROBENZYL ALCOHOL Methoxyammonium chloride 2,4-Difluorobenzyl alcohol 3,4,5-Trifluorobenzenemethanol 3,5-Difluorobenzyl alcohol Ethoxyamine hydrochloride 2,3,6-TRIFLUOROBENZYL ALCOHOL 2,5-Difluorobenzyl alcohol 3,4-Difluorobenzyl alcohol 2,3,4-Trifluorobenzyl alcohol O-Benzylhydroxylamine hydrochloride 2,3,4,5,6-Pentafluorobenzyl alcohol 1,2,3,5-Tetrafluorobenzene

  • 2-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • FLOROX REAGENT
  • FLOROX(TM) REAGENT
  • PFBHA
  • PFBHA HCL
  • PENTAFLUOROBENZYLHYDROXYLAMINE HCL
  • O-(PENTAFLUOROBENZYL)HYDROXYAMINE HYDROCHLORIDE
  • O-(PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • O-PENTAFLUOROBENZYLHYDROXYLAMINE HYDROCHLORIDE IN PYRIDINE
  • O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • TIMTEC-BB SBB003152
  • 0-(2,3,4,5,6-Pentafluorobenzyl) Hydroxylamine Hydrochloride
  • O-(Pentafluorobenzyl)hydroxylamine hydrochloride 97%
  • O-(2,3,4,5,6-pentafluorobenzyl)*hydroxylamine hyd
  • O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYL- AMINE HYDROCHLORIDE, 99+%
  • O-(2,3,4,5,6-PENTAFLUOROBENZYL)*HYDROXYL AMINE HYDRO
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamineHCl
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride 97%
  • O-(Pentafluorobenzyl)hydroxylaminehydrochloride97%
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation]
  • (2,3,4,5,6-Pentafluorobenzyl)oxyamine
  • [(2,3,4,5,6-Pentafluorobenzyl)oxy]amine
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine
  • O-(Pentafluorophenylmethyl)hydroxylamine
  • Pentafluorobenzylhydroxylamine
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine·hydrochloric acid
  • Pentafluorobenzylhydroxylamine·hydrochloride
  • 1-[(Aminooxy)methyl]-2,3,4,5,6-pentafluorobenzene hydrochloride
  • 2,3,4,5,6-Pentafluorobenzyloxyamine hydrochloride
  • N-[(2,3,4,5,6-Pentafluorobenzyl)oxy]amine hydrochloride
  • Nsc153392
  • O-[(2,3,4,5,6-Pentafluorophenyl)methyl]hydroxylamine hydrochloride
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylaMine hydrochloride >=98%
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylaMine hydrochloride, derivatization grade
  • Hydroxylamine, O-[(2,3,4,5,6-pentafluorophenyl)methyl]-, hydrochloride (1:1)
  • 6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride, 99%, derivatization grade
  • Method 556 PFBHA Reagent@15.0 mg/mL in Water
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamineHydrochloride[forOximePreparation]&gt
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride for GC derivatization
  • O-[(2,3,4,5,6-pentafluorophenyl)methyl]hydroxylamine
  • 57981-02-9
  • C7H5ClF5NO
  • C7H4F5NO
  • C6F5CH2ONH2HCl
  • C7H4F5NOHCl
  • C7H4F5NOClH
  • Biochemicals and Reagents
  • Building Blocks
  • BioChemical
  • Nitrogen Compounds
  • Luminescent Compounds/Detection
  • Organic Building Blocks
  • Derivatization agents
  • Boronic Acid, etc. (GC Derivatizing Reagents)
  • GC Derivatizing Reagents
  • Hydroxylamines (O-Substituted)
  • Hydroxylamines