ChemicalBook > CAS DataBase List > O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE

Product Name
O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
CAS No.
57981-02-9
Chemical Name
O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
Synonyms
PFBHA;O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine;PFBHA HCL;Nsc153392;FLOROX REAGENT;FLOROX(TM) REAGENT;TIMTEC-BB SBB003152;Pentafluorobenzylhydroxylamine;PENTAFLUOROBENZYLHYDROXYLAMINE HCL;(2,3,4,5,6-Pentafluorobenzyl)oxyamine
CBNumber
CB8307815
Molecular Formula
C7H5ClF5NO
Formula Weight
249.57
MOL File
57981-02-9.mol
More
Less

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Property

Melting point:
227 °C (subl.)(lit.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: 5%, clear
form 
powder to crystal
color 
White
PH
pH(5g/l, 25℃) : 2.0～3.0
Water Solubility 
Soluble in water.
BRN 
4031190
CAS DataBase Reference
57981-02-9(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25
WGK Germany 
3
F 
10
HazardClass 
IRRITANT
HS Code 
29280000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
194484
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride
Purity
≥98%
Packaging
250mg
Price
$58.7
Updated
2024/03/01
Sigma-Aldrich
Product number
194484
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride
Purity
≥98%
Packaging
1g
Price
$159
Updated
2024/03/01
TCI Chemical
Product number
P0822
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation]
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$123
Updated
2024/03/01
TCI Chemical
Product number
P0822
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation]
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$465
Updated
2024/03/01
Alfa Aesar
Product number
A18368
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride, 99+%
Packaging
0.25g
Price
$53.65
Updated
2024/03/01
More
Less

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used in the preparation of oximes of steroids having keto group. It is used as a derivatization reagent in the determination of thromboxane B2, prostaglandins, amygdalin and a variety of aldehydes, ketones and acids. It is a versatile reagent utilized for the detection of carbonyl-containing compounds by gas chromatography (GC), gas chromatography mass spectrometry (GC-MS) and other methods. As a derivatization reagent, it is also used for EC/LC analysis of keto-steroids and carbohydrates.

Uses

PFBHA.HCl has been used for derivatization of metabolites with carbonyl groups followed by analysis via GC-MS. It has also been used in aldehyde derivatization followed by aldehydic hydrolysis using GC/MS.

Uses

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used:

  • In the preparation of oximes of steroids-bearing keto group.
  • As a derivatization reagent in the determination of thromboxane B2, prostaglandins, amygdalin, and a variety of aldehydes, ketones, and acids.
It is a versatile reagent used for the detection of carbonyl-containing compounds by GC, GC-MS, and other methods.

General Description

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride (PFBHA.HCl) is a derivatizing agent.

Purification Methods

Recrystallise the salt from EtOH to form colourless leaflets. Drying the compound at high vacuum and elevated temperature will result in losses by sublimation. [Youngdale J Pharm Sci 65 625 1976, Wehner & Handke J Chromatog 177 237 1979, Nambara et al. give incorrect m as 115-116o J Chromatogr 114 81 1975.]

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Hexane Hydrazinium hydroxide solution N-Hydroxyphthalimide N,N-Dimethylformamide Acetone Bromopentafluorobenzene Triethylamine Hydrogen bromide Tetrahydrofuran Diethyl ether Lithium Aluminum Hydride Hydrochloric acid Dichloromethane Methanol Sodium hydroxide Magnesium N-Methylformanilide Sulfuric acid

Preparation Products

More
Less

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Suppliers

Americas 1 Belgium 2 Canada 1 China 110 Europe 1 France 3 Germany 6 India 8 Japan 7 Russia 1 Switzerland 1 The Netherlands 1 United Kingdom 7 United States 33 Global 182
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
FUJIFILM Wako Pure Chemical Corporation
Tel
--
Fax
--
Email
ffwk-cservice@fujifilm.com
Country
Japan
ProdList
6222
Advantage
58
TCI Japan
Tel
--
Fax
--
Email
@TCIchemicals.com
Country
Japan
ProdList
2741
Advantage
58
Kanto Chemical Co. Inc.
Tel
--
Fax
--
Email
kanto-61@gms.kanto.co.jp
Country
Japan
ProdList
530
Advantage
58
Nacalai Tesque, Inc.
Tel
--
Fax
--
Email
info-tech@nacalai.co.jp
Country
Japan
ProdList
6046
Advantage
75
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
Kanto Chemical Co., Inc.
Tel
--
Fax
--
Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6756
Advantage
74
More
Less

View Lastest Price from O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE 57981-02-9
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-20

57981-02-9, O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDERelated Search:

2,3,4,5-Tetrafluorobenzyl alcohol 2,3,4,5,6-PENTAFLUOROTOLUENE 2,6-Difluorobenzyl alcohol 2,3-Difluorobenzyl alcohol 2,3,5-Trifluorobenzyl alcohol 2,3,4,6-TETRAFLUOROBENZYL ALCOHOL Methoxyammonium chloride 2,4-Difluorobenzyl alcohol 3,4,5-Trifluorobenzenemethanol 3,5-Difluorobenzyl alcohol Ethoxyamine hydrochloride 2,3,6-TRIFLUOROBENZYL ALCOHOL 2,5-Difluorobenzyl alcohol 3,4-Difluorobenzyl alcohol 2,3,4-Trifluorobenzyl alcohol O-Benzylhydroxylamine hydrochloride 2,3,4,5,6-Pentafluorobenzyl alcohol 1,2,3,5-Tetrafluorobenzene

  • 2-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • FLOROX REAGENT
  • FLOROX(TM) REAGENT
  • PFBHA
  • PFBHA HCL
  • PENTAFLUOROBENZYLHYDROXYLAMINE HCL
  • O-(PENTAFLUOROBENZYL)HYDROXYAMINE HYDROCHLORIDE
  • O-(PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • O-PENTAFLUOROBENZYLHYDROXYLAMINE HYDROCHLORIDE IN PYRIDINE
  • O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • TIMTEC-BB SBB003152
  • 0-(2,3,4,5,6-Pentafluorobenzyl) Hydroxylamine Hydrochloride
  • O-(Pentafluorobenzyl)hydroxylamine hydrochloride 97%
  • O-(2,3,4,5,6-pentafluorobenzyl)*hydroxylamine hyd
  • O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYL- AMINE HYDROCHLORIDE, 99+%
  • O-(2,3,4,5,6-PENTAFLUOROBENZYL)*HYDROXYL AMINE HYDRO
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamineHCl
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride 97%
  • O-(Pentafluorobenzyl)hydroxylaminehydrochloride97%
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation]
  • (2,3,4,5,6-Pentafluorobenzyl)oxyamine
  • [(2,3,4,5,6-Pentafluorobenzyl)oxy]amine
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine
  • O-(Pentafluorophenylmethyl)hydroxylamine
  • Pentafluorobenzylhydroxylamine
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine·hydrochloric acid
  • Pentafluorobenzylhydroxylamine·hydrochloride
  • 1-[(Aminooxy)methyl]-2,3,4,5,6-pentafluorobenzene hydrochloride
  • 2,3,4,5,6-Pentafluorobenzyloxyamine hydrochloride
  • N-[(2,3,4,5,6-Pentafluorobenzyl)oxy]amine hydrochloride
  • Nsc153392
  • O-[(2,3,4,5,6-Pentafluorophenyl)methyl]hydroxylamine hydrochloride
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylaMine hydrochloride >=98%
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylaMine hydrochloride, derivatization grade
  • Hydroxylamine, O-[(2,3,4,5,6-pentafluorophenyl)methyl]-, hydrochloride (1:1)
  • 6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride, 99%, derivatization grade
  • Method 556 PFBHA Reagent@15.0 mg/mL in Water
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamineHydrochloride[forOximePreparation]&gt
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride for GC derivatization
  • O-[(2,3,4,5,6-pentafluorophenyl)methyl]hydroxylamine
  • 57981-02-9
  • C7H5ClF5NO
  • C7H4F5NO
  • C6F5CH2ONH2HCl
  • C7H4F5NOHCl
  • C7H4F5NOClH
  • Biochemicals and Reagents
  • Building Blocks
  • BioChemical
  • Nitrogen Compounds
  • Luminescent Compounds/Detection
  • Organic Building Blocks
  • Derivatization agents
  • Boronic Acid, etc. (GC Derivatizing Reagents)
  • GC Derivatizing Reagents
  • Hydroxylamines (O-Substituted)
  • Hydroxylamines