Loxoprofen

Product Name: Loxoprofen
CAS No.: 68767-14-6
Chemical Name: Loxoprofen
Synonyms: IOXOPROFEN;2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid;2-[4-(2-OXO-CYCLOPENTYLMETHYL)-PHENYL]-PROPIONIC ACID;A-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID;KOLOXO;LOXOPROFEN;Loxoprofene;Loxoprofeno;Loxoprofen-d6;Loxoprofen RS
CBNumber: CB8311755
Molecular Formula: C15H18O3
Formula Weight: 246.31
MOL File: 68767-14-6.mol

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Loxoprofen Property

Melting point:: 108.5-111°
Boiling point:: bp0.3 190-195°
Density: 1.182±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: solid
pka: 4.39±0.10(Predicted)
color: White to Off-White
Merck: 14,5589
InChI: InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)
InChIKey: YMBXTVYHTMGZDW-UHFFFAOYSA-N
SMILES: C(C1CCCC1=O)C1C=CC(C(C)C(=O)O)=CC=1
CAS DataBase Reference: 68767-14-6(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
HS Code: 2918.99.3000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: L0664
Product name: Loxoprofen
Packaging: 5mg
Price: $386
Updated: 2024/03/01

TCI Chemical

Product number: L0244
Product name: Loxoprofen
Purity: >97.0%(HPLC)(T)
Packaging: 5g
Price: $108
Updated: 2024/03/01

TRC

Product number: L472905
Product name: Loxoprofen
Packaging: 100mg
Price: $185
Updated: 2021/12/16

AK Scientific

Product number: F995
Product name: Loxoprofen
Packaging: 5g
Price: $127
Updated: 2021/12/16

ChemScene

Product number: CS-2760
Product name: Loxoprofen
Purity: 99.76%
Packaging: 200mg
Price: $144
Updated: 2021/12/16

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Loxoprofen Chemical Properties,Usage,Production

Uses

antiinflammatory, analgesic

Uses

Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.

Definition

ChEBI: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted to its active trans-alcohol metabolite following ora administration.

Loxoprofen Preparation Products And Raw materials

Raw materials

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester ETHYL PHENYLPROPIOLATE Cyclopentanecarboxylic acid

Preparation Products

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Loxoprofen Suppliers

Americas 1 China 287 Europe 4 Germany 2 India 12 Japan 1 Switzerland 2 United Kingdom 5 United States 34 Global 348

Apin Chemicals Limited (UK)

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Email: info@apinchemicals.com
Country: United Kingdom
ProdList: 6184
Advantage: 60

Leancare Ltd.

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Fax: --
Email: enquiry@leancare.co.uk
Country: United Kingdom
ProdList: 6446
Advantage: 42

CARBONE SCIENTIFIC CO.,LTD

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Fax: --
Email: sales@carbonesci.com
Country: United Kingdom
ProdList: 6666
Advantage: 30

ETA SCIENTIFIC Co.,Ltd

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Fax: --
Email: sales@etascientific.com
Country: United Kingdom
ProdList: 6090
Advantage: 34

UK GREEN SCIENTIFIC CO.,LIMITED

Tel: --
Fax: --
Email: sales@gs-chem.com
Country: United Kingdom
ProdList: 6098
Advantage: 47

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View Lastest Price from Loxoprofen manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Loxoprofen Acid 68767-14-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%min
Supply Ability: 500kg/month
Release date: 2021-06-19

Shaanxi Dideu Medichem Co. Ltd

Product: Loxoprofen 68767-14-6
Price: US $1.00-1.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 50tons
Release date: 2020-04-29

Hebei Yanxi Chemical Co., Ltd.

Product: Loxoprofen 68767-14-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20T
Release date: 2023-03-10

68767-14-6, LoxoprofenRelated Search:

Chlorodimethylphenylsilane Kresoxim-methyl Methyl salicylate Methylcyclopentane Methanol Methylparaben Tribenuron methyl Tri(o-tolyl)phosphine Propionic acid Methyl acrylate PHENYL VALERATE 2,2-Bis(hydroxymethyl)propionic acid Basic Violet 1 Cyclopentane Silicone oil (high temperature) Loxoprofen Related Compound 5 Loxoprofen Related Compound 13 2-[(4-Acetylphenyl)methyl]cyclopentan-1-one

IOXOPROFEN

2-[4-[(2-Oxocyclopentan-1-yl)methyl]phenyl]propionic acid

KOLOXO

LOXOPROFEN

2-[4-(2-OXO-CYCLOPENTYLMETHYL)-PHENYL]-PROPIONIC ACID

A-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID

α-methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid

2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid

ALPHA-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID

Benzeneacetic acid, a-methyl-4-[(2-oxocyclopentyl)methyl]- (9CI)

Loxoprofen (base and/or unspecified salts)

α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid, Koloxo

Loxoprofen (high-melting polymorph)

Loxoprofen (low-melting polymorph)

2-[p-(2-Oxocyclopentylmethyl)phenyl]propionic acid

2-[4-[(2-ketocyclopentyl)methyl]phenyl]propionic acid

Loxoprofen USP

Loxoprofen See L472900

Benzeneacetic acid, a-Methyl-4-[(2-oxocyclopentyl)Methyl]-

Loxoprofen-d6

Loxoprofen RS

Loxoprofene

Loxoprofeno

Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-

Loxoprofen USP/EP/BP

Loxoprofen (10mM in DMSO)

Loxoprofen Impurity 67

Loxoprofen Impurity 68

Loxoprofen D7

Loxoprofen-d3Q: What is Loxoprofen-d3 Q: What is the CAS Number of Loxoprofen-d3

Loxoprofen API

Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-

2-(4-((2-(hydroxymethyl)-1,4-dioxaspiro[4.4]nonan-6-yl)methyl)phenyl)propanoic acid

68767-14-6

LOXONIN

Active Pharmaceutical Ingredients