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Dihydrodiol Ibrutinib

Product Name
Dihydrodiol Ibrutinib
CAS No.
1654820-87-7
Chemical Name
Dihydrodiol Ibrutinib
Synonyms
Ibrutinib Impurity 48;1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one;Dihydrodiol Ibrutinib;Ibrutinib iMpurity EQD;Ibrutinib Dihydrodiol R-Isomer;Ibrutinib Impurity 10(PCI-45227);Dihydrodiol Ibrutinib, PCI-45227;Ibrutinib Impurity 3 (PCI-45227) (Mixture ofDiastereomers);1-Propanone, 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2,3-dihydroxy-;1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one? (Ibrutinib Impurity）
CBNumber
CB83118908
Molecular Formula
C25H26N6O4
Formula Weight
474.51
MOL File
1654820-87-7.mol
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Dihydrodiol Ibrutinib Property

Melting point:
>93°C (dec.)
Boiling point:
790.3±60.0 °C(Predicted)
Density 
1.46±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
13.13±0.20(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

TRC
Product number
D450250
Product name
DihydrodiolIbrutinib
Packaging
2.5mg
Price
$155
Updated
2021/12/16
ChemScene
Product number
CS-0019899
Product name
Dihydrodiol-Ibrutinib
Packaging
5mg
Price
$350
Updated
2021/12/16
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Dihydrodiol Ibrutinib Chemical Properties,Usage,Production

Uses

Dihydrodiol Ibrutinib is a metabolite of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.

Dihydrodiol Ibrutinib Preparation Products And Raw materials

Raw materials

Preparation Products

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Dihydrodiol Ibrutinib Suppliers

China 47 India 1 United States 3 Global 51
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

1654820-87-7, Dihydrodiol IbrutinibRelated Search:

Ibrutinib Dimer Impurity (S)-3-Hydroxypiperidine Ibrutinib Impurity 24 (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one Ibrutinib 3-(2,4-dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)-Benzenamine 3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)benzenaMine 1,3-bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidin-1-yl)propan-1-one 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-3-chloropropan-1-one (S)-Ibrutinib (S)-1-Boc-3-hydroxypiperidine 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Nilotinib N-Oxide 3-Iodo-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide 4-(pyridine-2-yl) pyrimidin-2-amine 1-[(3R)-3-[4-amino-3-[4-(2,3,4,5,6-pentadeuteriophenoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2,3-dihydroxypropan-1-one Ibrutinib Impurity 28

  • Dihydrodiol Ibrutinib
  • Ibrutinib Dihydrodiol R-Isomer
  • Ibrutinib Impurity 3 (PCI-45227) (Mixture ofDiastereomers)
  • 1-Propanone, 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2,3-dihydroxy-
  • Ibrutinib iMpurity EQD
  • Ibrutinib Impurity 48
  • 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one
  • Dihydrodiol Ibrutinib, PCI-45227
  • Ibrutinib Impurity 10(PCI-45227)
  • 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one? (Ibrutinib Impurity）
  • 1654820-87-7