1,1,1-Trifluoroethyl-PEG3-Propargyl

Product Name: 1,1,1-Trifluoroethyl-PEG3-Propargyl
CAS No.: 1835759-73-3
Chemical Name: 1,1,1-Trifluoroethyl-PEG3-Propargyl
Synonyms: 1,1,1-Trifluoroethyl-PEG2-propargyl;1,1,1-Trifluoroethyl-PEG3-Propargyl;1-Propyne, 3-[2-[2-(2,2,2-trifluoroethoxy)ethoxy]ethoxy]-
CBNumber: CB83162800
Molecular Formula: C9H13F3O3
Formula Weight: 226.19
MOL File: 1835759-73-3.mol

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1,1,1-Trifluoroethyl-PEG3-Propargyl Property

Boiling point:: 243.5±35.0 °C(Predicted)
Density: 1.152±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22938
Product name: 1,1,1-Trifluoroethyl-PEG3-Propargyl
Purity: 98%
Packaging: 250mg
Price: $480
Updated: 2021/12/16

BroadPharm

Product number: BP-22938
Product name: 1,1,1-Trifluoroethyl-PEG3-Propargyl
Purity: 98%
Packaging: 500mg
Price: $750
Updated: 2021/12/16

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1,1,1-Trifluoroethyl-PEG3-Propargyl Chemical Properties,Usage,Production

Description

1,1,1-Trifluoroethyl-PEG3-Propargyl is a heterobifunctional reagent with an alkyne group and a trifluoroethyl group. The alkyne group reacts with azide compounds or biomolecules in copper catalyzed Click Chemistry to form a stable triazole linkage. The trifluoroethyl group is used to react with lysine and other primary amine groups in proteins, antibody and other molecules and surfaces.

Uses

1,1,1-Trifluoroethyl-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 1,1,1-Trifluoroethyl-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

1,1,1-Trifluoroethyl-PEG3-Propargyl Preparation Products And Raw materials

Raw materials

Preparation Products

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1,1,1-Trifluoroethyl-PEG3-Propargyl Suppliers

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View Lastest Price from 1,1,1-Trifluoroethyl-PEG3-Propargyl manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: 1,1,1-Trifluoroethyl-PEG3-propargyl 1835759-73-3
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-27

1835759-73-3, 1,1,1-Trifluoroethyl-PEG3-PropargylRelated Search:

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1,1,1-Trifluoroethyl-PEG2-propargyl

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1835759-73-3