5-CYANOPYRIMIDINE

Product Name: 5-CYANOPYRIMIDINE
CAS No.: 40805-79-6
Chemical Name: 5-CYANOPYRIMIDINE
Synonyms: 2-Butyne,3-bromo-;5-CYANOPYRIMIDINE;5-PyriMidinecarbonitrile;Pyrimidine-5-carbonitrile;5-Pyrimidinecarbonitrile (7CI,9CI);5-Cyanopyrimidine CAS NO.40805-79-6;5-CYANOPYRIMIDINE ISO 9001：2015 REACH;5-Cyanopyrimidine, 5-Cyano-1,3-diazine
CBNumber: CB8330259
Molecular Formula: C5H3N3
Formula Weight: 105.1
MOL File: 40805-79-6.mol

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5-CYANOPYRIMIDINE Property

Melting point:: 83.5-84 °C(Solv: ethanol (64-17-5))
Boiling point:: 237.6±13.0 °C(Predicted)
Density: 1.22±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
form: Solid
pka: 0.78±0.10(Predicted)
color: Pale Yellow

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Safety

Risk Statements: 36
Safety Statements: 26-24/25
Hazard Note: Harmful
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: C982145
Product name: 5-Cyanopyrimidine
Packaging: 250mg
Price: $385
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H37-1-Z4
Product name: Pyrimidine-5-carbonitrile
Packaging: 5G
Price: $320
Updated: 2021/12/16

Matrix Scientific

Product number: 068524
Product name: 5-Pyrimidinecarbonitrile
Purity: >95%
Packaging: 5g
Price: $324
Updated: 2021/12/16

Apolloscientific

Product number: OR11333
Product name: Pyrimidine-5-carbonitrile
Packaging: 5g
Price: $376
Updated: 2021/12/16

ChemScene

Product number: CS-M0923
Product name: pyrimidine-5-carbonitrile
Packaging: 10g
Price: $400
Updated: 2021/12/16

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5-CYANOPYRIMIDINE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

5-Cyanopyrimidine (cas# 40805-79-6) is a compound useful in organic synthesis.

Synthesis

40929-49-5

40805-79-6

General procedure for the synthesis of 5-cyanopyrimidine from pyrimidine-5-carboxamide: To a suspension of anhydrous dichloromethane (15 mL) containing pyrimidine-5-carboxamide (262 mg, 2.12 mmol) and triethylamine (481 mg, 4.24 mmol) was added slowly and dropwise a solution of trifluoroacetic anhydride (0.36 mL, dissolved in 4 mL of dichloromethane) at 0 °C. The reaction mixture was stirred at 0°C to room temperature for 2 hours. After completion of the reaction, it was quenched with water (2 mL) and the organic layer was washed sequentially with 1N NaOH solution (5 mL) and brine (2 x 5 mL). The organic phase was dried with anhydrous magnesium sulfate and subsequently concentrated under reduced pressure at less than 30 °C to afford the light yellow solid product 5-cyanopyrimidine (174 mg, 78% yield). The product was characterized by 1H NMR (400 MHz, DMSO): δ 9.44 (s, 1H), 9.31 (s, 2H).

References

[1] Patent: WO2012/129564, 2012, A2. Location in patent: Page/Page column 79
[2] Journal of Medicinal Chemistry, 2013, vol. 56, # 10, p. 3783 - 3805
[3] Journal of Organic Chemistry, 2015, vol. 80, # 5, p. 2676 - 2699
[4] Patent: WO2009/148452, 2009, A1. Location in patent: Page/Page column 71

5-CYANOPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-CYANOPYRIMIDINE Suppliers

Canada 1 China 108 Europe 1 Germany 2 India 2 United Kingdom 5 United States 17 Global 136

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Capot Chemical Co., Ltd

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Fax: 0086-571-85864795
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Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
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Chemsky（shanghai）International Co.,Ltd.

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Email: shchemsky@sina.com
Country: China
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Shanghai Ennopharm Co., Ltd.

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SpringPharma Tech Co.,Ltd

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Shanghai HuiKe Trading Co., Ltd.

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NovoChemy Ltd.

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View Lastest Price from 5-CYANOPYRIMIDINE manufacturers

Wuhan Boyuan Import & Export Co., LTD

Product: 5-Cyanopyrimidine CAS NO.40805-79-6 40805-79-6
Price: US $1.00/G
Min. Order: 100G
Purity: 99.9%
Supply Ability: 50000 tons
Release date: 2018-10-30

Dideu Industries Group Limited

Product: 5-CYANOPYRIMIDINE 40805-79-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-14

Career Henan Chemical Co

Product: 5-Pyrimidinecarbonitrile 40805-79-6
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-09

40805-79-6, 5-CYANOPYRIMIDINERelated Search:

2-Pyrimidinecarbonitrile, 5-amino- (9CI) 4-BROMO-PYRIDINE-2-CARBONITRILE 3-Cyanopyridine 2,4-Dichloro-5-cyanopyrimidine 5-Chloro-2-cyanopyridine 2,4-DIAMINOPYRIMIDINE-5-CARBONITRILE 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE 4-Amino-2-(3-pyridyl)pyrimidine-5-carbonitrile 5-Pyrimidinecarbonitrile, 2-chloro- (7CI,8CI) 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE 4-AMINO-2-CHLOROPYRIMIDINE-5-CARBONITRILE 4-AMINO-2-ETHYLSULFANYL-PYRIMIDINE-5-CARBONITRILE 6-BROMO-PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE 4-Cyanopyrimidine 4-AMINO-2-BROMO-5-CYANOPYRIMIDINE,2-BROMO-4-AMINO-5-CYANOPYRIMIDINE 4-AMINO-2-MERCAPTOPYRIMIDINE-5-CARBONITRILE 4-AMINOPYRIMIDINE-5-CARBONITRILE 5-Cyanouracil

5-CYANOPYRIMIDINE

Pyrimidine-5-carbonitrile

5-Pyrimidinecarbonitrile (7CI,9CI)

5-PyriMidinecarbonitrile

5-Cyanopyrimidine, 5-Cyano-1,3-diazine

5-Cyanopyrimidine CAS NO.40805-79-6

5-CYANOPYRIMIDINE ISO 9001：2015 REACH

2-Butyne,3-bromo-

40805-79-6

Heterocycles

Heterocycle-Pyrimidine series

PYRIMIDINE