4-BROMO-PYRIDINE-2-CARBONITRILE
- Product Name
- 4-BROMO-PYRIDINE-2-CARBONITRILE
- CAS No.
- 62150-45-2
- Chemical Name
- 4-BROMO-PYRIDINE-2-CARBONITRILE
- Synonyms
- 4-Bromopicolinonitrile;AURORA 23233;OTAVA-BB BB7110952495;4-BROMO-2-CYANOPYRIDINE;2-Cyano-4-bromopyridine;4-Bromo-2-cyanopyridine,97%;4-BroMo-2-pyridinecarbonitrile;4-BROMO-PYRIDINE-2-CARBONITRILE;2-Pyridinecarbonitrile, 4-bromo-;4-Bromopyridine-2-carbonitrile 98%
- CBNumber
- CB8130312
- Molecular Formula
- C6H3BrN2
- Formula Weight
- 183.01
- MOL File
- 62150-45-2.mol
4-BROMO-PYRIDINE-2-CARBONITRILE Property
- Melting point:
- 82-84°C
- Boiling point:
- 265.3±20.0 °C(Predicted)
- Density
- 1.72±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Solid
- pka
- -2.73±0.10(Predicted)
- color
- Off-White to Light Beige
- InChI
- InChI=1S/C6H3BrN2/c7-5-1-2-9-6(3-5)4-8/h1-3H
- InChIKey
- CZXDCTUSFIKLIJ-UHFFFAOYSA-N
- SMILES
- C1(C#N)=NC=CC(Br)=C1
Safety
- RIDADR
- 3439
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 2933399990
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Acute Tox. 4 Oral
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B686753
- Product name
- 4-Bromopyridine-2-carbonitrile
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 263300
- Product name
- 4-Bromopyridine-2-carbonitrile
- Packaging
- 250mg
- Price
- $333
- Updated
- 2021/12/16
- Product number
- B2866-60
- Product name
- 4-Bromopyridine-2-carbonitrile
- Packaging
- 50mg
- Price
- $347
- Updated
- 2021/12/16
- Product number
- B686753
- Product name
- 4-Bromopyridine-2-carbonitrile
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FB19328
- Product name
- 4-Bromopyridine-2-carbonitrile
- Packaging
- 25g
- Price
- $450
- Updated
- 2021/12/16
4-BROMO-PYRIDINE-2-CARBONITRILE Chemical Properties,Usage,Production
Chemical Properties
Off-Solid
Uses
4-Bromopyridine-2-Carbonitrile is a useful synthetic intermediate.
Synthesis
A. 4-Bromopyridine 1-oxide at room temperature. To a suspension of 4-bromopyridine hydrochloride (5.0 g, 25.9 mmol) in dichloromethane (50 mL) was added triethylamine (2.62 g, 25.9 mmol). After stirring for 0.5 h, 3-chloroperoxybenzoic acid (4.46 g, 25.9 mmol) was added in batches, and the reaction mixture was stirred at room temperature for 5 h. The solution was washed with saturated aqueous sodium thiosulfate (30 mL), saturated aqueous sodium carbonate (30 mL), and brine (30 mL), and dried over sodium sulfate. The solvent was removed under reduced pressure to give the crude product, which was purified on silica gel chromatography (eluting with 50-100% ethyl acetate in methanol) to give 4-bromopyridine 1-oxide, solid (2.1 g, 44.8% yield).
B.4-Bromopyridine-2-carbonitrile. A mixture of 4-bromopyridine 1-oxide (2.0 g, 11.56 mmol), trimethylmethylsilyl cyanide (3.43 g, 34.68 mmol) and triethylamine (2.34 g, 23.12 mmol) in acetonitrile (10 mL) was stirred under nitrogen at 110 C for 3 h. The reaction mixture was concentrated under reduced pressure and the residue was purified on a silica gel column (with petroleum ether eluting with 20% ethyl acetate in petroleum ether) to afford 4-bromopyridine-2-carbonitrile (1.52 g, 72.4% yield).4-BROMO-PYRIDINE-2-CARBONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-BROMO-PYRIDINE-2-CARBONITRILE manufacturers
- Product
- 4-Bromopyridine-2-carbonitrile 62150-45-2
- Price
- US $1.10-9.90/KG
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 100KG
- Release date
- 2025-08-20
- Product
- 4-BROMO-PYRIDINE-2-CARBONITRILE 62150-45-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-20
- Product
- 4-Bromopyridine-2-carbonitrile 62150-45-2
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-12