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4-BROMO-PYRIDINE-2-CARBONITRILE

Product Name
4-BROMO-PYRIDINE-2-CARBONITRILE
CAS No.
62150-45-2
Chemical Name
4-BROMO-PYRIDINE-2-CARBONITRILE
Synonyms
4-Bromopicolinonitrile;AURORA 23233;OTAVA-BB BB7110952495;4-BROMO-2-CYANOPYRIDINE;2-Cyano-4-bromopyridine;4-Bromo-2-cyanopyridine,97%;4-BroMo-2-pyridinecarbonitrile;4-BROMO-PYRIDINE-2-CARBONITRILE;2-Pyridinecarbonitrile, 4-bromo-;4-Bromopyridine-2-carbonitrile 98%
CBNumber
CB8130312
Molecular Formula
C6H3BrN2
Formula Weight
183.01
MOL File
62150-45-2.mol
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4-BROMO-PYRIDINE-2-CARBONITRILE Property

Melting point:
82-84°C
Boiling point:
265.3±20.0 °C(Predicted)
Density 
1.72±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Solid
pka
-2.73±0.10(Predicted)
color 
Off-White to Light Beige
InChI
InChI=1S/C6H3BrN2/c7-5-1-2-9-6(3-5)4-8/h1-3H
InChIKey
CZXDCTUSFIKLIJ-UHFFFAOYSA-N
SMILES
C1(C#N)=NC=CC(Br)=C1
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Safety

RIDADR 
3439
HazardClass 
6.1
PackingGroup 
HS Code 
2933399990
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
B686753
Product name
4-Bromopyridine-2-carbonitrile
Packaging
250mg
Price
$45
Updated
2021/12/16
Usbiological
Product number
263300
Product name
4-Bromopyridine-2-carbonitrile
Packaging
250mg
Price
$333
Updated
2021/12/16
Usbiological
Product number
B2866-60
Product name
4-Bromopyridine-2-carbonitrile
Packaging
50mg
Price
$347
Updated
2021/12/16
TRC
Product number
B686753
Product name
4-Bromopyridine-2-carbonitrile
Packaging
1g
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB19328
Product name
4-Bromopyridine-2-carbonitrile
Packaging
25g
Price
$450
Updated
2021/12/16
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4-BROMO-PYRIDINE-2-CARBONITRILE Chemical Properties,Usage,Production

Chemical Properties

Off-Solid

Uses

4-Bromopyridine-2-Carbonitrile is a useful synthetic intermediate.

Synthesis

A. 4-Bromopyridine 1-oxide at room temperature. To a suspension of 4-bromopyridine hydrochloride (5.0 g, 25.9 mmol) in dichloromethane (50 mL) was added triethylamine (2.62 g, 25.9 mmol). After stirring for 0.5 h, 3-chloroperoxybenzoic acid (4.46 g, 25.9 mmol) was added in batches, and the reaction mixture was stirred at room temperature for 5 h. The solution was washed with saturated aqueous sodium thiosulfate (30 mL), saturated aqueous sodium carbonate (30 mL), and brine (30 mL), and dried over sodium sulfate. The solvent was removed under reduced pressure to give the crude product, which was purified on silica gel chromatography (eluting with 50-100% ethyl acetate in methanol) to give 4-bromopyridine 1-oxide, solid (2.1 g, 44.8% yield).

B.4-Bromopyridine-2-carbonitrile. A mixture of 4-bromopyridine 1-oxide (2.0 g, 11.56 mmol), trimethylmethylsilyl cyanide (3.43 g, 34.68 mmol) and triethylamine (2.34 g, 23.12 mmol) in acetonitrile (10 mL) was stirred under nitrogen at 110 C for 3 h. The reaction mixture was concentrated under reduced pressure and the residue was purified on a silica gel column (with petroleum ether eluting with 20% ethyl acetate in petroleum ether) to afford 4-bromopyridine-2-carbonitrile (1.52 g, 72.4% yield).

4-BROMO-PYRIDINE-2-CARBONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BROMO-PYRIDINE-2-CARBONITRILE Suppliers

Shanghai Toplab Chemical Co., Ltd.
Tel
021-31137757-00; 18121466954
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021-64902762
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28328681@qq.com
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China
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Nanjing Wanpu Pharmaceutical Technology Co.,Ltd
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13814527050; 13814527050
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3773605130@qq.com
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
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86-21-61259102
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market03@meryer.com
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China
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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Energy Chemical
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sales8178@energy-chemical.com
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JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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86-021-50426522,50426273
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sales@jingyan-chemical.com
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China
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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sales@chemreagents.com
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United States
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Tetranov Biopharm
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13526569071
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sales@leadmedpharm.com
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China
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Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
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021-50795055
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marketing@accelachem.com
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China
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View Lastest Price from 4-BROMO-PYRIDINE-2-CARBONITRILE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
4-Bromopyridine-2-carbonitrile 62150-45-2
Price
US $1.10-9.90/KG
Min. Order
1KG
Purity
99%min
Supply Ability
100KG
Release date
2025-08-20
Dideu Industries Group Limited
Product
4-BROMO-PYRIDINE-2-CARBONITRILE 62150-45-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-20
Shaanxi Dideu Medichem Co. Ltd
Product
4-Bromopyridine-2-carbonitrile 62150-45-2
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-12

62150-45-2, 4-BROMO-PYRIDINE-2-CARBONITRILERelated Search:


  • AURORA 23233
  • 4-BROMO-PYRIDINE-2-CARBONITRILE
  • 4-BROMO-2-CYANOPYRIDINE
  • OTAVA-BB BB7110952495
  • 4-Bromopicolinonitrile
  • 4-Bromopyridine-2-carbonitrile 98%
  • 4-Bromo-2-cyanopyridine, 4-Bromopicolinonitrile
  • 4-BroMo-2-pyridinecarbonitrile
  • 2-Cyano-4-bromopyridine
  • 2-Pyridinecarbonitrile, 4-bromo-
  • 4-Bromo-2-cyanopyridine,97%
  • 4-BROMO-PYRIDINE-2-CARBONITRILE ISO 9001:2015 REACH
  • 62150-45-2
  • intermediate
  • 6
  • Heterocycles
  • Nucleotides
  • pharmacetical
  • Heterocyclic Compounds
  • Bases & Related Reagents