ChemicalBook > CAS DataBase List > Cyclopropanecarboxylic acid
Cyclopropanecarboxylic acid
Description Uses- Product Name
- Cyclopropanecarboxylic acid
- CAS No.
- 1759-53-1
- Chemical Name
- Cyclopropanecarboxylic acid
- Synonyms
- Cyclopropionic acid;cyclopropanecarboxylic;CYCLOPROPYL CARBOXYLIC ACID;CPC-ACID;Cyclopropane c;Cyclopropanic acid;Carboxycyclopropane;RARECHEM AL BO 0005;Ring propyl forMate;Olapali impurity 20
- CBNumber
- CB8343293
- Molecular Formula
- C4H6O2
- Formula Weight
- 86.09
- MOL File
- 1759-53-1.mol
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Cyclopropanecarboxylic acid Property
- Melting point:
- 14-17 °C (lit.)
- Boiling point:
- 182-184 °C (lit.)
- Density
- 1.081 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.438(lit.)
- Flash point:
- 161 °F
- storage temp.
- 2-8°C
- solubility
- soluble in Chloroform, Ethyl Acetate
- form
- Liquid
- pka
- 4.83(at 25℃)
- color
- Clear colorless to light yellow
- PH
- 3 (10g/l, H2O, 22℃)
- BRN
- 969839
- InChIKey
- YMGUBTXCNDTFJI-UHFFFAOYSA-N
- LogP
- 0.630
- CAS DataBase Reference
- 1759-53-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Cyclopropanecarboxylic acid(1759-53-1)
- EPA Substance Registry System
- Cyclopropanecarboxylic acid (1759-53-1)
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Safety
- Hazard Codes
- C,Xi
- Risk Statements
- 34-22
- Safety Statements
- 26-36/37/39-45-27
- RIDADR
- UN 3265 8/PG 2
- WGK Germany
- 3
- RTECS
- GZ1100000
- Hazard Note
- Irritant/Corrosive
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29162000
- Toxicity
- mouse,LD50,intraperitoneal,172mg/kg (172mg/kg),Journal of Pharmacy and Pharmacology. Vol. 21, Pg. 85, 1969.
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
P405Store locked up.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C116602
- Product name
- Cyclopropanecarboxylic acid
- Purity
- 95%
- Packaging
- 25g
- Price
- $47.2
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C116602
- Product name
- Cyclopropanecarboxylic acid
- Purity
- 95%
- Packaging
- 100g
- Price
- $65.2
- Updated
- 2024/03/01
TCI Chemical
- Product number
- C0387
- Product name
- Cyclopropanecarboxylic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25mL
- Price
- $25
- Updated
- 2024/03/01
TCI Chemical
- Product number
- C0387
- Product name
- Cyclopropanecarboxylic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 100mL
- Price
- $67
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- A14215
- Product name
- Cyclopropanecarboxylic acid, 98%
- Packaging
- 50g
- Price
- $46.65
- Updated
- 2024/03/01
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Cyclopropanecarboxylic acid Chemical Properties,Usage,Production
Description
Cyclopropanecarboxylic acid is a kind of organic acid. It is a clear liquid used as an intermediate for agrochemicals, pharmaceuticals, and other organic synthesis for the applications of electronics, chemicals, polymer additives, coatings, adhesives, surfactants, and other applications1. Moreover, its derivatives of are used against parasites in plants and animals. For example, the alkynyl esters of cyclopropane-carboxylic acid are used as pesticides. Similarly, cyclopropane carboxylic acid esters containing a polyhalogenated substituent are used as fungicides. The ethyl derivative is reagent used in the addition of cyclopropane and can act as annulation reagent for the conversion of aromatics to 2-methylindanones under Friedel-Crafts conditions2.
Uses
Cyclopropanecarboxylic acid is a monocarboxylic acid and a member of cyclopropanes. It is a conjugate acid of a cyclopropanecarboxylate.
Chemical Properties
clear colourless to light yellow liquid
Uses
Cyclopropanecarboxylic Acid is used as a reagent in the synthesis of substituted 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors. Also used as a reagent in the synthesis of 2-alkyloxazoles as potent and selective PI4KIIIb inhibitors demonstrating inhibition of HCV replication.
Definition
ChEBI: Cyclopropanecarboxylic acid is a monocarboxylic acid and a member of cyclopropanes. It is a conjugate acid of a cyclopropanecarboxylate.
Preparation
Cyclopropanecarboxylic acid has been prepared by the hydrolysis of cyclopropyl cyanide, although it is unnecessary to isolate the nitrile; by heating cyclopropanedicarboxylic acid; and by the action of alkali on ethyl γ-chlorobutyrate.7 The last two methods do not appear to be of practical importance. The oxidation of cyclopropyl methyl ketone with sodium hypobromite is reported to be an excellent preparative method for this acid.
Org. Synth. 1944, 24, 36
DOI: 10.15227/orgsyn.024.0036
Cyclopropanecarboxylic acid Preparation Products And Raw materials
Raw materials
Methyl 4-chlorobutyrate
Zinc chloride
4-Chlorobutyryl chloride
4-Chlorobutyronitrile
Butyl butyrate
Gamma Butyrolactone
Preparation Products
3-(1，2，2，2-tetrabromoethyl)-2，2-dimethyl cyclo-propane carboxylic acid
CYCLOPROTHRIN
Cilastatin
Cyclopropanecarbonyl Chloride
(1R-cis)-3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropane carboxylic acid
Deltamethrin
1-AMINO-CYCLOPROPANEMETHANOL
Ethyl 2,2,3,3-tetramethylcyclopropane-carboxylate
(Bromomethyl)cyclopropane
Permethrin
5-CYCLOPROPYL-2H-PYRAZOL-3-YLAMINE
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View Lastest Price from Cyclopropanecarboxylic acid manufacturers
Hebei Yanxi Chemical Co., Ltd.
- Product
- Cyclopropanecarboxylic acid 1759-53-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99.00%
- Supply Ability
- 20tons
- Release date
- 2023-09-12
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- Cyclopropanecarboxylic acid 1759-53-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97%
- Supply Ability
- 500kgs/month
- Release date
- 2021-10-28
Hebei Mojin Biotechnology Co., Ltd
- Product
- Cyclopropanecarboxylic acid 1759-53-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-07-24
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