N,N-Dimethylglycine hydrochloride
- Product Name
- N,N-Dimethylglycine hydrochloride
- CAS No.
- 2491-06-7
- Chemical Name
- N,N-Dimethylglycine hydrochloride
- Synonyms
- N,N-DIMETHYLGLYCINE HCL;DIMETHYL GLYCINE HYDROCHLORIDE;2-(DIMETHYLAMINO)ACETIC ACID HYDROCHLORIDE;DMG HYDROCHLORIDE;H-GLY(2ME)-OH HCL;DIMETHYLGLYCINE HCL;IFLAB-BB F1929-1772;N,N-DIMETHYL-GLY-OH HCL;N,N-DiMethyl-d3-glycine HCl;N,N-dimethylglycinium chloride
- CBNumber
- CB8360829
- Molecular Formula
- C4H10ClNO2
- Formula Weight
- 139.58
- MOL File
- 2491-06-7.mol
N,N-Dimethylglycine hydrochloride Property
- Melting point:
- 189-194 °C(lit.)
- Boiling point:
- 397.74℃[at 101 325 Pa]
- Density
- 1.326[at 20℃]
- vapor pressure
- 0Pa at 25℃
- storage temp.
- Store below +30°C.
- solubility
- DMSO: 10 mg/ml; PBS (pH 7.2): 10 mg/ml
- form
- Crystalline Powder
- color
- White
- Odor
- Slight to none
- Water Solubility
- 100 g/L (20 ºC)
- Sensitive
- Hygroscopic
- Merck
- 14,3244
- BRN
- 3910578
- LogP
- -0.3
- CAS DataBase Reference
- 2491-06-7(CAS DataBase Reference)
- EPA Substance Registry System
- Glycine, N,N-dimethyl-, hydrochloride (2491-06-7)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- D6382
- Product name
- N,N-Dimethylglycine hydrochloride
- Packaging
- 5G
- Price
- $58.2
- Updated
- 2025/07/31
- Product number
- D6382
- Product name
- N,N-Dimethylglycine hydrochloride
- Packaging
- 25G
- Price
- $254
- Updated
- 2025/07/31
- Product number
- 8.18448
- Product name
- N,N-Dimethylglycine hydrochloride
- Purity
- for synthesis
- Packaging
- 10g
- Price
- $108
- Updated
- 2025/07/31
- Product number
- D0728
- Product name
- N,N-Dimethylglycine Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $92
- Updated
- 2025/07/31
- Product number
- 270751
- Product name
- N,N-Dimethylglycine Hcl
- Packaging
- 5g
- Price
- $280
- Updated
- 2021/12/16
N,N-Dimethylglycine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
white crystalline powder
Uses
N,N-Dimethylglycine (DMG) is a natural N-methylated glycine that is used in comparative analysis with other N-methylated glycines such as sarcosine and βine. Used in the development of glycine-based ionic liquids and emulsifiers. Also it is potentially useful as a biomarker of protein degradation in COPD patients. DMG is used as a substrate to identify, differentiate and characterize amino acid methyltransferase(s).
Flammability and Explosibility
Not classified
Biochem/physiol Actions
N,N-Dimethylglycine (DMG) is a natural N-methylated glycine that is used in comparative analysis with other N-methylated glycines such as sarcosine and βine. N,N-Dimethylglycine is used in the development of glycine-based ionic liquids and emulsifiers. N,N-Dimethylglycine is potentially useful as a biomarker of protein degradation in COPD patients. DMG is used as a substrate to identify, differentiate and characterize amino acid methyltransferase(s).
in vivo
N,N-Dimethylglycine (30-100 mg/kg; intraperitoneal injection; twice a day; 14 days) hydrochloride prevents the behavioral abnormalities and synaptic dysfunction induced by repeated drug exposure in male ICR mice[1].
N,N-Dimethylglycine (12 mg/0.3 mL sterile saline; gavage; single dose; subcutaneous injection 1 hour later) hydrochloride improves the histological morphology of the small intestine, enhances the antioxidant system, reduces oxidative damage, and increases the expression of antioxidant-related genes in male Kunming mice[2].
N,N-Dimethylglycine (12 mg/0.3 mL sterile saline; gavage; twice a day; 28 days) hydrochloride increases the body weight, the organ proportion of the liver and spleen, enhances the antioxidant capacity of serum and liver, and reduces the activities of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) as well as the malondialdehyde (MDA) content in serum and liver in male Kunming mice[3].
N,N-Dimethylglycine (12 mg/0.3 mL sterile saline; gavage; twice a day; 28 days) hydrochloride reduces the serum ALT and AST contents, the ROS level in hepatic mitochondria, and increases the antioxidant capacity of hepatic mitochondria and the mitochondrial membrane potential (MMP) level in male Kunming mice with Lipopolysaccharides (LPS) (HY-D1056)-induced oxidative stress model[3].
| Animal Model: | Male ICR mice (body weight 10-12 g, 3-week- old) + Repeated drug exposure (20 mg/kg, i.p., twice daily for 14 days)[1]. |
| Dosage: | 30 mg/kg, 100 mg/kg |
| Administration: | Intraperitoneal injection, 20 min prior to each drug injection, twice a day, 14 days. |
| Result: | Prevented the drug-induced memory impairments in novel location recognition test (NLRT) and novel object recognition test (NORT), social withdrawal in reciprocal social interaction test, and enhanced head twitch response induced by serotonergic hallucinogen. |
| Animal Model: | Male Kunming mice (weight 20-25 g, 40 days old) + Indomethacin injection (10 mg/kg BW)[2]. |
| Dosage: | 12 mg/0.3 mL sterile saline |
| Administration: | Orally gavage; single dose; and then subcutaneous injection 1 hour later. |
| Result: | Improved the histological morphology of the small intestine. Enhanced the antioxidant system, reduced oxidative damage, and increased the expression of antioxidant-related genes in the small intestine and its mitochondria compared with the indomethacin-treated group2. |
| Animal Model: | Male Kunming mice (weight 20-25 g, 40 days old) + Lipopolysaccharides (LPS) injection (100 μg/kg body weight)[3]. |
| Dosage: | 12 mg/0.3 mL sterile saline |
| Administration: | Orally gavage; twice a day; 28 days. |
| Result: | Significantly decreased the serum ALT and AST content, ROS level, and expression of liver antioxidant gene MnSOD, Gpx1, Sirt1. Significantly increased the hepatic mitochondrial antioxidant capacity (MnSOD, GSH, GPx, GR) and MMP level compared with the LPS-treated group. |
IC 50
Human Endogenous Metabolite
N,N-Dimethylglycine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
N,N-Dimethylglycine hydrochloride Suppliers
- Tel
- --
- Fax
- --
- chemcontrol@nextra.sk
- Country
- Slovakia
- ProdList
- 6700
- Advantage
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View Lastest Price from N,N-Dimethylglycine hydrochloride manufacturers
- Product
- N,N-Dimethylglycine hydrochloride 2491-06-7
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1000kg
- Release date
- 2021-12-09
- Product
- N,N-Dimethylglycine hydrochloride 2491-06-7
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-07
- Product
- N,N-Dimethylglycine hydrochloride 2491-06-7
- Price
- US $50.00-28.00/KG
- Min. Order
- 1KG
- Purity
- 99% HPLC
- Supply Ability
- 5Tons
- Release date
- 2021-12-14