BLASTICIDIN S HYDROCHLORIDE

Product Name: BLASTICIDIN S HYDROCHLORIDE
CAS No.: 3513-03-9
Chemical Name: BLASTICIDIN S HYDROCHLORIDE
Synonyms: BLASTICIDIN S HCL;Blasticidine S HCl;BLASTICIDIN S 50MG;Miewen S hydrochloride;Blasticidin S (10 mg/ml);BLASTICIDIN S HYDROCHLORIDE;BLASTICIDINE S HYDROCHLORIDE;Blasticidin S (10 mg/mL in Solution);Blasticidine S hydrochloride solution;BLASTICIDIN S HYDROCHLORIDE USP/EP/BP
CBNumber: CB8383972
Molecular Formula: C17H27ClN8O5
Formula Weight: 458.9
MOL File: 3513-03-9.mol

More

Less

BLASTICIDIN S HYDROCHLORIDE Property

Melting point:: 224-225 °C (decomp)
storage temp.: −20°C
solubility: Soluble in Water (greater than 25 mg/ml)
form: Liquid
color: White
Water Solubility: Soluble in water. Insoluble in organic solvents.
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.

More

Less

Safety

Hazard Codes: T+
Risk Statements: 28
Safety Statements: 28-36/37-45
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
F: 1-10
HazardClass: 6.1
HS Code: 29349990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 203350
Product name: Blasticidin S, Hydrochloride, Streptomyces griseochromogenes - CAS 589205 - Calbiochem
Packaging: 25mg
Price: $216
Updated: 2024/03/01

Sigma-Aldrich

Product number: 203351-M
Product name: Blasticidin S, Hydrochloride, Streptomyces sp., Sterile-Filtered Aqueous Solution, Cell Culture-Tested - CAS 589205 - Calbiochem
Purity: sterile; sterile-filtered, suitable for cell culture
Packaging: 10ml
Price: $583
Updated: 2022/05/15

Sigma-Aldrich

Product number: 203351-M
Product name: Blasticidin S, Hydrochloride, Streptomyces sp., Sterile-Filtered Aqueous Solution, Cell Culture-Tested - CAS 589205 - Calbiochem
Purity: sterile; sterile-filtered, suitable for cell culture
Packaging: 203351-10ML
Price: $583
Updated: 2022/05/15

Sigma-Aldrich

Product number: 15205
Product name: Blasticidine S hydrochloride
Packaging: 25MG
Price: $173
Updated: 2022/05/15

Sigma-Aldrich

Product number: 15205
Product name: Blasticidine S hydrochloride
Packaging: 100MG
Price: $476
Updated: 2022/05/15

More

Less

BLASTICIDIN S HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Blasticidin S HCl (3513-03-9) is a peptidyl nucleoside antibiotic inhibiting protein synthesis in bacteria and eukaryotes.1?Inhibits translation by trapping deformed tRNA on the ribosome.1?The ABC-type transporter NppA1A2BCD is required for uptake of blasticidin S and other peptidyl nucleoside antibiotics in?Pseudomonas aeruginosa?PA14.2?Selection agent for bis, bsr and bsd transformed cells.3,4

Chemical Properties

White powder

Uses

Inhibits protein synthesis and induces apoptosis. Used to study protein synthesis at the level of peptide bond formation.

Uses

Blasticidin S hydrochloride is used to inhibit protein synthesis in prokaryotic and eukaryotic organisms. It also induces apoptosis.

Uses

Blasticidin S hydrochloride is a salt of blasticidin S, an amphoteric nucleoside produced by several species of Streptomyces, first reported in the late 1950s. Blasticidin S hydrochloride was originally isolated fby acetone precipitation. For historical reasons only the salt has been routinely available to researchers. Both the salt and free base are freely water soluble. Blasticidin S is an antifungal agent with particularly potent activity against the rice pathogen, Piricularia oryzae, for which it was used commercially for some time in Japan. Blasticidin S inhibits protein synthesis and is active against bacteria, tumour cell lines and nematodes. More recently, blasticidin S has been used as a marker for strain manipulations.

General Description

Nucleoside antibiotic that specifically inhibits protein synthesis in both prokaryotes and eukaryotes. Suitable for selection of cells carrying plasmids conferring blasticidin resistance. Blasticidin resistance is conferred by the blasticidin S deaminase gene (bsr) that converts blastisidin S to a nontoxic deaminohydroxy derivative.

storage

Store at -20°C

References

1) Svidritskiy?et al., (2013),?Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome;?Proc. Natl. Acad. Sci. USA?110?12283 2) Pletzer?et al.?(2015),?The Pseudomonas aeruginosa PA14 ABC Transporter NppA1A2BCD is Required for Uptake of Peptidyl Nucleoside Antibiotics; J. Bacteriol.?197?2217 3) Asada?et al.?(2015),?Transfection of Babesia bovis by Double Selection with WR99210 and Blasticidin-S and Its Application for Functional Analysis of Thioredoxin Peroxidase-1; PLoS One,?10?e0125993 4) Garg and Qadri (2010),?Hemoglobin transforms anti-inflammatory Salmonella typhi virulence polysaccharide into a TLR-2 agonist; J. Immunol.?184?5980

BLASTICIDIN S HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BLASTICIDIN S HYDROCHLORIDE Suppliers

China 96 France 1 Germany 4 India 4 Japan 1 Switzerland 3 United Kingdom 8 United States 24 Global 141

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

BOC Sciences

Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19741
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Focus Biomolecules

Tel: --
Fax: --
Email: sales@focusbiomolecules.com
Country: United States
ProdList: 1284
Advantage: 58

EBRATOR BIOCHEMICALS,INC.

Tel: --
Fax: --
Email: sales@ebtbio.com
Country: United States
ProdList: 577
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Creative Enzymes

Tel: --
Fax: --
Email: info@creative-enzymes.com
Country: United States
ProdList: 6057
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

TOKU-E Company

Tel: --
Fax: --
Email: info@toku-e.com
Country: United States
ProdList: 320
Advantage: 50

Selleck Chemicals LLC

Tel: --
Fax: --
Email: info@selleckchem.com
Country: United States
ProdList: 824
Advantage: 60

Anvia Chemicals, LLC

Tel: --
Fax: --
Email: sales@anviachem.com
Country: United States
ProdList: 3933
Advantage: 0

Chem-Impex International, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6730
Advantage: 64

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

Kainic.com

Tel: --
Fax: --
Email: info@Kainic.com
Country: United States
ProdList: 330
Advantage: 38

EMD Biosciences, Inc.

Tel: --
Fax: --
Email: technical@calbiochem.com
Country: United States
ProdList: 6529
Advantage: 66

INDOFINE Chemical Company, Inc.

Tel: --
Fax: --
Email: chemical@indofinechemical.com
Country: United States
ProdList: 6176
Advantage: 69

LKT Laboratories, Inc.

Tel: --
Fax: --
Email: info@lktlabs.com
Country: United States
ProdList: 2164
Advantage: 64

MP Biomedicals, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6561
Advantage: 81

3513-03-9, BLASTICIDIN S HYDROCHLORIDERelated Search:

Clindamycin hydrochloride Cefotaxime sodium MALFORMINC PHLEOMYCIN Geneticin Hygromycin B Ketanserin 5-Azacytidine WAY100635 CHIR-99021 Barasertib (AZD1152-HQPA) BLASTICIDIN S (S)-2-AMINO-BUT-3-EN-1-OL HYDROCHLORIDE L-ALLOISOTHREONINE HCL H-BETA-ALA-BETA-ALA-OH Demethylblasticidin S BLASTICIDIN S HYDROCHLORIDE BLASTICIDIN S HYDROCHLORIDE,BLASTICIDIN S, HYDROCHLORIDE, STREPTOMYCES GRISEOCHROMOGENES

BLASTICIDINE S HYDROCHLORIDE

BLASTICIDIN S HCL

BLASTICIDIN S HYDROCHLORIDE

BLASTICIDIN S, HYDROCHLORIDE, STREPTOMYCES GRISEOCHROMOGENES

Blasticidine S hydrochloride,Blasticidin S

(S)-4-[[3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-Hex-2-enopyranuronic acid,monohydrochloride

Blasticidine S HCl

Blasticidine S hydrochloride solution

Blasticidine S hydrochloride solution,1000ppm

Blasticidin S hydrochloride≥ 98% (HPLC)

Blasticidine S hydrochloride Solution, 100ppm

(2S,3S,6R)-3-[[(3R)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid,hydrochloride

Blasticidin S, Hydrochloride, Streptomyces sp., Sterile-Filtered Aqueous Solution, Cell Culture-Tested - CAS 589205 - Calbiochem

(S)-4-[[3-Amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-hex-2-enopyranuronic acid hydrochloride

BLASTICIDIN S 50MG

BLASTICIDIN S HYDROCHLORIDE USP/EP/BP

Blasticidin S Hydrochloride for cell culture, 98%, Endotoxin (BET) 0.05EU/mg

Blasticidin S (10 mg/ml)

(2S,3S,6R)-6-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-((S)-3-amino-5-(1-methylguanidino)pentanamido)-3,6-dihydro-2H-pyran-2-carboxylic acid hydrochloride

Blasticidin S (10 mg/mL in Solution)

Miewen S hydrochloride

BlasticidineSHCl in Acetonitrile:Water=1:1

3513-03-9

C17H26N8O5HCl

C17H27ClN8O5

BioChemical

Antibiotics A-F

Antibiotics A to Z

Antibiotics

Inhibitors

antibiotic