3-METHOXYPYRIDINE Property

Melting point:

203 °C

Boiling point:

65 °C/15 mmHg (lit.)

Density 

1.083 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.518(lit.)

Flash point:

159 °F

storage temp. 

Inert atmosphere,Room Temperature

form 

Liquid

pka

4.78(at 25℃)

color 

Clear colorless to slightly yellow

InChI

InChI=1S/C6H7NO/c1-8-6-3-2-4-7-5-6/h2-5H,1H3

InChIKey

UMJSCPRVCHMLSP-UHFFFAOYSA-N

SMILES

C1=NC=CC=C1OC

LogP

0.990

NIST Chemistry Reference

Pyridine, 3-methoxy-(7295-76-3)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39-36

WGK Germany 

3

HS Code 

29333999

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

3-METHOXYPYRIDINE Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to slightl yellow liquid

Uses

3-Methoxypyridine was used in the study of structure-activity relationships of pyridines as Sir2 histone/protein deacetylase inhibitors.

Uses

3-Methoxypyridine may be employed as a catalyst for the addition reaction of various 1,2-acyclic diones to activated acetylenic esters.

General Description

3-Methoxypyridine is a substituted pyridine. Kinetics of the oxidation of 3-methoxypyridine mediated by sulphate radicals has been investigated by flash photolysis of peroxodisulphate, S₂O₈^2-. Ortho lithiation of 3-methoxypyridine has been studied using mesityllithium as the metalating base.