KETANSERIN TARTRATE
- Product Name
- KETANSERIN TARTRATE
- CAS No.
- 83846-83-7
- Chemical Name
- KETANSERIN TARTRATE
- Synonyms
- kjk-945;R 41468;R41468 tartrate;Ketanserin Tartrat;Ketanserinetartrate;KETANSERIN TARTRATE;R 41468 TARTRATE SALT;quinazoline-2,4(1H,3H);KETANSERIN TARTRATE SALT;3-(2-(4-(4-Fluorobenzoyl)
- CBNumber
- CB8415888
- Molecular Formula
- C26H28FN3O9
- Formula Weight
- 545.52
- MOL File
- 83846-83-7.mol
KETANSERIN TARTRATE Property
- Melting point:
- 183~186℃
- storage temp.
- 2-8°C
- solubility
- ethanol: 3.3mg/mL
- form
- solid
- color
- white
- Water Solubility
- Soluble to 10 mM in water
- CAS DataBase Reference
- 83846-83-7(CAS DataBase Reference)
Safety
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 22-36/37/39-45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- VA1411195
- HazardClass
- 6.1
- HS Code
- 29335990
- Toxicity
- LD50 oral in rat: 129mg/kg
N-Bromosuccinimide Price
- Product number
- S006
- Product name
- Ketanserin (+)-tartrate salt
- Purity
- ≥97%, solid
- Packaging
- 10mg
- Price
- $87.6
- Updated
- 2024/03/01
- Product number
- S006
- Product name
- Ketanserin (+)-tartrate salt
- Purity
- ≥97%, solid
- Packaging
- 50mg
- Price
- $279
- Updated
- 2024/03/01
- Product number
- 5.06271
- Product name
- Ketanserin Tartrate - CAS 83846-83-7 - Calbiochem
- Packaging
- 50MG
- Price
- $126
- Updated
- 2024/03/01
- Product number
- J62798
- Product name
- Ketanserin tartrate, 98+%
- Packaging
- 250mg
- Price
- $390.65
- Updated
- 2024/03/01
- Product number
- 22058
- Product name
- Ketanserin (tartrate)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $81
- Updated
- 2024/03/01
KETANSERIN TARTRATE Chemical Properties,Usage,Production
Description
Ketanserin is a potent antagonist of the serotonin (5-HT) receptor that is selective for 5-HT2 (IC50 = 6.3 nM; Ki = 2.1 nM). It has no activity at 5-HT1 receptors but does have activity at histamine type 1, α1-adrenergic, and dopamine receptors with Ki values of 10, 10, and 220 nM, respectively. Ketanserin induces dose-dependent inhibition of contractile responses to 5-HT in isolated rat caudal artery, canine basilar, carotid, coronary and gastrosplenic arteries, and canine gastrosplenic and saphenous veins. Ketanserin (10 mg/kg/day) significantly decreases blood pressure (BP), blood pressure variability (BPV), and hypertensive organ damage in spontaneously hypertensive rats. Formulations containing ketanserin have been used to treat hypertension in early-onset preeclampsia.
Uses
coccidiostat
Uses
Selective 5-HT2A serotonin receptor antagonist
Biological Activity
Selective 5-HT 2A serotonin receptor antagonist; can also be used to discriminate between 5-HT 1D and 5-HT 1B receptor subtypes.
Biochem/physiol Actions
Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.
storage
Room temperature
KETANSERIN TARTRATE Preparation Products And Raw materials
Raw materials
Preparation Products
KETANSERIN TARTRATE Suppliers
View Lastest Price from KETANSERIN TARTRATE manufacturers
- Product
- Ketanserin tartrate 83846-83-7
- Price
- US $0.00/Kg/Bag
- Min. Order
- 10g
- Purity
- 99%min
- Supply Ability
- 10kg
- Release date
- 2021-08-14
- Product
- KETANSERIN TARTRATE 83846-83-7
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000tons
- Release date
- 2023-06-19
- Product
- Ketanserin Tartrate 83846-83-7
- Price
- US $50.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 9000kg/per week
- Release date
- 2021-06-08