4-Aminobenzohydrazide

ChemicalBook > CAS DataBase List > 4-Aminobenzohydrazide

4-Aminobenzohydrazide

Product Name: 4-Aminobenzohydrazide
CAS No.: 5351-17-7
Chemical Name: 4-Aminobenzohydrazide
Synonyms: 4-POBN;4NPhCON2;aminostimil;WLN: ZNUYQR DZ;ambenhydrazide;Amben hydrazide;TIMTEC-BB SBB007555;N,4-Diaminobenzamide;P-AMINOBENZHYDRAZIDE;4-AMINOBENZHYDRAZIDE
CBNumber: CB8434256
Molecular Formula: C7H9N3O
Formula Weight: 151.17
MOL File: 5351-17-7.mol

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4-Aminobenzohydrazide Property

Melting point:: 225-227 °C (lit.)
Boiling point:: 273.17°C (rough estimate)
Density: 1.2100 (rough estimate)
refractive index: 1.5860 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMF: 10 mg/ml; DMSO: 14 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
pka: 13.05±0.10(Predicted)
form: Crystals or Powder
color: White or beige
Water Solubility: Soluble in DMSO (10 mg/ml), dilute acids, and water (partly miscible).
BRN: 639053
CAS DataBase Reference: 5351-17-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 4-amino-, hydrazide(5351-17-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: DG2580000
HazardClass: IRRITANT
HS Code: 29280000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A41909
Product name: 4-Aminobenzoic hydrazide
Purity: 95%
Packaging: 10g
Price: $54.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 475944
Product name: Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem
Packaging: 1g
Price: $96.7
Updated: 2024/03/01

TCI Chemical

Product number: A1211
Product name: 4-Aminobenzohydrazide
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $131
Updated: 2024/03/01

Alfa Aesar

Product number: A10963
Product name: 4-Aminobenzhydrazide, 98%
Packaging: 100g
Price: $160
Updated: 2021/12/16

Alfa Aesar

Product number: A10963
Product name: 4-Aminobenzhydrazide, 98%
Packaging: 25g
Price: $53.9
Updated: 2021/12/16

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4-Aminobenzohydrazide Chemical Properties,Usage,Production

Description

4-Aminobenzoic acid hydrazide (4-ABAH) is an irreversible inhibitor of myeloperoxidase (MPO; IC₅₀ = 0.3 μM). It reduces the production of hypochlorous acid (HOCl) induced by opsonized zymosan or phorbol 12-myristate 13-acetate (PMA; ) in isolated human neutrophils with IC₅₀ values of 16 and 2.2 μM, respectively. 4-ABAH inhibits PMA-induced formation of neutrophil extracellular traps (NETs) in the same cells. It reduces infarct volume and the severity of neurological deficits, as well as increases survival, in a mouse model of cerebral ischemia induced by transient middle cerebral artery occlusion (MCAO) when administered at a dose of 40 mg/kg twice per day.

Chemical Properties

White or beige crystals or powder

Uses

4-Aminobenzhydrazide has an important role in the peroxidation activity of MPO. It is also used in enzyme preparations and in cell cultures.

Uses

4-Aminobenzoic hydrazide can be used as a reactant to synthesize:

Acylhydrazone Schiff base ligand by condensation reaction with 2-acetylpyridine.
Oligomeric transition metal complexes applicable in the fabrication of organic-inorganic hybrid devices with efficient electrical and photoelectrical properties.
Oxovanadium(IV)-hydrazide complex as a potential radical scavenger.

4-Aminobenzohydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Aminobenzohydrazide manufacturers

Career Henan Chemical Co

Product: 4-Aminobenzohydrazide 5351-17-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-07-02

5351-17-7, 4-AminobenzohydrazideRelated Search:

Carbohydrazide Formylhydrazine Phthalhydrazide 1,5-Diphenylcarbazide Tebufenozide Adipic dihydrazide p-Aminobenzamide 1,2-Diformylhydrazine Daminozide Benzoyl hydrazine P-AMINOBENZAMIDE GLUTAMIC ACID 4-Hydroxybenzhydrazide Anthranilamide 4-Aminobenzoic acid METHOXYFENOZIDE Maleic hydrazide antioxidant 1024 4-DIMETHYLAMINOBENZHYDRAZIDE

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4-Aminobenzhydrazide, 98+%

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WLN: ZNUYQR DZ

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Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem

ambenhydrazide

aminostimil

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p-Amino benzoyl hydrazine

p-Aminobenzoic hydrazide

p-amino-benzoicacihydrazide

p-aminobenzoylhydrazine

para-Aminobenzhydrazide

LABOTEST-BB LT00010042

MYELOPEROXIDASE INHIBITOR-I

P-AMINOBENZOIC ACID HYDRAZIDE

P-AMINOBENZHYDRAZIDE

P-AMINOBENZOHYDRAZIDE

P-AMINOBENZOYL HYDRAZIDE

TIMTEC-BB SBB007555

4-AMINOBENZOIC HYDRAZIDE

4-AMINO-BENZOIC ACID HYDRAZIDE

4-AMINOBENZOYLHYDRAZIDE

4-AMINOBENZHYDRAZIDE

4-AMINOBENZOHYDRAZIDE

Myeloperoxidase Inhibitor

4-Aminobenzohydrazide &gt

4-POBN

5351-17-7

H2NC6H4CONHNH2

C7H9ON3

Building Blocks

Carbonyl Compounds

Organic Building Blocks

Hydrazides

Carbonyl Compounds

Hydrazides

Organic Building Blocks

Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes

Amines