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4-Aminobenzohydrazide

Product Name
4-Aminobenzohydrazide
CAS No.
5351-17-7
Chemical Name
4-Aminobenzohydrazide
Synonyms
4-POBN;4NPhCON2;aminostimil;WLN: ZNUYQR DZ;ambenhydrazide;Amben hydrazide;TIMTEC-BB SBB007555;N,4-Diaminobenzamide;P-AMINOBENZHYDRAZIDE;4-AMINOBENZHYDRAZIDE
CBNumber
CB8434256
Molecular Formula
C7H9N3O
Formula Weight
151.17
MOL File
5351-17-7.mol
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4-Aminobenzohydrazide Property

Melting point:
225-227 °C (lit.)
Boiling point:
273.17°C (rough estimate)
Density 
1.2100 (rough estimate)
refractive index 
1.5860 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMF: 10 mg/ml; DMSO: 14 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
pka
13.05±0.10(Predicted)
form 
Crystals or Powder
color 
White or beige
Water Solubility 
Soluble in DMSO (10 mg/ml), dilute acids, and water (partly miscible).
BRN 
639053
CAS DataBase Reference
5351-17-7(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 4-amino-, hydrazide(5351-17-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
DG2580000
HazardClass 
IRRITANT
HS Code 
29280000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A41909
Product name
4-Aminobenzoic hydrazide
Purity
95%
Packaging
10g
Price
$54.6
Updated
2024/03/01
Sigma-Aldrich
Product number
475944
Product name
Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem
Packaging
1g
Price
$96.7
Updated
2024/03/01
TCI Chemical
Product number
A1211
Product name
4-Aminobenzohydrazide
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$131
Updated
2024/03/01
Alfa Aesar
Product number
A10963
Product name
4-Aminobenzhydrazide, 98%
Packaging
100g
Price
$160
Updated
2021/12/16
Alfa Aesar
Product number
A10963
Product name
4-Aminobenzhydrazide, 98%
Packaging
25g
Price
$53.9
Updated
2021/12/16
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4-Aminobenzohydrazide Chemical Properties,Usage,Production

Description

4-Aminobenzoic acid hydrazide (4-ABAH) is an irreversible inhibitor of myeloperoxidase (MPO; IC50 = 0.3 μM). It reduces the production of hypochlorous acid (HOCl) induced by opsonized zymosan or phorbol 12-myristate 13-acetate (PMA; ) in isolated human neutrophils with IC50 values of 16 and 2.2 μM, respectively. 4-ABAH inhibits PMA-induced formation of neutrophil extracellular traps (NETs) in the same cells. It reduces infarct volume and the severity of neurological deficits, as well as increases survival, in a mouse model of cerebral ischemia induced by transient middle cerebral artery occlusion (MCAO) when administered at a dose of 40 mg/kg twice per day.

Chemical Properties

White or beige crystals or powder

Uses

4-Aminobenzhydrazide has an important role in the peroxidation activity of MPO. It is also used in enzyme preparations and in cell cultures.

Uses

4-Aminobenzoic hydrazide can be used as a reactant to synthesize:

  • Acylhydrazone Schiff base ligand by condensation reaction with 2-acetylpyridine.
  • Oligomeric transition metal complexes applicable in the fabrication of organic-inorganic hybrid devices with efficient electrical and photoelectrical properties.
  • Oxovanadium(IV)-hydrazide complex as a potential radical scavenger.

4-Aminobenzohydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Aminobenzohydrazide Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
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View Lastest Price from 4-Aminobenzohydrazide manufacturers

Career Henan Chemical Co
Product
4-Aminobenzohydrazide 5351-17-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-07-02

5351-17-7, 4-AminobenzohydrazideRelated Search:


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