ChemicalBook > CAS DataBase List > 2-BROMOACETAMIDE

2-BROMOACETAMIDE

Product Name
2-BROMOACETAMIDE
CAS No.
683-57-8
Chemical Name
2-BROMOACETAMIDE
Synonyms
BROMOACETAMIDE;2-BroMoacetMide;2-BROMOACETAMIDE;2-bromo-acetamid;Acetamide, 2-bromo-;2-Bromoacetamide98%;2-Bromoacetamide,97%;2-Bromoacetamide >2-BROMOACETAMIDE pure;2-BroMoacetaMide, 98% 5GR
CBNumber
CB8472557
Molecular Formula
C2H4BrNO
Formula Weight
137.96
MOL File
683-57-8.mol
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2-BROMOACETAMIDE Property

Melting point:
87-91 °C(lit.)
Boiling point:
271.6±23.0 °C(Predicted)
Density 
1.4243 (rough estimate)
refractive index 
1.4740 (estimate)
storage temp. 
Inert atmosphere,2-8°C
solubility 
160g/l
pka
14.79±0.40(Predicted)
form 
Crystalline Powder
color 
White
BRN 
1739073
InChI
InChI=1S/C2H4BrNO/c3-1-2(4)5/h1H2,(H2,4,5)
InChIKey
JUIKUQOUMZUFQT-UHFFFAOYSA-N
SMILES
C(N)(=O)CBr
CAS DataBase Reference
683-57-8(CAS DataBase Reference)
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Safety

Hazard Codes 
T,C
Risk Statements 
25-34-20/21/22
Safety Statements 
26-27-36/37/39-45
RIDADR 
UN 2923 8/PG 2
WGK Germany 
3
RTECS 
AB4587000
10
Hazard Note 
Irritant
HazardClass 
8
PackingGroup 
III
HS Code 
29241990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
301272
Product name
2-Bromoacetamide
Purity
98%
Packaging
5g
Price
$64.8
Updated
2025/07/31
Sigma-Aldrich
Product number
301272
Product name
2-Bromoacetamide
Purity
98%
Packaging
25g
Price
$193.2
Updated
2025/07/31
TCI Chemical
Product number
B2852
Product name
2-Bromoacetamide
Purity
>98.0%(GC)(N)
Packaging
5g
Price
$34
Updated
2025/07/31
TCI Chemical
Product number
B2852
Product name
2-Bromoacetamide
Purity
>98.0%(GC)(N)
Packaging
25g
Price
$133
Updated
2025/07/31
TRC
Product number
B679063
Product name
2-Bromoacetamide
Packaging
10g
Price
$75
Updated
2021/12/16
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2-BROMOACETAMIDE Chemical Properties,Usage,Production

Chemical Properties

Very faintly beige fine crystals

Uses

2-Bromoacetamide was used in preparation of (2-carbamoylmethoxy-5-chloro-benzyl)-carbamic acid tert-butyl ester. It was aslo used as precursor to dehydropeptidase I inactivator.

General Description

Kinetics of reaction of 2-bromoacetamide with a 39 base pair duplex DNA sequence was studied.

Hazard

A poison by ingestion. Moderately toxic by skin contact. A severe skin and eye irritant.

Synthesis

22118-09-8

683-57-8

Step 1: To a dichloromethane solution containing the amine (300 mg, 0.71 mmol) and potassium carbonate (290 mg, 2.1 mmol) obtained from Step 1 of Example 51 was slowly added bromoacetyl chloride (71 μL, 0.85 mmol) at room temperature. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the reaction mixture was washed with 0.1 N NaOH aqueous solution and subsequently dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the residue was purified by silica gel column chromatography (eluent: dichloromethane/ethyl acetate, 9:1, v/v) to afford the target product 2-bromoacetamide 281 mg in 73% yield.

References

[1] Journal of the American Chemical Society, 1939, vol. 61, p. 3386
[2] Patent: US2003/216380, 2003, A1

2-BROMOACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-BROMOACETAMIDE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-BROMOACETAMIDE 683-57-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-06
Henan Aochuang Chemical Co.,Ltd.
Product
2-BROMOACETAMIDE 683-57-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-12
Shaanxi Dideu New Materials Co. Ltd
Product
2-BROMOACETAMIDE 683-57-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-19

683-57-8, 2-BROMOACETAMIDERelated Search:


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