ChemicalBook > CAS DataBase List > Indocyanine green

Indocyanine green

Product Name
Indocyanine green
CAS No.
3599-32-4
Chemical Name
Indocyanine green
Synonyms
ICG;Indocyanine;IR-125;nk1611;SO 270;NK 2611;NK 2612;FOXGREEN;IC GREEN;UJOVIRIDIN
CBNumber
CB8478418
Molecular Formula
C43H49N2NaO6S2
Formula Weight
776.98
MOL File
3599-32-4.mol
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Indocyanine green Property

Melting point:
235 °C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
H2O: soluble1mg/mL
form 
Powder
color 
Green-bronze
Appearance
Dark green solid
Water Solubility 
slightly soluble
ex/em
786/820nm (Methanol)
Φ(quantum yield)
0.09
ε(extinction coefficient)
≥115 at 386-396nm in water
≥2000 at 774-784nm in water
≥900 at 712-722nm in water
Merck 
14,4962
BRN 
4115884
InChIKey
JDDBTPDPBRYGPQ-UHFFFAOYSA-N
SMILES
CC1(C(=[N+](CCCCS([O-])(=O)=O)C2C=CC3=CC=CC=C3C1=2)C=CC=CC=CC=C1C(C2C3=CC=CC=C3C=CC=2N1CCCCS(O)(=O)=O)(C)C)C.[NaH]
LogP
-0.290
CAS DataBase Reference
3599-32-4(CAS DataBase Reference)
EPA Substance Registry System
1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt (3599-32-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
DE3150000
HS Code 
32129000
Hazardous Substances Data
3599-32-4(Hazardous Substances Data)
Toxicity
LD50 intravenous in mouse: 60mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
21980
Product name
Cardiogreen
Purity
for microscopy
Packaging
100mg
Price
$230
Updated
2025/07/31
Sigma-Aldrich
Product number
21980
Product name
Cardiogreen
Purity
for microscopy
Packaging
500mg
Price
$907
Updated
2025/07/31
Sigma-Aldrich
Product number
1340009
Product name
Indocyanine green
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
100mg
Price
$463
Updated
2025/07/31
Sigma-Aldrich
Product number
1340009
Product name
Indocyanine green
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
250mg
Price
$434
Updated
2022/05/15
TCI Chemical
Product number
I0535
Product name
Indocyanine Green
Packaging
100mg
Price
$152
Updated
2025/07/31
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Indocyanine green Chemical Properties,Usage,Production

Description

Indocyanine Green (aka ICG, IC Green, Foxgreen) is used for reliable imaging and flow cytometry. This dye is water-soluble and pH-insensitive. The fluorescence of Indocyanine Green is not visible to the human eye but is readily detected by most imaging systems.


Indocyanine Green binds tightly to plasma proteins and becomes confined to the vascular system. The dye has a half-life of 150 to 180 sec and is removed from circulation exclusively by the liver to bile juice.


Indocyanine Green is used for detection of hepatocyte-like cells, determining cardiac output, hepatic function, liver and gastric blood flow, and for ophthalmic angiography.

Chemical Properties

green to brown crystals or crystalline powder

Uses

In infrared photography; in preparation of Wratten filters.

Uses

A tricarbocyanine type of dye with infrared absorbing properties. Diagnostic aid (blood volume determination, cardiac output, hepatic function). Dyes and metabolites.

brand name

IC-Green (Akorn).

Safety Profile

Poison by intravenous route. When heated to decomposition it emits very toxic fumes of SOx, Na2O, and NOx.

storage

Store at -20°C

Abs/Em Maxima

787/819 nm

Fluoresene quantum yield

0.09

Extinction Coefficient

232000

Indocyanine green Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Indocyanine green manufacturers

Changsha YuTeng New Materials Co., Ltd.
Product
Indocyanine green 3599-32-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100kg/M
Release date
2025-07-31
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Indocyanine Green 3599-32-4
Price
US $1.00/g
Min. Order
1g
Purity
95.0% ~ 105.0%
Supply Ability
10KG/month
Release date
2021-06-16
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Indocyanine green 3599-32-4
Price
US $60.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-11-25

3599-32-4, Indocyanine greenRelated Search:

1,1,2-Trimethyl-1H-benz[e]indole Indole-3-carboxylic acid 1,1,2-TRIMETHYL-3-(4-SULFOBUTYL)-1H-BENZ[E]INDOLIUM HYDROXIDE, INNER SALT Indole-5-carboxylic acid Methyl indole-5-carboxylate Indole-4-carboxylic acid 3-Indolepropionic acid 3-Indoleacetonitrile Methyl 1H-indole-7-carboxylate Indole-6-carboxaldehyde Methyl indole-2-carboxylate Methyl indole-4-carboxylate 1H-INDOL-3-YLBORONIC ACID Indole-4-boronic acid Methyl indole-6-carboxylate Ethyl indole-2-carboxylate Indole-7-carboxaldehyde 1-Naphthylhydrazine hydrochloride

  • UJOVIRIDIN
  • Foxgreen, IC Green, Indocyanine green
  • Cardiogreen, Foxgreen, IR-125
  • 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt (1:1)
  • 3-dimethyl-1-(4-sulfonatobutyl)benz(e)indolin-2-ylidene)hepta-1
  • 3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium
  • 5-trien-1-yl)-3
  • Sodium 2-(7-(3
  • 1H-Benz[e]indolium,2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-,inner salt, sodium salt
  • 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)benz[e]indolin-2-ylidene]-1,3,5
  • 3,5-heptatrienyl)-1,1-dimethyl-3-(4-sulfobutyl)-ndol-2-ylidene)-hydroxide
  • anhydro-3,3,3’,3’-tetramethyl-1,1’-bis(4-sulfobutyl)-4,5,4’,5’-dibenzoindotric
  • arbocyaninehydroxideinnersaltsodiumsalt
  • -heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-1h-benz[e]indoliumhydroxideinner
  • innersalt,sodiumsalt
  • ndol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide,
  • sodium 2-(7-(3,3-dimethyl-1-(4-sulfonatobutyl)benz(e)indolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium
  • INDOCYANINE GREEN, USP
  • IR-125, laser grade, pure
  • Indocyanine Green *CAS 3599-32-4*
  • Indocyanine
  • nk1611
  • sodiumsalt(8ci)
  • wofaverdin
  • CARDIOGREEN
  • FOXGREEN
  • HWD INDOCYANINE GREEN
  • ICG
  • IC GREEN
  • INDOCYANINE GREEN
  • INDOCYANIN GREEN
  • IR-125
  • BIS-[1-(4-SULFOBUTYL)-3,3-DIMETHYL-4,5-BENZOINDOLINYLIDEN-2]-HEPTAMETHINECYANINE-BETAINE-SODIUM SALT (INDOCYANINEGREEN, CARDIOGREEN)
  • 4,5-BENZOINDOTRICARBOCYANINE
  • 4-(2-[7-[1,1-DIMETHYL-3-(4-SULFO-BUTYL)-1H-BENZO[E]INDOL-2-YL]-HEPTA-2,4,6-TRIENYLIDENE]-1,1-DIMETHYL-BENZO[E]INDOLIUM-3-YL)-BUTANE-1-SULFONIC ACID SODIUM SALT
  • 1H-BENZ[E]INDOLIUM, 2-[7-[1,1-DIMETHYL-3-(4-SULFOBUTYL)BENZ[E]INDOLIN-2-YLIDENE]-1,3,5-HEPTATRIENYL]-1,1-DIMETHYL-3-(4-SULFOBUTYL)-, HYDROXIDE, INNER SALT, SODIUM SALT
  • 1H-BENZ[E]INDOLIUM, 2-[7-[1,3-DIHYDRO-1,1-DIMETHYL-3-(4-SULFOBUTYL)-2H-BENZ[E]INDOL-2-YLIDENE]-1,3,5-HEPTATRIENYL]-1,1-DIMETHYL-3-(4-SULFOBUTYL)-, HYDROXIDE, INNER SALT, SODIUM SALT
  • 1H-BENZ[E]INDOLIUM, 2-[7-[1,3-DIHYDRO-1,1-DIMETHYL-3-(4-SULFOBUTYL)-2H-BENZ[E]INDOL-2-YLIDENE]-1,3,5-HEPTATRIENYL]-1,1-DIMETHYL-3-(4-SULFOBUTYL)-, INNER SALT, SODIUM SALT
  • NK 2611
  • NK 2612
  • 4-(2-{7-[1,1-Dimethyl-3-(4-sulfo-butyl)-1H-benzo[e]indol-2-yl]-hepta-2,4,6-trienylidene}-1,1-dimethyl-benzo[e]indolium-3-yl)-butane-1-sulfonic acid sodium salt
  • IR-125,pure,laser grade
  • Cardiogreen,Foxgreen, IC Green, Indocyanine green
  • Indocyanine Green (~90%)
  • Indocyanine Green (250 mg)
  • 4-(2-{7-[1,1-Dimethyl-3-(4-sulfo-butyl)-1H-benzo[e]indol-2-yl]-hepta-2,4,6-trienylidene}-1,1-dimethyl-benzo[e]indolium-3-yl)-butane-1-sulfonic acid sodium
  • sodiuM 2-[(1E,3E,5E)-7-[(2Z)-1,1-diMethyl-3-(4-sulfonatobutyl)-1H,2H,3H-benzo[e]indol-2-ylidene]hepta-1,3,5-trien-1-yl]-3,3-diMethyl-1-(4-sulfonatobutyl)-3H-benzo[f]indol-1-iuM
  • IR-125, laser grade, pure 100MG
  • 2-[7-[1,3-Dihydro-1,1-diMethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-diMethyl-3-(4-sulfobutyl)-1H-benz[e]indoliuM Inner Salt SodiuM Salt
  • Opthagreen
  • SO 270
  • Cardio-green Foxgreen
  • Indocyanine Green, dye content 90%
  • Indocyanine Gree
  • )-1,3,5-heptatrienyl)-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide,innersalt,
  • ,innersalt,sodiumsalt(9ci)
  • -1,3,5-heptatrienyl)-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide,innersalt,so
  • 1h-benz(e)indolium,2-(7-(1,1-dimethyl-3-(4-sulfobutyl)benz(e)indolin-2-ylidene