4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
- Product Name
- 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
- CAS No.
- 2154342-45-5
- Chemical Name
- 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
- Synonyms
- Poma-C3-NH2·HCl;Pomalidomide-C3-NH2 HCl;Pomalidomide-C3-amine HCl;Thalidomide-NH-C4-NH2 HCl;Pomalidomide 4'-alkylC3-amine;Pomalidomide 4'-alkylC3-amine hydrochloride;4-(3-aminopropylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl;4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride;4-[(3-aminopropyl)amino]-2-(2,6-dioxopiperidin-3- yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
- CBNumber
- CB84796316
- Molecular Formula
- C16H19ClN4O4
- Formula Weight
- 366.79946
- MOL File
- 2154342-45-5.mol
4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Property
- storage temp.
- Store at -20°C
- form
- Solid
- color
- Off-white to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H312Harmful in contact with skin
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- AS00952
- Product name
- 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneHCl
- Purity
- 97%
- Packaging
- 1g
- Price
- $660
- Updated
- 2021/12/16
- Product number
- AS00952
- Product name
- 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneHCl
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $1100
- Updated
- 2021/12/16
4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Chemical Properties,Usage,Production
Uses
Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
IC 50
Cereblon
storage
Store at -20°C
References
[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277
4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl manufacturers
- Product
- Pomalidomide-C3-NH2 hydrochloride 2154342-45-5
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >99.00%
- Supply Ability
- 100mg
- Release date
- 2024-04-01