ChemicalBook > CAS DataBase List > 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl

4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl

Product Name
4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
CAS No.
2154342-45-5
Chemical Name
4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
Synonyms
Poma-C3-NH2·HCl;Pomalidomide-C3-NH2 HCl;Pomalidomide-C3-amine HCl;Thalidomide-NH-C4-NH2 HCl;Pomalidomide 4'-alkylC3-amine;Pomalidomide 4'-alkylC3-amine hydrochloride;4-(3-aminopropylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl;4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride;4-[(3-aminopropyl)amino]-2-(2,6-dioxopiperidin-3- yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
CBNumber
CB84796316
Molecular Formula
C16H19ClN4O4
Formula Weight
366.79946
MOL File
2154342-45-5.mol
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4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Property

storage temp. 
Store at -20°C
form 
Solid
color 
Off-white to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H312Harmful in contact with skin

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Acrotein
Product number
AS00952
Product name
4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneHCl
Purity
97%
Packaging
1g
Price
$660
Updated
2021/12/16
Acrotein
Product number
AS00952
Product name
4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneHCl
Purity
97%
Packaging
0.25g
Price
$1100
Updated
2021/12/16
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4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Chemical Properties,Usage,Production

Uses

Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Suppliers

China 41 United States 3 Global 44
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
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View Lastest Price from 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Pomalidomide-C3-NH2 hydrochloride 2154342-45-5
Price
US $0.00/mg
Min. Order
100mg
Purity
>99.00%
Supply Ability
100mg
Release date
2024-04-01

2154342-45-5, 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HClRelated Search:

4-[(4-Aminobutyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Pomalidomide-C6-NH2?hydrochloride 1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 4-((4-azidobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione -alkylC5-amine 6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid Poma-C8-N3

  • 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
  • 4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
  • 4-[(3-aminopropyl)amino]-2-(2,6-dioxopiperidin-3- yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
  • Thalidomide-NH-C4-NH2 HCl
  • Inhibitor,E3 Ligase Ligand-Linker Conjugates,inhibit,Pomalidomide C3 NH2 hydrochloride,Pomalidomide-C-3-NH2 hydrochloride,PomalidomideC3NH2 hydrochloride
  • Pomalidomide 4'-alkylC3-amine hydrochloride
  • Poma-C3-NH2·HCl
  • Pomalidomide-C3-amine HCl
  • 4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride , Pomalidomide-C3-NH2 HCl
  • 4-(3-aminopropylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
  • Pomalidomide 4'-alkylC3-amine
  • Pomalidomide-C3-NH2 HCl
  • 2154342-45-5