4-Hydroxy-2-butanone

Product Name: 4-Hydroxy-2-butanone
CAS No.: 590-90-9
Chemical Name: 4-Hydroxy-2-butanone
Synonyms: 4-hydroxybutan-2-one;CH3C(O)CH2CH2OH;Methylolacetone;2-Butanone, 4-hydroxy-;3-Oxobutanol;Butanone glycol;3-Ketobutan-1-ol;H**4-HYDROXY-2-BUTANONE;ketobutanol;3-Oxo-1-butanol
CBNumber: CB8493505
Molecular Formula: C4H8O2
Formula Weight: 88.11
MOL File: 590-90-9.mol

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4-Hydroxy-2-butanone Property

Melting point:: 15°C (estimate)
Boiling point:: 73-76 °C/12 mmHg (lit.)
Density: 1.023 g/mL at 25 °C (lit.)
refractive index: 1.430
Flash point:: 91°F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform, Methanol (Slightly)
form: Oil
pka: 14.43±0.10(Predicted)
color: Clear Colourless
Water Solubility: Miscible with water, alcohol, ethanol and ether.
BRN: 1737666
LogP: -1.209 at 25℃
CAS DataBase Reference: 590-90-9(CAS DataBase Reference)
NIST Chemistry Reference: 4-Hydroxy-2-butanone(590-90-9)
EPA Substance Registry System: 2-Butanone, 4-hydroxy- (590-90-9)

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Safety

Risk Statements: 10
Safety Statements: 16-24/25
RIDADR: UN 1993
WGK Germany: 3
TSCA: Yes
HazardClass: 3
HS Code: 29144000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 252557
Product name: 4-Hydroxy-2-butanone
Purity: 95%
Packaging: 100g
Price: $181
Updated: 2025/07/31

TCI Chemical

Product number: H0584
Product name: 4-Hydroxy-2-butanone
Purity: >95.0%(GC)
Packaging: 25mL
Price: $38
Updated: 2025/07/31

TCI Chemical

Product number: H0584
Product name: 4-Hydroxy-2-butanone
Purity: >95.0%(GC)
Packaging: 100mL
Price: $111
Updated: 2025/07/31

TCI Chemical

Product number: H0584
Product name: 4-Hydroxy-2-butanone
Purity: >95.0%(GC)
Packaging: 500mL
Price: $392
Updated: 2025/07/31

TRC

Product number: H819000
Product name: 4-Hydroxy-2-butanone
Packaging: 25g
Price: $165
Updated: 2021/12/16

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4-Hydroxy-2-butanone Chemical Properties,Usage,Production

Chemical Properties

Colourless to pale yellow liquid

Uses

4-Hydroxy-2-butanone is used in the preparation of fused benzazepine molecules as selective D3 receptor antagonists with pharmaceutical activity. It is also used in the preparation of verrucarin and mevalonic acid lactone. Further, it is used to prepare 3-buten-2-one through dehydration over an anatase titanium dioxide catalyst. It is also employed in the preparation of 4-methyl-5-hydroxymethylthiazole, (±)-lineatin and beta-hydroxylactones.

Application

4-Hydroxy-2-butanone has been used in the synthesis of:

3-buten-2-one via dehydration over anatase-TiO2 catalyst
4-methyl-5-hydroxymethylthiazole
(±)-lineatin
mevalonic acid lactone
verrucarin
β-hydroxylactones

Definition

ChEBI: A beta-hydroxy ketone that is butan-2-one substituted by a hydroxy group at position 4.

General Description

4-Hydroxy-2-butanone is an important pharmaceutical intermediate. Gas phase reaction of the OH radicals with 4-hydroxy-2-butanone has been investigated by absolute rate method.

4-Hydroxy-2-butanone Preparation Products And Raw materials

Raw materials

Acetone Vitamin A Formaldehyde Potassium carbonate Paraformaldehyde Hydrochloric acid Methyl vinyl ketone

Preparation Products

Methyl vinyl ketone

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4-Hydroxy-2-butanone Suppliers

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View Lastest Price from 4-Hydroxy-2-butanone manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 4-Hydroxy-2-butanone 590-90-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-05-20

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Hydroxy-2-butanone 590-90-9
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-25

Hebei Yanxi Chemical Co., Ltd.

Product: 4-Hydroxy-2-butanone 590-90-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 95%+
Supply Ability: 30MT/Month
Release date: 2023-01-30

590-90-9, 4-Hydroxy-2-butanoneRelated Search:

Methylparaben Kresoxim-methyl CHLOROPHOSPHONAZO III Bensulfuron methyl 4-Cyanophenol 2-Butanone oxime Methyl acrylate 2-(METHYLSULFONYL)ETHANOL 4-Methyl-2-pentanone Methyl Parathion-methyl Acetoin 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Methyl 4-chloro-3-oxo-butanoate Ethyl 4,4,4-trifluoroacetoacetate Ethyl 2-oxocyclopentanecarboxylate Ethyl 2-oxocyclohexanecarboxylate Mordant Blue 29

H**4-HYDROXY-2-BUTANONE

2-Butanone, 4-hydroxy-

2-Butanone,4-hydroxy-

3-Ketobutan-1-ol

3-Oxo-1-butanol

3-Oxobutanol

4-Butanol-2-one

4-hydroxy-2-butanon

CH3C(O)CH2CH2OH

Methylolacetone

Monomethylolacetone

4-HYDROXY-2-BUTANONE

2-HYDROXYETHYL METHYL KETONE

4-hydroxybutan-2-one

4-Hydroxy-2-butanone,95%

ketobutanol

1-Hydroxy-3-butanone

Hydroxy-2-butan

4-Hydroxy-2-butanone , 95.0%(GC)

4-hydrxy-2-butone

Butanone glycol

4-Hydroxy-2-butanone &gt

Ethyl Acetate Impurity 195

590-90-9

590-50-9

HOCH2CH2COCH3

KETONE

Organic Building Blocks

Ketones

Carbonyl Compounds

C3 to C6

Building Blocks

in-stock

straight chain compounds

ketone

1

bc0001

590-90-9

john's