NU7026

Product Name: NU7026
CAS No.: 154447-35-5
Chemical Name: NU7026
Synonyms: CS-595;LY 293646;NU7026, >=98%;NU 7026; NU-7026;NU7026 USP/EP/BP;NU7026;LY293646; NU-7026;DNA-PK Inhibitor II NU7026 NU-7026;2-MORPHOLINO-4H-BENZO[H]CHROMEN-4-ONE;2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one;2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one
CBNumber: CB8503981
Molecular Formula: C17H15NO3
Formula Weight: 281.31
MOL File: 154447-35-5.mol

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NU7026 Property

Melting point:: 267-269 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling point:: 459.9±45.0 °C(Predicted)
Density: 1.330
storage temp.: 2-8°C
solubility: DMSO: 3 mg/mL at 60 °C, soluble
form: solid
pka: 0.49±0.20(Predicted)
color: tan

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N1537
Product name: NU7026
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $279
Updated: 2024/03/01

Sigma-Aldrich

Product number: 260961
Product name: DNA-PK Inhibitor II
Packaging: 5mg
Price: $245
Updated: 2024/03/01

Cayman Chemical

Product number: 13308
Product name: NU 7026
Purity: ≥95%
Packaging: 5mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 13308
Product name: NU 7026
Purity: ≥95%
Packaging: 10mg
Price: $152
Updated: 2024/03/01

Cayman Chemical

Product number: 13308
Product name: NU 7026
Purity: ≥95%
Packaging: 25mg
Price: $356
Updated: 2024/03/01

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NU7026 Chemical Properties,Usage,Production

Uses

DNA-PK Inhibitor II is an antiproliferative agent, and inhibitor of DNA-PK.

Uses

NU7026 has been used:

as a DNA-dependent protein kinase (DNA-PK) inhibitor, to pre-treat colon cancer cell
in kinase inhibitor experiments for treating zygotes with visible pronuclei post 20 h-human chorionic gonadotropin (hCG)
to determine its influence on cytotoxicity of dibenzo[def,p]chrysene on HepG2 cells

Definition

ChEBI: 2-(4-morpholinyl)-4-benzo[h][1]benzopyranone is an organooxygen compound and an organic heterotricyclic compound.

Biological Activity

ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK). Displays selectivity over other PIKK family enzymes (IC 50 values are 0.23, 13.0, > 100 and > 100 μ M for DNA-PK, PI3K, ATM and ATR respectively). Radiosensitizes both proliferating and quiescent mouse embryonic fibroblast cells to IR and inhibits DSB repair.

Biochem/physiol Actions

Cell permeable, small molecule benzochromenone inhibitor of DNA-PK (DNA dependent protein kinase).

storage

Store at +4°C

NU7026 Preparation Products And Raw materials

Raw materials

Preparation Products

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NU7026 Suppliers

China 86 India 1 Switzerland 1 United Kingdom 2 United States 14 Global 104

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32063
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

ApexBio Technology

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Country: United States
ProdList: 6251
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Cayman Chemical Company

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Country: United States
ProdList: 6213
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Creative Enzymes

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Country: United States
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Combi-Blocks Inc.

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Country: United States
ProdList: 6618
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Riedel-de Haen AG

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ProdList: 6773
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Matrix Scientific

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Country: United States
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Exlcusive Chemistry Ltd

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Santa Cruz Biotechnology, Inc.

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Email: scbt@scbt.com
Country: United States
ProdList: 3597
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View Lastest Price from NU7026 manufacturers

Career Henan Chemical Co

Product: NU7026 154447-35-5
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2019-12-24

154447-35-5, NU7026Related Search:

Imidazolidinyl urea NU7441 (KU-57788) KU-55933 (ATM Kinase Inhibitor) VE-821 KU-60019 ABT 737 Olaparib NU7026 4H-1-Benzopyran-4-one, 2-(diethylamino)-

DNA-PK Inhibitor II - CAS 154447-35-5 - Calbiochem

NU 7026; NU-7026

CS-595

2-MORPHOLINO-4H-BENZO[H]CHROMEN-4-ONE

NU7026, >=98%

2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one

NU7026;LY293646; NU-7026

LY 293646

2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one

4H-Naphtho[1,2-b]pyran-4-one, 2-(4-morpholinyl)-

2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one NU7026

NU7026 USP/EP/BP

DNA-PK Inhibitor II NU7026 NU-7026

DNA-dependent protein kinase,inhibit,NU-7026,Apoptosis,DNA-PK,LY-293646,Inhibitor,LY 293646,NU 7026

154447-35-5

Inhibitors