2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

Uses Reactions

Product Name: 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
CAS No.: 657408-07-6
Chemical Name: 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
Synonyms: 98% SPhos;Dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphane;dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphane;6´NS-PHOS;SPhos 97%;SPhos, >=98%;REF DUPL: S-PHOS;-diMethoxybiphenyl;S-Phos, ChemDose(TM) tablets
CBNumber: CB8634850
Molecular Formula: C26H35O2P
Formula Weight: 410.53
MOL File: 657408-07-6.mol

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2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl Property

Melting point:: 164-166°C
Boiling point:: 513.3±40.0 °C(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: soluble in Chloroform
form: crystal
color: white
Sensitive: Air Sensitive
InChIKey: VNFWTIYUKDMAOP-UHFFFAOYSA-N

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Safety

Hazard Codes: Xn
Risk Statements: 40
Safety Statements: 24/25-36/37
WGK Germany: 3
TSCA: No
HS Code: 2931499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H351Suspected of causing cancer
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 901906
Product name: SPhos
Purity: 95%
Packaging: 1G
Price: $31.44
Updated: 2024/03/01

Sigma-Aldrich

Product number: 901906
Product name: SPhos
Purity: 95%
Packaging: 5G
Price: $143
Updated: 2024/03/01

Sigma-Aldrich

Product number: 901906
Product name: SPhos
Purity: 95%
Packaging: 25G
Price: $270.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 932191
Product name: SPhos ChemBeads
Packaging: 1g
Price: $287
Updated: 2024/03/01

Sigma-Aldrich

Product number: 901906
Product name: SPhos
Purity: 95%
Packaging: 250G
Price: $736
Updated: 2024/03/01

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2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl Chemical Properties,Usage,Production

Uses

SPhos [2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.
SPhos may be used as a ligand in the following processes:
• Palladium catalyzed Suzuki-Miyaura cross-coupling reaction between Boc-protected aminomethyltrifluoroborate and aryl chlorides or hetaryl chlorides to form the corresponding aminomethylarenes.• Palladium catalyzed Suzuki-Miyaura cross-coupling reaction between 4-methyl-substituted piperidinylzinc reagent and different aryl or heteroaryl iodides to form various substituted piperidines.• Intramolecular Suzuki-Miyaura coupling to form the 18-membered macrocyclic ring during the multi-step synthesis of riccardin C.
Utilized in conjunction with palladium to form a highly active catalyst for C-N bond formation.
Highly universal ligand for Suzuki-Miyaura coupling; aryl chlorides, hindered biaryls, heterobiaryls.

Reactions

Ligand/palladium catalyst for general Suzuki-Miyaura cross-coupling reactions.
Ligand/palladium catalyst for the Suzuki-Miyaura coupling of aryltrifluoroborates with aryl chlorides.
Ligand/palladium catalyst for the Suzuki-Miyaura reaction of heteroaryl halides and heteroaryl boronic acids and esters.
Ligand/palladium catalyst for the Kumada-Corriu cross-coupling reaction.
Ligand/palladium catalyst for the borylation of aryl halides with pinacol borane.
Suzuki couplings involving amino acids. Synthesis of biaryl derivatives of 4-hydroxyphenyl glycine, tyrosine and tryptophan.
Synthesis of substituted adamantylzinc reagents using Mg-insertion in the presence of zinc chloride.
Highly efficient catalyst for the palladium-catalyzed Suzuki-Miyura reaction of heteroaryl halides and heteroaryl boronic acids
and esters.

Chemical Properties

White solid

Uses

S-Phos is a catalyst that is used in the preparation of thiadiazoles as DGAT1 inhibitors with potential in metabolic diseases treatment.

Uses

suzuki reaction

General Description

SPhos [2-Dicyclohexylphosphino-2′, 6′-dimethoxybiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl Preparation Products And Raw materials

Raw materials

Dicyclohexylchlorophosphine 1,3-Dimethoxybenzene Tetrahydrofuran 1,2-Dibromobenzene Ethyl acetate PETROLEUM ETHER Magnesium n-Butyllithium

Preparation Products

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2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl Suppliers

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View Lastest Price from 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl manufacturers

Jinan Finer Chemical Co., Ltd

Product: 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl 657408-07-6
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%
Supply Ability: 200mt
Release date: 2022-01-25

XINXIANG RUNYU MATERIAL CO., LTD.

Product: 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl 657408-07-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 500kg
Release date: 2021-11-23

Hebei Guanlang Biotechnology Co,.LTD

Product: SPHOS 657408-07-6
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2023-06-09

657408-07-6, 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenylRelated Search:

X-PHOS 2-(Dicyclohexylphosphino)-2'-methylbiphenyl 2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl Diphenyldimethoxysilane Dimethyldimethoxysilane trans-Bifenthtin Bifendate 1,1-Dimethoxyethane 2-(Dicyclohexylphosphino)biphenyl 2-DICYCLOHEXYLPHOSPHINO-2',6'-DIISOPROPOXYBIPHENYL DI-N-PENTYLPHENYLPHOSPHINE 2-(DICYCLOHEXYLPHOSPHINO)-2'-HYDROXYBIPHENYL DICYCLOHEXYLPHOSPHINE CYCLOHEXYLPHOSPHINE Dicyclohexylphenylphosphine 2'-DICYCLOHEXYLPHOSPHINO-2,6-DIMETHOXY-3-SULFONATO-1,1'-BIPHENYL HYDRATE SODIUM SALT 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

98% SPhos

2-Dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl ,98%

2-Dicyclohexylphosphino-2', 6-diMethoxybihenyl

2-DicyclohexylphosphiNA-2',6'-diMethoxybiphenyl

Dicyclohexyl(2',6'-diMethoxy-[1,1'-biphenyl]-2-yl)phosphine

SPhos 97%

2-Dicyclohexylphosphino-2',6'-diMethoxybiphenyl, 6'-diMethoxybiphenyl

2 - dicyclohexyl phosphine - 2 ', 6 '- diMethoxy - 1, 1' - two PCB

2-Dicyclohexylphosphino-2',6'-

2-Dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl,98% Sphos

2-(Dicyclohexylphosphanyl)-2',6'-dimethoxybiphenyl

S-Phos, ChemDose? tablets

dicyclohexyl({2-[(2,6-dimethoxyphenyl)methyl]phenyl}methyl)phosphane

2-Dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl, min. 98%

Dicyclohexyl(2',6'-diMethoxy-[1,1'-biphenyl

S-phos, 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl Sphos

Sphos / 2-Dicyclohexylphosphino-2'',6''-dimethoxy-1,1''-biphenyl

2-(Dicyclohexylphosphanyl)-2',6'-dimethoxybiphenyl 98%

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl 657408-07-6 250g

-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

2-DICYLOHEXYLPHOSPHINO-2,6-DIMETHOXYBIPHENYL

Phosphine,dicyclohexyl(2',6'-dimethoxy[1,1'-biphenyl]-2-yl)-

SPhos, >=98%

2-Dicyclohexylphosphino-2’,6’-dimethoxy-1,1’-biphenyl (S-Phos)

2-DICYCLOHEXYLPHOSPHINO-2',6'-DIMETHOXY-1,1'-BIPHENYL, MIN. 98% S-PHOS

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl, min. 98%

S-Phos impregnated tablets, ChemDose(R), S-Phos tablets, 2-Dicyclohexylphosphino-2μ,6μ-dimethoxybiphenyl impregnated tablets

S-Phos, ChemDose(R) tablets

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

6&acute

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl, 98+%

REF DUPL: S-PHOS

Dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphane

2-Dicyclohexylphosphino-2',6'-dimethoxybipheny

Dicyclohexyl(2',6'-dimethoxybiphenyl-2-yl)phosphine

2-Dicyclohexylphosphino-2&acute

-diMethoxybiphenyl

S-PHOS, 2-Dicyclohexylphosphino-2,6-di-Methyloxy-1,1-biphenyl

phosphino-2’,6’-dimethoxybiphenyL

phosphino-2',6'-dimethoxy-1,1'-biphenyL

NS-PHOS

S-Phos, ChemDose(TM) tablets

2-Dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl,min.98%

2-Dicyclohexyphosphino-2'6'-dimethoxy-1,1'-biphenyl (Sphos)

dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphane

S-Phos (2-Dicyclohexylphosphino-2,6-Dimethoxybiphenyl) extrapure, 98%

Dicyclohexyl(2',6'-dimethoxybiphenyl-2-yl)phosphine(S-PHOS)

2-DICYCLOHEXYLPHOSPHINO-2',6'-DIMETHOXY-1,1'-BIPHENYL

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl(Sphos)

Dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine

dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphane

657408-07-6

C26H35O2P

C28H39O2P

Phosphines

Achiral Phosphine