2'-Deoxy-2'-fluorocytidine
- Product Name
- 2'-Deoxy-2'-fluorocytidine
- CAS No.
- 10212-20-1
- Chemical Name
- 2'-Deoxy-2'-fluorocytidine
- Synonyms
- 2'-FC;2'-FdC;RO-8013;2'-F-dC;2'-FANA-C;NSC 529432;2’-F-2’-dC;2'-FLUORO-D-CYTIDINE;2'-F-2'-deoxyCytidine;2'-F-2'-deoxycytidine
- CBNumber
- CB8670324
- Molecular Formula
- C9H12FN3O4
- Formula Weight
- 245.21
- MOL File
- 10212-20-1.mol
2'-Deoxy-2'-fluorocytidine Property
- Melting point:
- 167 °C
- Boiling point:
- 500.1±60.0 °C(Predicted)
- Density
- 1.82±0.1 g/cm3(Predicted)
- refractive index
- 80 ° (C=1, MeOH)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- Soluble in DMSO, Methanol.
- pka
- 12.84±0.70(Predicted)
- form
- Powder
- color
- White to Off-white
- Water Solubility
- Water: 5 mg/mL (20.39 mM; ultrasonic and warming and heat to 60°C)
- InChI
- InChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6-,7-,8-/m1/s1
- InChIKey
- NVZFZMCNALTPBY-XVFCMESISA-N
- SMILES
- OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](F)[C@@H]1O
- CAS DataBase Reference
- 10212-20-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- D3614
- Product name
- 2'-Deoxy-2'-fluorocytidine Hydrate
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $68
- Updated
- 2024/03/01
- Product number
- J65632
- Product name
- 2'-Fluoro-2'-deoxycytidine, 99%
- Packaging
- 1g
- Price
- $52.65
- Updated
- 2024/03/01
- Product number
- D232945
- Product name
- 2’-Deoxy-2’-fluoroCytidine
- Packaging
- 2g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- D232945
- Product name
- 2’-Deoxy-2’-fluoroCytidine
- Packaging
- 10g
- Price
- $525
- Updated
- 2021/12/16
- Product number
- 33485
- Product name
- 2?-Deoxy-2?-fluorocytidine
- Purity
- 98%purewithdatedHPLCUVchromatogram
- Packaging
- 1mg
- Price
- $685
- Updated
- 2021/12/16
2'-Deoxy-2'-fluorocytidine Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine has been shown to inhibit Borna Disease virus replication and s pread.
in vitro
2'-Deoxy-2'-fluorocytidine has antiviral activities, showing 50% effective concentrations (EC50) of 61 nM and 31 nM against CCHFV and CCHFV/ZsG in Huh7 cells, respectively. And it shows a 50% cytotoxicity concentration (CC50) of >50.0 μM in Huh7 cells.
References
[1] Stephen R. Welch. “Identification of 2′-deoxy-2′-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus.” Antiviral research 147 (2017): Pages 91-99.
2'-Deoxy-2'-fluorocytidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2'-Deoxy-2'-fluorocytidine manufacturers
- Product
- 2'-Deoxy-2'-fluorocytidine 10212-20-1
- Price
- US $0.00/g
- Min. Order
- 100g
- Purity
- ≥98%
- Supply Ability
- 20t
- Release date
- 2023-05-11
- Product
- 2'-FLUORO-D-CYTIDINE 10212-20-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 500kg per month
- Release date
- 2022-12-27
- Product
- 2'-F-2'-deoxyCytidine;2‘-F-dC 10212-20-1
- Price
- US $100.00/kg
- Min. Order
- 0.009999999776482582kg
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2023-03-21