5-Nitrobenzimidazole
- Product Name
- 5-Nitrobenzimidazole
- CAS No.
- 94-52-0
- Chemical Name
- 5-Nitrobenzimidazole
- Synonyms
- nci-c01912;BIO-FARMA BF002407;6-nitrobenzimdazole;6-nitro-benzimidazo;5-Nrtiobenzimidazole;6-NITROBENZIMIDAZOLE;5-nitro-benzimidazol;6-nitro-benzimidazol;5-NITROBENZIMIDAZOLE;5-Nitrobenzimidizole
- CBNumber
- CB8697293
- Molecular Formula
- C7H5N3O2
- Formula Weight
- 163.13
- MOL File
- 94-52-0.mol
5-Nitrobenzimidazole Property
- Melting point:
- 207-210 °C
- Boiling point:
- 290.19°C (rough estimate)
- Density
- 1.4141 (rough estimate)
- bulk density
- 270kg/m3
- refractive index
- 1.5500 (estimate)
- storage temp.
- Store below +30°C.
- solubility
- 0.5g/l
- pka
- 10.95±0.10(Predicted)
- form
- Solid
- color
- Light Beige
- PH
- 6 (10g/l, H2O, 20℃)(slurry)
- Water Solubility
- <0.01 g/100 mL at 16.5 ºC
- BRN
- 7926
- Henry's Law Constant
- 2.7×101 mol/(m3Pa) at 25℃, HSDB (2015)
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
- InChI
- 1S/C7H5N3O2/c11-10(12)5-1-2-6-7(3-5)9-4-8-6/h1-4H,(H,8,9)
- InChIKey
- XPAZGLFMMUODDK-UHFFFAOYSA-N
- SMILES
- [N+](=O)([O-])c1cc2[nH]cnc2cc1
- CAS DataBase Reference
- 94-52-0(CAS DataBase Reference)
- EPA Substance Registry System
- 5-Nitrobenzimidazole (94-52-0)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-40-22
- Safety Statements
- 26-45-36/37
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- DD9800000
- TSCA
- TSCA listed
- HS Code
- 29339990
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 - Hazardous Substances Data
- 94-52-0(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S763799
- Product name
- 6-NITROBENZIMIDAZOLE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $197
- Updated
- 2026/04/30
- Product number
- 8.18257
- Product name
- 5-Nitrobenzimidazole
- Purity
- for synthesis
- Packaging
- 100g
- Price
- $127
- Updated
- 2026/04/30
- Product number
- S763799
- Product name
- 6-NITROBENZIMIDAZOLE
- Purity
- Aldrich
- Packaging
- 50mg
- Price
- $179
- Updated
- 2024/03/01
- Product number
- N0152
- Product name
- 5-Nitrobenzimidazole
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $143
- Updated
- 2026/04/30
- Product number
- N494795
- Product name
- 5-Nitrobenzimidazole
- Packaging
- 100g
- Price
- $220
- Updated
- 2021/12/16
5-Nitrobenzimidazole Chemical Properties,Usage,Production
Chemical Properties
white or pale yellow powder
Uses
Antifogging agent in photographic developers.
Uses
5-Nitrobenzimidazole acts as a reagent in the synthesis of benzimidazoles derivatives with antibacterial and antifungal activities. It also functions as a reagent in the synthesis of xanthine oxidase, a key enzyme that catalyze xanthine to uric acid causing hyperuricemia in humans.
General Description
Off-white to pale yellow fluffy powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
5-Nitrobenzimidazole is incompatible with strong oxidizing agents and strong bases.
Fire Hazard
Flash point data for 5-Nitrobenzimidazole are not available but 5-Nitrobenzimidazole is probably combustible.
Synthesis
64-18-6
99-56-9
94-52-0
First, 4-nitrophthalimide (1 g) was mixed with formic acid (0.74 mL) in 5N hydrochloric acid (70 mL), stirred and heated to reflux for 24 hours. Upon completion of the reaction, the mixture was cooled to room temperature, neutralized with 10% sodium hydroxide solution and the precipitate was isolated. Subsequently, the precipitate was recrystallized with water and dried to give 5-nitrobenzimidazole (0.69 g) [37].
References
[1] Molecules, 2015, vol. 20, # 8, p. 15206 - 15223
[2] Journal of the Korean Chemical Society, 2010, vol. 54, # 5, p. 589 - 593
[3] Journal of the Chilean Chemical Society, 2012, vol. 57, # 2, p. 1122 - 1125,4
[4] Journal of Medicinal Chemistry, 2015, vol. 58, # 24, p. 9591 - 9600
[5] Journal of the Chemical Society of Pakistan, 2018, vol. 40, # 2, p. 366 - 374
5-Nitrobenzimidazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Nitrobenzimidazole manufacturers
- Product
- 5-Nitrobenzimidazole (6-NitrobenziMidazole) 94-52-0
- Price
- US $0.00/Kg/Bag
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 2000kg/month
- Release date
- 2021-06-04
- Product
- 5-Nitrobenzimidazole 94-52-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-17
- Product
- 5-Nitrobenzimidazole 94-52-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000KG
- Release date
- 2024-08-14