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Tocoretinate

Product Name
Tocoretinate
CAS No.
40516-48-1
Chemical Name
Tocoretinate
Synonyms
N 021;L 300;Olcenon;TOCORETINATE;tretinoin tocoferil;dl-α-Tocopheryl Retinoate;dl-a-Tocopheryl Retinoate;VITAMIN E VITAMIN A ACID ESTER;Retinoic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, (±)-;Retinoic acid, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-(+-)-
CBNumber
CB8700933
Molecular Formula
C49H76O3
Formula Weight
713.13
MOL File
40516-48-1.mol
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Tocoretinate Property

Boiling point:
761.3±60.0 °C(Predicted)
Density 
0.959±0.06 g/cm3(Predicted)
CAS DataBase Reference
40516-48-1(CAS DataBase Reference)
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Safety

Toxicity
LD50 in mice (mg/kg): >1000 i.v.; >2000 orally (Fukawa, 1975)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
T526200
Product name
dl-α-TocopherylRetinoate
Packaging
10mg
Price
$55
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004438
Product name
TOCORETINATE
Purity
95.00%
Packaging
250MG
Price
$730
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004438
Product name
TOCORETINATE
Purity
95.00%
Packaging
500MG
Price
$1020
Updated
2021/12/16
AHH
Product number
API-1775
Product name
Tocoretinate
Purity
98%
Packaging
1g
Price
$910
Updated
2021/12/16
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Tocoretinate Chemical Properties,Usage,Production

Description

Tretinoin tocoferil, the a-tocopherol ester of all-trans-retinoic acid, was launched for the treatment of bedsores and skin ulcers such as burn, leg, and diabetic ulcers. It is also an orally active agent for gastric ulcer treatment. Tretinoin tocoferil represents a new class of antiulcer drugs which act by directly promoting tissue repair, distinguished from common drugs that exert an indirect function by suppression of acid-secretion and mucosa protection. The mode of its action has been proposed to relate to its ability to stimulate DNA synthesis of growth-arrested human skin fibroblasts by promoting expression of the epidermal growth factor receptor.

Originator

Nisshin Flour Milling (Japan)

Uses

dl-α-Tocopheryl Retinoate is an α-tocopherol ester of all-trans retinoic acid (R250200) and is safely used in the treatment of skin ulcer. ?dl-α-Tocopheryl Retinoate inhibited proliferation of human promyelocytic leukemia HL-60 cells and induced granulocytic differentiation of the cells, but to a lesser extent than did retinoic acid.

Definition

ChEBI: Tocoretinate is a tocol.

brand name

Olcenon

Tocoretinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Tocoretinate Suppliers

Wuhan Wei Shunda Technology Development Co., Ltd.
Tel
86-027-88774375
Fax
86-027-88416321
Email
mwmwhot@163.com
Country
China
ProdList
233
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Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
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Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ:800101999
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cdhxsj@163.com
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China
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Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
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025-57018008
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Country
China
ProdList
5800
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Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
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58
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
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sales@xiyashiji.com
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China
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Wellman Pharmaceutical Group Limited
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027-83991220
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027-87466105 15377573527
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Hefei TNJ Chemical Industry Co.,Ltd.
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Dayang Chem (Hangzhou) Co.,Ltd.
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571-88938639 +8617705817739
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SIMAGCHEM CORP
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China
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Hubei Jinsuo Biological Technology Co., Ltd.
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Hubei widely chemical technology Co., Ltd.
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CONIER CHEM AND PHARMA LIMITED
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career henan chemical co
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Wuhan Dingxintong Pharmaceutical Co. , Ltd.
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Shandong Tianming Biotechnology Development Co. Ltd
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GIHI CHEMICALS CO.,LIMITED
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Taizhou Xinridong Biotechnology Co., Ltd
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A.T.CHEMICAL
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Alway Chem, China
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View Lastest Price from Tocoretinate manufacturers

Career Henan Chemical Co
Product
Tocoretinate 40516-48-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-31

40516-48-1, TocoretinateRelated Search:


  • TOCORETINATE
  • tretinoin tocoferil
  • 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-yl-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate
  • VITAMIN E VITAMIN A ACID ESTER
  • L 300
  • N 021
  • Olcenon
  • Retinoic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, rel- (9CI)
  • Retinoic acid, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-(+-)-
  • Retinoic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, (±)-
  • dl-α-Tocopheryl Retinoate
  • dl-a-Tocopheryl Retinoate
  • 40516-48-1