Tocoretinate

Product Name: Tocoretinate
CAS No.: 40516-48-1
Chemical Name: Tocoretinate
Synonyms: N 021;L 300;Olcenon;TOCORETINATE;tretinoin tocoferil;dl-α-Tocopheryl Retinoate;dl-a-Tocopheryl Retinoate;VITAMIN E VITAMIN A ACID ESTER;Retinoic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, (±)-;Retinoic acid, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-(+-)-
CBNumber: CB8700933
Molecular Formula: C49H76O3
Formula Weight: 713.13
MOL File: 40516-48-1.mol

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Tocoretinate Property

Boiling point:: 761.3±60.0 °C(Predicted)
Density: 0.959±0.06 g/cm3(Predicted)
CAS DataBase Reference: 40516-48-1(CAS DataBase Reference)

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Safety

Toxicity: LD50 in mice (mg/kg): >1000 i.v.; >2000 orally (Fukawa, 1975)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: T526200
Product name: dl-α-TocopherylRetinoate
Packaging: 10mg
Price: $55
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004438
Product name: TOCORETINATE
Purity: 95.00%
Packaging: 250MG
Price: $730
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004438
Product name: TOCORETINATE
Purity: 95.00%
Packaging: 500MG
Price: $1020
Updated: 2021/12/16

AHH

Product number: API-1775
Product name: Tocoretinate
Purity: 98%
Packaging: 1g
Price: $910
Updated: 2021/12/16

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Tocoretinate Chemical Properties,Usage,Production

Description

Tretinoin tocoferil, the a-tocopherol ester of all-trans-retinoic acid, was launched for the treatment of bedsores and skin ulcers such as burn, leg, and diabetic ulcers. It is also an orally active agent for gastric ulcer treatment. Tretinoin tocoferil represents a new class of antiulcer drugs which act by directly promoting tissue repair, distinguished from common drugs that exert an indirect function by suppression of acid-secretion and mucosa protection. The mode of its action has been proposed to relate to its ability to stimulate DNA synthesis of growth-arrested human skin fibroblasts by promoting expression of the epidermal growth factor receptor.

Originator

Nisshin Flour Milling (Japan)

Uses

dl-α-Tocopheryl Retinoate is an α-tocopherol ester of all-trans retinoic acid (R250200) and is safely used in the treatment of skin ulcer. ?dl-α-Tocopheryl Retinoate inhibited proliferation of human promyelocytic leukemia HL-60 cells and induced granulocytic differentiation of the cells, but to a lesser extent than did retinoic acid.

Definition

ChEBI: Tocoretinate is a tocol.

brand name

Olcenon

Tocoretinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Tocoretinate Suppliers

China 27 India 3 United Kingdom 4 United States 12 Global 46

Wuhan Wei Shunda Technology Development Co., Ltd.

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Alway Chem, China

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View Lastest Price from Tocoretinate manufacturers

Career Henan Chemical Co

Product: Tocoretinate 40516-48-1
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-12-31

40516-48-1, TocoretinateRelated Search:

Centchroman Retinoic acid Propyleneglycol alginate Tetrahydropyran 2,2,4-Trimethyl-1,3-pentanediol monoisobutyrate Ethyl 4-hydroxy-3-methoxybenzoate DL-ALPHA-TOCOPHEROL HYDROGEN SUCCINATE 4-Heptyloxyphenol Retinal β-Tocopherol DL-ALPHA-TOCOPHEROL ACETATE Vitamin A D-alpha-Tocopheryl acetate DL-α-Tocopherol D-gamma-Tocopherol Vitamin E 3-Pentadecylphenol 1-(2-BUTENYLOXY)-4-HEXYLOXYBENZENE

TOCORETINATE

tretinoin tocoferil

3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-yl-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate

VITAMIN E VITAMIN A ACID ESTER

L 300

N 021

Olcenon

Retinoic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, rel- (9CI)

Retinoic acid, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-(+-)-

Retinoic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, (±)-

dl-α-Tocopheryl Retinoate

dl-a-Tocopheryl Retinoate

40516-48-1