3,3-Pentamethylene glutarimide
- Product Name
- 3,3-Pentamethylene glutarimide
- CAS No.
- 1130-32-1
- Chemical Name
- 3,3-Pentamethylene glutarimide
- Synonyms
- NSC 400093;3,3-Pentamethylene;Gabapentin Impurity 13;GABAPENTIN INTERMEDIATES;3-AZASPIRO[4.5]DECAN-2-ONE;1,1-Cyclohexane diacetimide;3-PentaMethylene glutariMide;3,3-Pentamethyleneglutarimide;3,3-Pentamethylene glutarimide;3-azaspiro(5,5)undecan-2,4-dione
- CBNumber
- CB8702245
- Molecular Formula
- C10H15NO2
- Formula Weight
- 181.23
- MOL File
- 1130-32-1.mol
3,3-Pentamethylene glutarimide Property
- Melting point:
- 84-89 °C(lit.)
- Boiling point:
- 362.3±11.0 °C(Predicted)
- Density
- 1.14±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 11.71±0.20(Predicted)
- form
- Solid
- color
- White to Off-White
- CAS DataBase Reference
- 1130-32-1(CAS DataBase Reference)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- RTECS
- CM0120000
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- S354279
- Product name
- 3,3-PENTAMETHYLENEGLUTARIMIDE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $185
- Updated
- 2025/07/31
- Product number
- S354279
- Product name
- 3,3-PENTAMETHYLENEGLUTARIMIDE
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $179
- Updated
- 2024/03/01
- Product number
- P271755
- Product name
- 3,3-PentamethyleneGlutarimide
- Packaging
- 2.5g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- P271755
- Product name
- 3,3-PentamethyleneGlutarimide
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- I043
- Product name
- 3,3-Pentamethyleneglutarimide
- Packaging
- 5g
- Price
- $92
- Updated
- 2021/12/16
3,3-Pentamethylene glutarimide Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
Gabapentin intermediate.
Synthesis
4355-11-7
77287-34-4
1130-32-1
To a 100 mL three-necked flask equipped with a thermometer, mechanical stirrer and reflux condenser were added 1,1-cyclohexanediacetic acid (10.0 g, 50 mmol) and formamide (4.5 g, 100 mmol). The reaction mixture was heated and the initial suspension was gradually transformed into a clarified colorless solution, the heating was continued and the reaction was stirred at 150-160 °C for 4 hours. The hot clarified reaction mixture was carefully poured into water (40 mL). The resulting colorless precipitate was collected, washed with water (10 mL) and subsequently dried under vacuum to afford 8.80 g (97% yield) of 3,3-cyclopentanediyl glutarimide as a colorless solid (99.9% purity by HPLC) with a melting point of 168-169 °C (literature value 169-170 °C).1H NMR (300 MHz, DMSO-d6) δ: 10.67 (broad peak, 1H), 2.42 (single peak, 4H), 1.30-1.41 (multiple peaks, 10H); 13C NMR (75 MHz, DMSO-d6) δ: 172.72, 42.50, 35.29, 32.45, 25.36, 20.97. Mass spectrometry (ESI-MS): calculated value (M+H)+ for C10H15NO2: 182.23, measured value: 182.21.
References
[1] Organic Preparations and Procedures International, 2013, vol. 45, # 6, p. 504 - 506
3,3-Pentamethylene glutarimide Preparation Products And Raw materials
Raw materials
Preparation Products
3,3-Pentamethylene glutarimide Suppliers
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View Lastest Price from 3,3-Pentamethylene glutarimide manufacturers
- Product
- 3,3-Pentamethylene glutarimide 1130-32-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 5000KG
- Release date
- 2024-07-18
- Product
- 3,3-Pentamethylene glutarimide 1130-32-1
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10
- Release date
- 2024-07-14
- Product
- 3,3-Pentamethylene glutarimide 1130-32-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-30