Description References
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Octyl gallate

Description References
Product Name
Octyl gallate
CAS No.
1034-01-1
Chemical Name
Octyl gallate
Synonyms
Progallin O;OCTYL GALLATE;N-OCTYL GALLATE;Stabilizer GA-8;OCTYLGALLATE(RG);Gallic acid octyl;n-OctylGallate>Octyl gallate CRS;n-Octyl gallate, 98+%;GALLIC ACID OCTYL ESTER
CBNumber
CB8704027
Molecular Formula
C15H22O5
Formula Weight
282.33
MOL File
1034-01-1.mol
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Octyl gallate Property

Melting point:
101-104 °C(lit.)
Boiling point:
262.5°C (estimate)
Density 
1.0984 (rough estimate)
refractive index 
1.6200 (estimate)
storage temp. 
Store below +30°C.
solubility 
soluble2.5%, clear, colorless (AcOH (MEOH))
form 
Solid
pka
7.94±0.25(Predicted)
color 
White to Off-White
Water Solubility 
20mg/L(29.99 ºC)
BRN 
2132305
LogP
3.660
CAS DataBase Reference
1034-01-1(CAS DataBase Reference)
EPA Substance Registry System
Benzoic acid, 3,4,5-trihydroxy-, octyl ester (1034-01-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-43
Safety Statements 
24-37
WGK Germany 
1
RTECS 
LW8225000
TSCA 
Yes
HS Code 
2918 29 00
Toxicity
LD50 orally in Rabbit: 1960 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
48700
Product name
Octyl gallate
Purity
antioxidant, ≥99.0% (HPLC)
Packaging
50g
Price
$137
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR3511
Product name
Octyl Gallate
Purity
certified reference material, pharmaceutical secondary standard
Packaging
500MG
Price
$243
Updated
2024/03/01
Sigma-Aldrich
Product number
48700
Product name
Octyl gallate
Purity
antioxidant, ≥99.0% (HPLC)
Packaging
250g
Price
$605
Updated
2024/03/01
Sigma-Aldrich
Product number
06717
Product name
Octyl gallate
Purity
analytical standard
Packaging
500mg
Price
$102
Updated
2022/05/15
TCI Chemical
Product number
G0206
Product name
n-Octyl Gallate
Purity
>98.0%(T)
Packaging
25g
Price
$64
Updated
2024/03/01
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Octyl gallate Chemical Properties,Usage,Production

Description

Octyl gallate is the ester formed by 1-octanol and gallic acid. It can be used as an antioxidant and preservative to be supplemented to the food. It has been demonstrated to be an effective fungicide being capable of inhibiting the growth of S. cerevisiae and Z. bailii as it can inhibit the fluidity of the cell membrane through acting as a nonionic surface-active agent. It is also capable of killing both DNA and RNA viruses with a relatively moderate cytotoxicity. For example, it has the potential to treat influenza. Octyl gallate also has certain bactericidal activity, being capable of treating the infections associated with enterococci.

References

[1]Ken-Ichi, Fujita, and K. Isao. "Antifungal activity of octyl gallate. " International Journal of Food Microbiology 79.3(2002):1
[2]Gutiérrez-Fernández, J, et al. "Antimicrobial activity of binary combinations of natural and synthetic phenolic antioxidants against Enterococcus faecalis. " Journal of Dairy Science 96.8(2013):4912-20.93.
[3] Yamasaki, H, et al. "Antiviral effect of octyl gallate against influenza and other RNA viruses. " International Journal of Molecular Medicine 19.4(2007): 685-688.

Description

During the 1940s, propyl gallate and several other alkyl gallates were allowed for use in foods in a number of countries. Since gallic acid contains three phenolic hydroxyl groups, it is a rather potent antioxidant; however, the propyl ester has a significant degree of water solubility. As a consequence, propyl gallate tends to partition into any water phase which may be present and to complex with iron salts to give bluish black colors. Also, its relatively poor resistance to heat degradation makes it ineffective for baking and frying applications. The higher alkyl gallates (butyl and octyl) are more fat soluble.

Chemical Properties

White powder

Uses

Used in treatment of alcohol dependence.

Uses

Octyl gallate is an antioxidant that is used as a preservation agent in a wide variety of foods, oils, and cosmetics.

Uses

Octyl gallate is an antioxidant for use in cosmetic and pharmaceutical products and in food products, such as margarine and peanut butter.

Definition

ChEBI: A gallate ester obtained by condensation of the carboxy group of gallic acid with the hydroxy group of octanol.

General Description

Octyl gallate is an ester of gallic acid which is generally used as an antioxidant in food and pharmaceutical industries. It can act against the oxidative damage caused by reactive oxygen species (ROS) in the form of hydroxyl radicals or hydrogen peroxides, and reactive sulfur species (RSS)

Contact allergens

Octyl gallate, a gallate ester (E 311), is an antioxidant added to food and cosmetics to prevent oxidation of unsaturated fatty acids. Cases were sparsely reported in food industry or from lipsticks. Patch tests are frequently irritant.

Safety Profile

A poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes.

Octyl gallate Preparation Products And Raw materials

Raw materials

Preparation Products

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Octyl gallate Suppliers

Shanghai RC Chemicals Co., Ltd.
Tel
21-58661250 18217085189
Fax
+86-21-58661251
Email
3059772675@qq.com
Country
China
ProdList
104
Advantage
64
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
21-31038972 15721252604
Fax
+86-21-51385350
Email
ammyzuo@harvest-chem.com
Country
China
ProdList
2540
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
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View Lastest Price from Octyl gallate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Octyl Gallate 1034-01-1
Price
US $65.00-20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-31
HebeiShuoshengImportandExportco.,Ltd
Product
Octyl gallate 1034-01-1
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-08
Hebei Longbang Technology Co., Ltd
Product
Octyl gallate 1034-01-1
Price
US $6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20TONS
Release date
2024-05-10

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