Description References
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Octyl gallate

Description References
Product Name
Octyl gallate
CAS No.
1034-01-1
Chemical Name
Octyl gallate
Synonyms
Progallin O;OCTYL GALLATE;N-OCTYL GALLATE;Stabilizer GA-8;OCTYLGALLATE(RG);Gallic acid octyl;n-OctylGallate>Octyl gallate CRS;n-Octyl gallate, 98+%;GALLIC ACID OCTYL ESTER
CBNumber
CB8704027
Molecular Formula
C15H22O5
Formula Weight
282.33
MOL File
1034-01-1.mol
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Octyl gallate Property

Melting point:
101-104 °C(lit.)
Boiling point:
262.5°C (estimate)
Density 
1.0984 (rough estimate)
refractive index 
1.6200 (estimate)
storage temp. 
Store below +30°C.
solubility 
soluble2.5%, clear, colorless (AcOH (MEOH))
form 
Solid
pka
7.94±0.25(Predicted)
color 
White to Off-White
Water Solubility 
20mg/L(29.99 ºC)
BRN 
2132305
LogP
3.660
CAS DataBase Reference
1034-01-1(CAS DataBase Reference)
EPA Substance Registry System
Benzoic acid, 3,4,5-trihydroxy-, octyl ester (1034-01-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-43
Safety Statements 
24-37
WGK Germany 
1
RTECS 
LW8225000
TSCA 
Yes
HS Code 
2918 29 00
Toxicity
LD50 orally in Rabbit: 1960 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
48700
Product name
Octyl gallate
Purity
antioxidant, ≥99.0% (HPLC)
Packaging
50g
Price
$137
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR3511
Product name
Octyl Gallate
Purity
certified reference material, pharmaceutical secondary standard
Packaging
500MG
Price
$243
Updated
2024/03/01
Sigma-Aldrich
Product number
48700
Product name
Octyl gallate
Purity
antioxidant, ≥99.0% (HPLC)
Packaging
250g
Price
$605
Updated
2024/03/01
Sigma-Aldrich
Product number
06717
Product name
Octyl gallate
Purity
analytical standard
Packaging
500mg
Price
$102
Updated
2022/05/15
TCI Chemical
Product number
G0206
Product name
n-Octyl Gallate
Purity
>98.0%(T)
Packaging
25g
Price
$64
Updated
2024/03/01
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Octyl gallate Chemical Properties,Usage,Production

Description

Octyl gallate is the ester formed by 1-octanol and gallic acid. It can be used as an antioxidant and preservative to be supplemented to the food. It has been demonstrated to be an effective fungicide being capable of inhibiting the growth of S. cerevisiae and Z. bailii as it can inhibit the fluidity of the cell membrane through acting as a nonionic surface-active agent. It is also capable of killing both DNA and RNA viruses with a relatively moderate cytotoxicity. For example, it has the potential to treat influenza. Octyl gallate also has certain bactericidal activity, being capable of treating the infections associated with enterococci.

References

[1]Ken-Ichi, Fujita, and K. Isao. "Antifungal activity of octyl gallate. " International Journal of Food Microbiology 79.3(2002):1
[2]Gutiérrez-Fernández, J, et al. "Antimicrobial activity of binary combinations of natural and synthetic phenolic antioxidants against Enterococcus faecalis. " Journal of Dairy Science 96.8(2013):4912-20.93.
[3] Yamasaki, H, et al. "Antiviral effect of octyl gallate against influenza and other RNA viruses. " International Journal of Molecular Medicine 19.4(2007): 685-688.

Description

During the 1940s, propyl gallate and several other alkyl gallates were allowed for use in foods in a number of countries. Since gallic acid contains three phenolic hydroxyl groups, it is a rather potent antioxidant; however, the propyl ester has a significant degree of water solubility. As a consequence, propyl gallate tends to partition into any water phase which may be present and to complex with iron salts to give bluish black colors. Also, its relatively poor resistance to heat degradation makes it ineffective for baking and frying applications. The higher alkyl gallates (butyl and octyl) are more fat soluble.

Chemical Properties

White powder

Uses

Used in treatment of alcohol dependence.

Uses

Octyl gallate is an antioxidant that is used as a preservation agent in a wide variety of foods, oils, and cosmetics.

Uses

Octyl gallate is an antioxidant for use in cosmetic and pharmaceutical products and in food products, such as margarine and peanut butter.

Definition

ChEBI: A gallate ester obtained by condensation of the carboxy group of gallic acid with the hydroxy group of octanol.

General Description

Octyl gallate is an ester of gallic acid which is generally used as an antioxidant in food and pharmaceutical industries. It can act against the oxidative damage caused by reactive oxygen species (ROS) in the form of hydroxyl radicals or hydrogen peroxides, and reactive sulfur species (RSS)

Contact allergens

Octyl gallate, a gallate ester (E 311), is an antioxidant added to food and cosmetics to prevent oxidation of unsaturated fatty acids. Cases were sparsely reported in food industry or from lipsticks. Patch tests are frequently irritant.

Safety Profile

A poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes.

Octyl gallate Preparation Products And Raw materials

Raw materials

Preparation Products

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Octyl gallate Suppliers

Americas 1 Belgium 2 China 266 Europe 1 France 3 Germany 8 India 10 Japan 3 Slovakia 1 South Korea 1 Switzerland 1 United Kingdom 8 United States 46 Global 351
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View Lastest Price from Octyl gallate manufacturers

Hebei Longbang Technology Co., Ltd
Product
Octyl gallate 1034-01-1
Price
US $6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20TONS
Release date
2024-05-10
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Octyl Gallate 1034-01-1
Price
US $65.00-20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-31
HebeiShuoshengImportandExportco.,Ltd
Product
Octyl gallate 1034-01-1
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-08

1034-01-1, Octyl gallateRelated Search:

octyl benzoate 2'-Hydroxy-3-phenylpropiophenone 2,3,4-Trihydroxybenzoic acid Gallic acid monohydrate 4-Hydroxybenzoic acid Pyrogallol Salicylic acid Acetic acid octyl ester 2-ETHYLHEXYL PALMITATE Propyl gallate 4-HYDROXYBENZOIC ACID N-AMYL ESTER Methylparaben Methyl gallate galloylpaeoniflorin Pyrimidine-2-carboxylic acid 9-Fluorenylmethyl chloroformate Gallic acid Ethyl gallate

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