3,5-Bis(trifluoromethyl)benzyl bromide
- Product Name
- 3,5-Bis(trifluoromethyl)benzyl bromide
- CAS No.
- 32247-96-4
- Chemical Name
- 3,5-Bis(trifluoromethyl)benzyl bromide
- Synonyms
- 1-(BROMOMETHYL)-3,5-BIS(TRIFLUOROMETHYL)BENZENE;5-Bis(trifluoroMethyl)benzyl broMide;3,5-Bis(trifluoremethyl)benzylbromide;3,5-BIS(TRIFLUOROMETHYL)BENZYL BROMIDE;3,5-DI(TRIFLUORO METHYL)BENZYL BROMIDE;3,5-Bis(trifluoromethyl)benzylbromiode;3,5-Bis(trifluoromethyl)benzylbromide98%;3,5-Bis(trifluoromethyl)benzyl bromide 98%;3,5-Bis(trifluoromethyl)benzyl Bromide >3,5-Bis(trifluoromethyl)benzyl bromide, 97+%
- CBNumber
- CB8709789
- Molecular Formula
- C9H5BrF6
- Formula Weight
- 307.03
- MOL File
- 32247-96-4.mol
3,5-Bis(trifluoromethyl)benzyl bromide Property
- Melting point:
- 18°C
- Boiling point:
- 136-140°C 14mm
- Density
- 1.675 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.445(lit.)
- Flash point:
- 79 °F
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Difficult to mix.
- form
- Liquid
- Specific Gravity
- 1.675
- color
- Clear colorless to yellow-brown
- Sensitive
- Lachrymatory
- BRN
- 656506
- CAS DataBase Reference
- 32247-96-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 3,5-Bis(trifluoromethyl)benzyl bromide(32247-96-4)
Safety
- Hazard Codes
- C,F
- Risk Statements
- 10-34
- Safety Statements
- 26-36/37/39-45-25-16
- RIDADR
- UN 2920 8/PG 2
- WGK Germany
- 3
- Hazard Note
- Corrosive/Lachrymatory
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29039990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 263397
- Product name
- 3,5-Bis(trifluoromethyl)benzyl bromide
- Purity
- 97%
- Packaging
- 1g
- Price
- $26.5
- Updated
- 2024/03/01
- Product number
- 263397
- Product name
- 3,5-Bis(trifluoromethyl)benzyl bromide
- Purity
- 97%
- Packaging
- 5g
- Price
- $63
- Updated
- 2024/03/01
- Product number
- B1867
- Product name
- 3,5-Bis(trifluoromethyl)benzyl Bromide
- Purity
- >96.0%(GC)
- Packaging
- 5g
- Price
- $37
- Updated
- 2024/03/01
- Product number
- B1867
- Product name
- 3,5-Bis(trifluoromethyl)benzyl Bromide
- Purity
- >96.0%(GC)
- Packaging
- 25g
- Price
- $146
- Updated
- 2024/03/01
- Product number
- A19590
- Product name
- 3,5-Bis(trifluoromethyl)benzyl bromide, 98%
- Packaging
- 1g
- Price
- $37.6
- Updated
- 2021/12/16
3,5-Bis(trifluoromethyl)benzyl bromide Chemical Properties,Usage,Production
Chemical Properties
White or Colorles to Yellow to Orange powder to lump to clear liquid
Uses
3,5-Bis(trifluoromethyl)benzyl bromide is used as derivatization reagent in detection of uracil in DNA by GC and negative chemical ionization mass spectrometry in enantioselective synthesis of non-peptidic neurokinin NK1 receptor antagonist.
Synthesis
Synthesis of 3, 5-bis (trifluoromethyl)-benzyl bromide:
In a 4-neck flask with capacity 1000 ml equipped with mechanical agitator, thermometer, bubble condenser and 100 ml loading funnel, 262.2 g of the product of Example 1 (ii) at 92. 8% (0. 988 moles), 550,2 g HBr 48% (3.2645 moles) are loaded; this is heated at 50°C so as to melt the alcohol, then one starts to dose 113 g of concentrated His04 (1.153 moles). Pouring is accomplished in 30 minutes, noting an increase of the internal temperature. This is heated to 100-105°C and left to react for 8 hours. The reaction is completed by reflux heating for per 1.5 hours. the mixture is left to settle and the phases are separated; the solvents are removed from the organic phase and the product in the title is obtained with a yield of 99.1 %.
3,5-Bis(trifluoromethyl)benzyl bromide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,5-Bis(trifluoromethyl)benzyl bromide manufacturers
- Product
- 3,5-Bis(trifluoromethyl)benzyl bromide 32247-96-4
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-25
- Product
- 3,5-Bis(trifluoromethyl)benzyl bromide 32247-96-4
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 500
- Release date
- 2019-09-01