2-FLUORO-4-IODO-3-PICOLINE

Product Name: 2-FLUORO-4-IODO-3-PICOLINE
CAS No.: 153034-80-1
Chemical Name: 2-FLUORO-4-IODO-3-PICOLINE
Synonyms: 2-FLUORO-4-IODO-3-PICOLINE;2-Fluoro-4-iodo-3-methylpyridine;Pyridine, 2-fluoro-4-iodo-3-methyl-;2-FLUORO-4-IODO-3-PICOLINE ISO 9001：2015 REACH
CBNumber: CB8748542
Molecular Formula: C6H5FIN
Formula Weight: 237.01
MOL File: 153034-80-1.mol

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2-FLUORO-4-IODO-3-PICOLINE Property

Boiling point:: 244℃
Density: 1.892
Flash point:: 101℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: -1.53±0.18(Predicted)
Appearance: White to off-white Solid

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F598828
Product name: 2-Fluoro-4-iodo-3-picoline
Packaging: 250mg
Price: $65
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: Y14225
Product name: 2-Fluoro-4-iodo-3-methylpyridine
Purity: 95%
Packaging: 5g
Price: $70
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: Y14225
Product name: 2-Fluoro-4-iodo-3-methylpyridine
Purity: 95%
Packaging: 1g
Price: $20
Updated: 2021/12/16

AK Scientific

Product number: N391
Product name: 2-Fluoro-4-iodo-3-picoline
Packaging: 250mg
Price: $29
Updated: 2021/12/16

ChemScene

Product number: CS-W021692
Product name: 2-Fluoro-4-iodo-3-picoline
Packaging: 1g
Price: $50
Updated: 2021/12/16

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2-FLUORO-4-IODO-3-PICOLINE Chemical Properties,Usage,Production

Synthesis

113975-22-7

74-88-4

153034-80-1

General procedure for the synthesis of 2-fluoro-3-methyl-4-iodopyridine from 2-fluoro-3-iodopyridine and iodomethane: A THF solution of 2-fluoro-3-iodopyridine (30 g, 135 mmol) was slowly added to a THF solution of LDA (68 mL, 135 mmol) in THF (100 mL) at -78 °C under nitrogen protection, maintaining the temperature at -78 °C and stirring for 1 hour. Subsequently, iodomethane (25 mL, 405 mmol) was added to the reaction system and stirring was continued at -78 °C for 30 min. Upon completion of the reaction, the reaction was quenched with saturated aqueous NaHCO3 solution and NaHCO3 solution at -78 °C was added. The reaction mixture was extracted with ether and the combined organic phases were dried over MgSO4 and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent ratio petroleum ether:EtOAc = 4:1) to afford 2-fluoro-3-methyl-4-iodopyridine as a brown solid (22 g, 69% yield).MS (ES+) analysis showed that the theoretical value of C6H5FIN was 237 and the measured value was 238 [M + H]+ .

References

[1] Journal of Organic Chemistry, 1993, vol. 58, # 27, p. 7832 - 7838
[2] Tetrahedron, 2004, vol. 60, # 29, p. 6113 - 6120
[3] Tetrahedron Letters, 1995, vol. 36, # 44, p. 7995 - 7998
[4] Patent: US2017/342078, 2017, A1. Location in patent: Paragraph 0412; 0413
[5] Patent: US5496952, 1996, A

2-FLUORO-4-IODO-3-PICOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-FLUORO-4-IODO-3-PICOLINE Suppliers

China 115 Germany 3 India 2 United Kingdom 2 United States 15 Global 137

J & K SCIENTIFIC LTD.

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Energy Chemical

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View Lastest Price from 2-FLUORO-4-IODO-3-PICOLINE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 2-FLUORO-4-IODO-3-PICOLINE 153034-80-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-14

Honest Joy Holdings Limited

Product: 2-Fluoro-4-iodo-3-picoline 153034-80-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.0%
Supply Ability: 100 tons
Release date: 2022-02-08

Dideu Industries Group Limited

Product: 2-FLUORO-4-IODO-3-PICOLINE 153034-80-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-01

153034-80-1, 2-FLUORO-4-IODO-3-PICOLINERelated Search:

4-Iodo-3-methylpyridine 4-Iodopyridine 2-FLUORO-4-IODO-6-PICOLINE Pyridine, 2-fluoro-5-iodo-4-methyl- 2-FLUORO-4-IODO-3-PICOLINE 4-IODO-2-FLUORO-3-FORMYLPYRIDINE 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE 2-FLUORO-4-IODONICOTINIC ACID 2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER 2-FLUORO-3-IODO-5-PICOLINE (2-FLUORO-3-IODO-5-METHYLPYRIDINE),2-FLUORO-3-IODO-5-PICOLINE 2-FLUORO-4-IODO-5-PICOLINE (2-FLUORO-4-IODO-5-METHYLPYRIDINE),6-Fluoro-4-iodo-b-picoline,2-FLUORO-4-IODO-5-PICOLINE 3-CHLORO-6-FLUORO-4-IODO-2-PICOLINE 3-BROMO-2-FLUORO-4-IODO-6-PICOLINE 2-Chloro-3-Fluoro-5-Iodo-4-Picoline 2-FLUORO-5-IODO-3-PICOLINE 2-CHLORO-5-FLUORO-4-IODO-3-PICOLINE 3-BROMO-6-FLUORO-4-IODO-2-PICOLINE 6-FLUORO-3-IODO-2-PICOLINE

2-FLUORO-4-IODO-3-PICOLINE

2-Fluoro-4-iodo-3-methylpyridine

Pyridine, 2-fluoro-4-iodo-3-methyl-

2-FLUORO-4-IODO-3-PICOLINE ISO 9001：2015 REACH

153034-80-1

Boronic Acid

Pyridines

Pyridine