2-CHLORO-5-METHOXYPYRIDINE
- Product Name
- 2-CHLORO-5-METHOXYPYRIDINE
- CAS No.
- 139585-48-1
- Chemical Name
- 2-CHLORO-5-METHOXYPYRIDINE
- Synonyms
- 2-CHLORO-5-METHOXYPYRIDINE;Pyridine, 2-chloro-5-methoxy-;2-Chloro-5-methoxypyridine 98%;Pyridine, 2-chloro-5-methoxy- (9CI);China biggest manufacturer 2-CHLORO-5-METHOXYPYRIDINE 139585-48-1
- CBNumber
- CB8760810
- Molecular Formula
- C6H6ClNO
- Formula Weight
- 143.57
- MOL File
- 139585-48-1.mol
2-CHLORO-5-METHOXYPYRIDINE Property
- Boiling point:
- 213.7±20.0℃ (760 Torr)
- Density
- 1.210±0.06 g/cm3 (20 ºC 760 Torr)
- Flash point:
- 83.1±21.8℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- -2.22±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- C381298
- Product name
- 2-Chloro-5-methoxypyridine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FC55606
- Product name
- 2-Chloro-5-methoxypyridine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 4H56-5-9D
- Product name
- 2-Chloro-5-methoxypyridine
- Packaging
- 1g
- Price
- $77
- Updated
- 2021/12/16
- Product number
- Y15335
- Product name
- 2-Chloro-5-methoxypyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- J98611
- Product name
- 2-Chloro-5-methoxypyridine
- Packaging
- 1g
- Price
- $49
- Updated
- 2021/12/16
2-CHLORO-5-METHOXYPYRIDINE Chemical Properties,Usage,Production
Chemical Properties
Colorless to light yellow liquid
Synthesis
41288-96-4
74-88-4
139585-48-1
4) Synthesis of 2-chloro-5-methoxypyridine: 2-chloro-5-hydroxypyridine (1.30 g) and iodomethane (1.25 mL) were dissolved in N,N-dimethylformamide (26 mL) under nitrogen protection. Subsequently, a methanolic solution of 28% sodium methanol (2.0 mL) was added slowly and dropwise to this solution. The reaction mixture was stirred at room temperature for 1.5 hours. Upon completion of the reaction, the mixture was extracted by adding saturated aqueous ammonium chloride solution and ethyl acetate to the mixture. After separation of the organic phase, it was washed with saturated brine and dried with anhydrous magnesium sulfate. After filtration to remove the desiccant, the solvent was removed by concentration under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: hexane-ethyl acetate gradient) to afford 2-chloro-5-methoxypyridine (1.40 g, 98% yield) as a white solid. The product was confirmed by 1H-NMR (400 MHz, CDCl3): δ 3.85 (3H, s), 7.17-7.25 (2H, m), 8.05 (1H, d, J = 2.9 Hz). LC-MS analysis showed m/z: 144 ([M+H]+).
References
[1] Patent: EP1698626, 2006, A1. Location in patent: Page/Page column 24
[2] Patent: US2010/240634, 2010, A1. Location in patent: Page/Page column 74
[3] European Journal of Inorganic Chemistry, 2015, vol. 2015, # 28, p. 4666 - 4677
[4] Journal of Medicinal Chemistry, 2014, vol. 57, # 6, p. 2462 - 2471
[5] Chemische Berichte, 1992, vol. 125, # 5, p. 1131 - 1140
2-CHLORO-5-METHOXYPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-CHLORO-5-METHOXYPYRIDINE Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
- Tel
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- Fax
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- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
- Tel
- --
- Fax
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- Country
- United Kingdom
- ProdList
- 6565
- Advantage
- 38
View Lastest Price from 2-CHLORO-5-METHOXYPYRIDINE manufacturers
- Product
- 2-CHLORO-5-METHOXYPYRIDINE 139585-48-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-18
- Product
- 2-Chloro-5-methoxypyridine 139585-48-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 100kgs
- Release date
- 2024-09-04
- Product
- 2-CHLORO-5-METHOXYPYRIDINE 139585-48-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-20