4-Methyl-3-nitropyridine

Product Name: 4-Methyl-3-nitropyridine
CAS No.: 5832-44-0
Chemical Name: 4-Methyl-3-nitropyridine
Synonyms: 3-nitro-4-picoline;4-METHYL-3-NITROPYRIDINE;3-Nitro-4-methylpyridine;Methyl-3-nitropyridine,4-;pyridine, 4-Methyl-3-nitro-;4-Methyl-3-nitropyridine>4-Methyl-3-nitropyridine 97%;4-Methyl-3-nitropyridine,98%;Pyridine, 4-methyl-3-nitro- (9CI);4-Methyl-3-nitropyridine ISO 9001：2015 REACH
CBNumber: CB8769909
Molecular Formula: C6H6N2O2
Formula Weight: 138.12
MOL File: 5832-44-0.mol

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4-Methyl-3-nitropyridine Property

Melting point:: 24-28 °C
Boiling point:: 238 °C
Density: 1.228 g/mL at 25 °C
refractive index: n20/D 1.549
Flash point:: 227 °F
storage temp.: Inert atmosphere,Room Temperature
form: powder to lump to clear liquid
pka: 1.87±0.18(Predicted)
color: White or Colorless to Yellow
BRN: 118796
InChI: InChI=1S/C6H6N2O2/c1-5-2-3-7-4-6(5)8(9)10/h2-4H,1H3
InChIKey: JLNRJMGYBKMDGI-UHFFFAOYSA-N
SMILES: C1=NC=CC(C)=C1[N+]([O-])=O
CAS DataBase Reference: 5832-44-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,T,Xi
Risk Statements: 22-37/38-41-36/37/38
Safety Statements: 26-39-36
RIDADR: 2810
WGK Germany: 3
Hazard Note: Harmful
HazardClass: 6.1
PackingGroup: III
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 532592
Product name: 4-Methyl-3-nitropyridine
Purity: 97%
Packaging: 1g
Price: $52.7
Updated: 2023/06/20

Sigma-Aldrich

Product number: 532592
Product name: 4-Methyl-3-nitropyridine
Purity: 97%
Packaging: 5g
Price: $219
Updated: 2023/06/20

TCI Chemical

Product number: M2353
Product name: 4-Methyl-3-nitropyridine
Purity: >97.0%(GC)
Packaging: 1g
Price: $56
Updated: 2023/06/20

TCI Chemical

Product number: M2353
Product name: 4-Methyl-3-nitropyridine
Purity: >97.0%(GC)
Packaging: 5g
Price: $188
Updated: 2023/06/20

TRC

Product number: M220645
Product name: 4-Methyl-3-nitropyridine
Packaging: 1g
Price: $75
Updated: 2021/12/16

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4-Methyl-3-nitropyridine Chemical Properties,Usage,Production

Chemical Properties

Deliquescent cryst

Uses

4-Methyl-3-nitropyridine may be used as a starting material in the synthesis of ethyl 6-azaindole-2-carboxylate and also 3-substituted azaindoles.

Uses

4-METHYL-3-NITROPYRIDINE is a useful research chemical.

General Description

4-Methyl-3-nitropyridine, a substituted nitropyridine, can be prepared by the malonation of 4-methoxy-3-nitropyridine with sodium diethyl malonate.

Synthesis

108-89-4

5832-44-0

The general procedure for synthesizing 3-nitro-4-methylpyridine from 4-methylpyridine is as follows:1) In step 1) of Example 1, prepare a reaction solution by adding 60 g of nitrogen pentoxide solid to 300 g of liquid sulfur dioxide at -30° C. and stirring sufficiently until completely dissolved.2) Dissolve 30 g of 4-methylpyridine in 120 g of liquid sulfur dioxide and maintain the temperature at -30° C.3 ) Slowly drop the reaction solution into 300 g of ice water for 5 minutes. ) Slowly add the nitrogen pentoxide-sulfur dioxide solution prepared in step 1) dropwise to the 4-methylpyridine solution, and react for 5 min. 4) Slowly pour the reaction solution into 300 g of ice water, and hydrolyze thoroughly. 5) Adjust the pH of the hydrolyzed solution to 8-9 using sodium carbonate. 6) Add 290 g of toluene for two extractions, and combine the extracts. 7) Remove the solvent by vacuum distillation to obtain 39 g of 3- Nitro-4-methylpyridine. The purity of the product was 99.0% by gas chromatography.

References

[1] Organic and Biomolecular Chemistry, 2005, vol. 3, # 3, p. 538 - 541
[2] Acta Chemica Scandinavica, 1994, vol. 48, # 12, p. 1001 - 1006
[3] Acta Chemica Scandinavica, 1994, vol. 48, # 2, p. 181 - 182
[4] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995, # 6, p. 1211 - 1216
[5] Acta Chemica Scandinavica, 1996, vol. 50, # 6, p. 556 - 557

4-Methyl-3-nitropyridine Preparation Products And Raw materials

Raw materials

4-Methylpyridine Sodium sulfate Trifluoroacetic acid Trifluoroacetic anhydride Ethyl acetate Nitric acid Dichloromethane Sodium hydroxide PETROLEUM ETHER Sodium metabisulfite Potassium nitrate

Preparation Products

3-NITROISONICOTINALDEHYDE

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4-Methyl-3-nitropyridine Suppliers

Americas 1 China 204 Europe 2 Germany 4 India 9 Japan 1 Switzerland 1 United Kingdom 10 United States 29 Global 261

Shijiazhuang suchen Chemical Technology Co. LTD

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View Lastest Price from 4-Methyl-3-nitropyridine manufacturers

TAIZHOU DKD CHEMICAL CO., LTD.

Product: 4-Methyl-3-nitropyridine 5832-44-0
Price: US $0.00/kg
Min. Order: 25kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2022-11-08

Dideu Industries Group Limited

Product: 4-Methyl-3-nitropyridine 5832-44-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Methyl-3-nitropyridine 5832-44-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

5832-44-0, 4-Methyl-3-nitropyridineRelated Search:

2,4,6-Collidine 2-Chloro-5-chloromethylpyridine 2,6-Lutidine METHYL THIOPHENE-2-CARBOXYLATE Methyl acetate Azamethiphos 4-Methylpyridine Bensulfuron methyl 3-Nitropyridine 2-Methyl-3-nitropyridine Kresoxim-methyl Methylparaben Methyl acrylate Thiophanate-methyl Methyl Parathion-methyl nitrotoluene 2-AMINO-3-NITRO-4-PICOLINE (2-AMINO-4-METHYL-3-NITROPYRIDINE)

4-METHYL-3-NITROPYRIDINE

pyridine, 4-Methyl-3-nitro-

3-Nitro-4-methylpyridine

3-nitro-4-picoline

Pyridine, 4-methyl-3-nitro- (9CI)

Methyl-3-nitropyridine,4-

4-Methyl-3-nitropyridine,98%

4-Methyl-3-nitropyridine 97%

4-Methyl-3-nitropyridine&gt

4-Methyl-3-nitropyridine ISO 9001：2015 REACH

5832-44-0

5932-44-0

Building Blocks

Pyridines

Heterocyclic Building Blocks

C6

Heterocycle-Pyridine series

NITRO

Pyridine series

Pyridine

Heterocyclic Building Blocks

Pyridines

C6