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1-Hydroxybenzotriazole hydrate

Product Name
1-Hydroxybenzotriazole hydrate
CAS No.
123333-53-9
Chemical Name
1-Hydroxybenzotriazole hydrate
Synonyms
1-HYDROXYBENZOTRIAZOLE MONOHYDRATE;HOBT H2O;HOBT HYDRATE;HOBT.H20;1H-benzo[d][1,2,3]triazol-1-ol hydrate;N-HYDROXYBENZOTRIAZOLE HYDRATE;HOBTM;e hydrate;HOBT MONOHYDRATE;TIMTEC-BB SBB000114
CBNumber
CB8775919
Molecular Formula
C6H7N3O2
Formula Weight
153.14
MOL File
123333-53-9.mol
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1-Hydroxybenzotriazole hydrate Property

Melting point:
155-158 °C(lit.)
Boiling point:
248.8°C (rough estimate)
Density 
1.065 g/cm
refractive index 
1.6910 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMF: 100 mg/mL, clear
form 
Solid
color 
White to Off-White
Water Solubility 
slightly soluble
BRN 
4515
Stability:
Hygroscopic
CAS DataBase Reference
123333-53-9(CAS DataBase Reference)
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Safety

Hazard Codes 
F
Risk Statements 
5-11-R5-R11-44-1
Safety Statements 
15-16-35-7/9-33-S7/9-S33-S16-60-37-26
RIDADR 
UN 3380 4.1/PG 1
WGK Germany 
-
F 
4.10-8
Hazard Note 
Highly Flammable
HS Code 
29339980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H319Causes serious eye irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P230Keep wetted with …

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P380+P375in case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
157260
Product name
1-Hydroxybenzotriazole hydrate
Purity
wetted with not less than 14 wt. % water, 97%
Packaging
25g
Price
$81.1
Updated
2024/03/01
Sigma-Aldrich
Product number
157260
Product name
1-Hydroxybenzotriazole hydrate
Purity
wetted with not less than 14 wt. % water, 97%
Packaging
100g
Price
$191
Updated
2024/03/01
Sigma-Aldrich
Product number
711489
Product name
1-Hydroxybenzotriazole hydrate
Purity
wetted with not less than 20 wt. % water, 97%
Packaging
50g
Price
$133
Updated
2024/03/01
Sigma-Aldrich
Product number
711489
Product name
1-Hydroxybenzotriazole hydrate
Purity
wetted with not less than 20 wt. % water, 97%
Packaging
250g
Price
$450
Updated
2024/03/01
Sigma-Aldrich
Product number
711489
Product name
1-Hydroxybenzotriazole hydrate
Purity
wetted with not less than 20 wt. % water, 97%
Packaging
1kg
Price
$1400
Updated
2024/03/01
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1-Hydroxybenzotriazole hydrate Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

1-Hydroxybenzotriazole hydrate can be used as a condensation reagent to prepare:

  • Poly-γ-glutamic acid methyl ester from a dimer of γ-glutamic acid.
  • Oxadiazoles via cyclo condensation of amidoximes with trifluoroacetic anhydride or benzoic acid derivatives.

Uses

A common additive for peptide coupling.

Uses

additive for oligonucleotide couplings and in racemization-free peptide couplings

General Description

1-Hydroxybenzotriazole is a coupling reagent used to synthesize amides by the condensation reaction between the activated ester/acid and the amino group of protected amino acids. It is also used as a racemization suppressor during peptide synthesis.

1-Hydroxybenzotriazole hydrate Preparation Products And Raw materials

Raw materials

4-Methylmorpholine

Preparation Products

Cefodizime
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1-Hydroxybenzotriazole hydrate Suppliers

Austria 1 Belgium 2 Canada 2 China 316 Europe 4 France 2 Germany 6 India 25 Israel 2 Japan 7 Russia 1 Slovakia 1 South Korea 2 Switzerland 2 The Netherlands 1 United Kingdom 19 United States 50 Global 443
Luxembourg Bio Technologies
Tel
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Fax
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Email
yoav@luxembourg-bio.com
Country
Israel
ProdList
58
Advantage
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LUXEMBOURG INDUSTRIES LTD.
Tel
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Fax
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Email
main@peptide-and-dna.com
Country
Israel
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51
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View Lastest Price from 1-Hydroxybenzotriazole hydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
1-Hydroxybenzotriazole hydrate 123333-53-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-03
Hebei Yanxi Chemical Co., Ltd.
Product
1-Hydroxybenzotriazole hydrate 123333-53-9
Price
US $30.00-10.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-11-22
Hebei Weibang Biotechnology Co., Ltd
Product
1-Hydroxybenzotriazole hydrate 123333-53-9
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-23

123333-53-9, 1-Hydroxybenzotriazole hydrateRelated Search:

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  • 1-Hydroxybenzotriazole hydrate wetted with not less than 20 wt. % water, 97%
  • 1-Hydroxybenzotriazole hydrate HOBT hydrate
  • 1-Hydroxybenzotriazole hydrate >=97.0% (T)
  • HOBT monohydrate (1-hydroxybenzotriazole.H2O)
  • 1-Hydroxybenzotriazole hydrate(< 5 ppm hydrazine)wetted with not less than 20 wt. % water≥ 99% (HPLC)
  • HOBt hydrate (<5 ppm hydrazine)
  • N-HYDROXYBENZOTRIAZOL MONOHYDRATE
  • N-HYDROXYBENZOTRIAZOLE MONOHYDRATE
  • N-HYDROXYBENZOTRIAZOLE HYDRATE
  • N-HYDROXYBENZOTRIAZOLE H2O
  • TIMTEC-BB SBB000114
  • e hydrate
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  • 1-Hydroxybenzotriazole hydrate, ca. 6% water, 98%
  • Hydroxy-1,2,3-Benzotriazole 2592-95-2
  • 1-HYDROXY BENZOTRIAZOLE MONOHYDATE
  • HOBt(hydrate) N-Hydroxybenzotnazole Hydrate
  • 1-HYDROXYBENZOTRIAZOLE HYDRATE (WATER CONTENT BETWEEN 10-13%)
  • 1-Hydroxybenzotriazole Monohydrous
  • 1-Hydroxybenzotriazole Hyrate
  • 1-Hydroxybenzotriazole hydrate, contains 11-16% water, 98%
  • 1-Hydroxybenzotriazole (HOBt) hydrate
  • 1-Hydroxybenzotriazole hydrate (HOBt)
  • N-Hydroxybenzotriazole monohydrate (HOBt)
  • 1-Hydroxy-1H-benzotriazole Hydrate
  • 1-Oxy-benztriazol Hydrate
  • Benzotriazol-1-ol Hydrate
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  • 1-Hydroxybenzotriazole hydrate ,99%
  • 1-HYDROXYBENZOTRIAZOLE HYDRATE, 98%, CONTAINS 11-16% WATER
  • HOBT.H20
  • 1-Hydroxybenzotriazole hydrate ,98%
  • N-Hydroxybenzotrizole Monohydrate
  • 1H-1,2,3-benzotriazole-1,4-diol
  • 1H-1,2,3-BENZOTRIAZOL-1-OL HYDRATE
  • 1H-BENZOTRIAZOLE, 1-HYDROXY-, HYDRATE
  • 1-HYDROXYBENZOTRIAZOL MONOHYDRATE
  • 1-HYDROXYBENZOTRIAZOLE N-HYDRATE
  • 1-HYDROXYBENZOTRIAZOLE MONOHYDRATE
  • 1-HYDROXYBENZOTRIAZOLE HYDRATE
  • HOBT MONOHYDRATE
  • HOBT hydrate [1-Hydroxybenzotriazole hydrate]
  • 1-Hydroxybenzotriazole Hydrat
  • HOBT.H20 1-Hydroxybenzotriazole hydrate
  • 1,2,3-BENZOTRIAZOL-1-OL MONOHYDRATE
  • HOBT.H20 1-Hydroxybenzotriazole hydrate,≥97.0%
  • 1-Hydroxybenzotriazole hydrate USP/EP/BP
  • HoBt.H2O [ 123333-53-9
  • HOBT,1-Hydroxybenzotriazole hydrate
  • HOBT Monohydrate pure, 99%