7-Quinolinecarboxylic acid

Product Name: 7-Quinolinecarboxylic acid
CAS No.: 1078-30-4
Chemical Name: 7-Quinolinecarboxylic acid
Synonyms: AKOS BBS-00005341;7-Carboxyquinoline;quinolin-7-carboxylic acid;7-QUINOLINECARBOXYLIC ACID;QUINOLINE-7-CARBOXYLIC ACID;7-QUINOLINEcarboxylic acid 98%;7-Quinolinecarboxylic acid ,98%;7-Quinolinecarboxylic acid, 95+%;7-Quinolinecarboxylic acid ISO 9001：2015 REACH;7-Carboxyquinoline, 7-Carboxy-1-azanaphthalene
CBNumber: CB8782805
Molecular Formula: C10H7NO2
Formula Weight: 173.17
MOL File: 1078-30-4.mol

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7-Quinolinecarboxylic acid Property

Melting point:: 249.5°C
Boiling point:: 303.81°C (rough estimate)
Density: 1.2427 (rough estimate)
refractive index: 1.5200 (estimate)
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 2.68±0.30(Predicted)
color: Off-white
InChI: InChI=1S/C10H7NO2/c12-10(13)8-4-3-7-2-1-5-11-9(7)6-8/h1-6H,(H,12,13)
InChIKey: WXXVQWSDMOAHHV-UHFFFAOYSA-N
SMILES: N1C2C(=CC=C(C(O)=O)C=2)C=CC=1

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Safety

Safety Statements: 24/25
HS Code: 29334900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific

Product number: OR17564
Product name: Quinoline-7-carboxylic acid
Packaging: 250mg
Price: $34
Updated: 2021/12/16

AK Scientific

Product number: X8858
Product name: 7-Quinolinecarboxylicacid
Packaging: 250mg
Price: $100
Updated: 2021/12/16

Apolloscientific

Product number: OR17564
Product name: Quinoline-7-carboxylic acid
Packaging: 1g
Price: $102
Updated: 2021/12/16

AK Scientific

Product number: X8858
Product name: 7-Quinolinecarboxylicacid
Packaging: 1g
Price: $166
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK108388
Product name: 7-Quinolinecarboxylicacid
Packaging: 1g
Price: $243
Updated: 2021/12/16

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7-Quinolinecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Off-white powder

Uses

7-Quinolinecarboxylic acid is a reactant used in the chemical & genetic engineering of selective ion channel-ligand interactions.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 2721, 1946 DOI: 10.1021/ja01216a093

Synthesis

51552-68-2

1078-30-4

Step 1: An aqueous solution (50 mL) of lithium hydroxide monohydrate (5.42 g, 141 mmol, 3.0 equiv) was slowly added to a tetrahydrofuran solution (200 mL) of methyl 7-quinolinecarboxylate (8.8 g, 47 mmol). The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the tetrahydrofuran was removed by distillation under reduced pressure. To the remaining aqueous phase, 1N aqueous hydrochloric acid solution (141 mL) was slowly added and the pH was adjusted to 7, at which time a white precipitate was produced. The precipitate was collected by filtration and washed sequentially with water and heptane. The resulting solid was dried in a vacuum oven at 50 °C to give 7-quinolinecarboxylic acid (8.4 g, 100% yield) as a white solid. Liquid chromatography analysis (detection wavelength 215 nm): retention time 0.66 min, purity 100%. Mass spectrum (electrospray positive ion mode): m/z 174 ([M+H]+). 1H NMR (400 MHz, d6-DMSO): δ 9.02 (1H, dd), 8.58 (1H, s), 8.48 (1H, d), 8.09 (2H, m), 7.66 (1H, dd).

References

[1] Patent: US2007/60567, 2007, A1. Location in patent: Page/Page column 27

7-Quinolinecarboxylic acid Preparation Products And Raw materials

Raw materials

3-Fluoroaniline m-Toluidine Chromium(VI) oxide Glycerol Sodium iodide Ethyl acetate Acetic acid Sodium hydroxide Sulfuric acid

Preparation Products

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7-Quinolinecarboxylic acid Suppliers

China 111 Europe 1 Germany 2 India 1 United Kingdom 2 United States 13 Global 130

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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View Lastest Price from 7-Quinolinecarboxylic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 7-Quinolinecarboxylic acid 1078-30-4
Price: US $3.00-9.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 50kg
Release date: 2025-07-28

Zhuozhou Wenxi import and Export Co., Ltd

Product: 7-Quinolinecarboxylic acid 1078-30-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 7-Quinolinecarboxylic acid 1078-30-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

1078-30-4, 7-Quinolinecarboxylic acidRelated Search:

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QUINOLINE-7-CARBOXYLIC ACID

7-QUINOLINECARBOXYLIC ACID

AKOS BBS-00005341

7-Quinolinecarboxylic acid ,98%

7-Carboxyquinoline

quinolin-7-carboxylic acid

7-Carboxyquinoline, 7-Carboxy-1-azanaphthalene

7-Quinolinecarboxylic acid, 95+%

7-QUINOLINEcarboxylic acid 98%

7-Quinolinecarboxylic acid ISO 9001：2015 REACH

1078-30-4

Quinoline Derivertives