ChemicalBook > CAS DataBase List > 7-Quinolinecarboxylic acid

7-Quinolinecarboxylic acid

Product Name
7-Quinolinecarboxylic acid
CAS No.
1078-30-4
Chemical Name
7-Quinolinecarboxylic acid
Synonyms
AKOS BBS-00005341;7-Carboxyquinoline;quinolin-7-carboxylic acid;7-QUINOLINECARBOXYLIC ACID;QUINOLINE-7-CARBOXYLIC ACID;7-QUINOLINEcarboxylic acid 98%;7-Quinolinecarboxylic acid ,98%;7-Quinolinecarboxylic acid, 95+%;7-Quinolinecarboxylic acid ISO 9001：2015 REACH;7-Carboxyquinoline, 7-Carboxy-1-azanaphthalene
CBNumber
CB8782805
Molecular Formula
C10H7NO2
Formula Weight
173.17
MOL File
1078-30-4.mol
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7-Quinolinecarboxylic acid Property

Melting point:
249.5°C
Boiling point:
303.81°C (rough estimate)
Density 
1.2427 (rough estimate)
refractive index 
1.5200 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
solid
pka
2.68±0.30(Predicted)
color 
Off-white
InChI
InChI=1S/C10H7NO2/c12-10(13)8-4-3-7-2-1-5-11-9(7)6-8/h1-6H,(H,12,13)
InChIKey
WXXVQWSDMOAHHV-UHFFFAOYSA-N
SMILES
N1C2C(=CC=C(C(O)=O)C=2)C=CC=1
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Safety

Safety Statements 
24/25
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific
Product number
OR17564
Product name
Quinoline-7-carboxylic acid
Packaging
250mg
Price
$34
Updated
2021/12/16
AK Scientific
Product number
X8858
Product name
7-Quinolinecarboxylicacid
Packaging
250mg
Price
$100
Updated
2021/12/16
Apolloscientific
Product number
OR17564
Product name
Quinoline-7-carboxylic acid
Packaging
1g
Price
$102
Updated
2021/12/16
AK Scientific
Product number
X8858
Product name
7-Quinolinecarboxylicacid
Packaging
1g
Price
$166
Updated
2021/12/16
Matrix Scientific
Product number
073270
Product name
7-Quinolinecarboxylic acid
Purity
95+%
Packaging
1g
Price
$197
Updated
2021/12/16
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7-Quinolinecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Off-white powder

Uses

7-Quinolinecarboxylic acid is a reactant used in the chemical & genetic engineering of selective ion channel-ligand interactions.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 2721, 1946 DOI: 10.1021/ja01216a093

Synthesis

51552-68-2

1078-30-4

Step 1: An aqueous solution (50 mL) of lithium hydroxide monohydrate (5.42 g, 141 mmol, 3.0 equiv) was slowly added to a tetrahydrofuran solution (200 mL) of methyl 7-quinolinecarboxylate (8.8 g, 47 mmol). The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the tetrahydrofuran was removed by distillation under reduced pressure. To the remaining aqueous phase, 1N aqueous hydrochloric acid solution (141 mL) was slowly added and the pH was adjusted to 7, at which time a white precipitate was produced. The precipitate was collected by filtration and washed sequentially with water and heptane. The resulting solid was dried in a vacuum oven at 50 °C to give 7-quinolinecarboxylic acid (8.4 g, 100% yield) as a white solid. Liquid chromatography analysis (detection wavelength 215 nm): retention time 0.66 min, purity 100%. Mass spectrum (electrospray positive ion mode): m/z 174 ([M+H]+). 1H NMR (400 MHz, d6-DMSO): δ 9.02 (1H, dd), 8.58 (1H, s), 8.48 (1H, d), 8.09 (2H, m), 7.66 (1H, dd).

References

[1] Patent: US2007/60567, 2007, A1. Location in patent: Page/Page column 27

7-Quinolinecarboxylic acid Preparation Products And Raw materials

Raw materials

3-Fluoroaniline m-Toluidine Chromium(VI) oxide Glycerol Sodium iodide Ethyl acetate Acetic acid Sodium hydroxide Sulfuric acid

Preparation Products

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7-Quinolinecarboxylic acid Suppliers

China 111 Europe 1 Germany 2 India 1 United Kingdom 2 United States 13 Global 130
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
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View Lastest Price from 7-Quinolinecarboxylic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
7-Quinolinecarboxylic acid 1078-30-4
Price
US $3.00-9.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
50kg
Release date
2025-07-28
Zhuozhou Wenxi import and Export Co., Ltd
Product
7-Quinolinecarboxylic acid 1078-30-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
7-Quinolinecarboxylic acid 1078-30-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

1078-30-4, 7-Quinolinecarboxylic acidRelated Search:

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  • QUINOLINE-7-CARBOXYLIC ACID
  • 7-QUINOLINECARBOXYLIC ACID
  • AKOS BBS-00005341
  • 7-Quinolinecarboxylic acid ,98%
  • 7-Carboxyquinoline
  • quinolin-7-carboxylic acid
  • 7-Carboxyquinoline, 7-Carboxy-1-azanaphthalene
  • 7-Quinolinecarboxylic acid, 95+%
  • 7-QUINOLINEcarboxylic acid 98%
  • 7-Quinolinecarboxylic acid ISO 9001：2015 REACH
  • 1078-30-4
  • Quinoline Derivertives