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Pozelimab

Product Name
Pozelimab
CAS No.
2096328-94-6
Chemical Name
Pozelimab
Synonyms
Pozelimab;Research Grade Pozelimab;Pozelimab (anti-Complement C5);Research Grade Pozelimab (DHB90006)
CBNumber
CB88081128
Formula Weight
0
MOL File
Mol file
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Pozelimab Property

form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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Pozelimab Chemical Properties,Usage,Production

Uses

Pozelimab (REGN3918) is a fully human IgG4 anti-C5 monoclonal antibody. Pozelimab binds to C5 and C5 variants with high affinity and blocks complement-mediated hemolysis. Pozelimab can be used for the research of complement-mediated diseases[1].

in vivo

Pozelimab (15 mg/kg; s.c., once) has a prolonged pharmacokinetic (PK) with a half-life of approximately 13 days in male and female C5hu/hu mice[1].

Animal Model:Cynomolgus monkey[1]
Dosage:15 mg/kg
Administration:Intravenous injection; 15 mg/kg, once
Result:Showed a a greater exposure to monkeys compared with H4H12161P and H4H12170P.

References

[1] Latuszek A, et al. Inhibition of complement pathway activation with Pozelimab, a fully human antibody to complement component C5. PLoS One. 2020 May 8;15(5):e0231892. DOI:10.1371/journal.pone.0231892

Pozelimab Preparation Products And Raw materials

Raw materials

Preparation Products

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Pozelimab Suppliers

China 17 Global 17
Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
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ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994
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QQ:2853530913
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2853530910@QQ.com
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China
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Guangzhou Hongyuan Chemical Co.,Ltd
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15817493340
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981810490@qq.com
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China
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1566
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Wuhan Chemstan Biotechnology Co., Ltd.
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027-65317797 15926423062
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QQ：422450190
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422450190@qq.com
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China
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10308
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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24961
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Biolab Reagents
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027-65279366 18108604356
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products@biolabreagent.com
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China
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Wuhan Jingkangen Biomedical Technology Co., Ltd
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13720134139 086-15871494362 13720134139
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orders@jknbiochem.com
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China
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627
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customer_service@efebio.com
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Changsha Fuzhen Biotechnology Co.，LTD
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0731-13823398 15111215862
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China
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Wanxin Biotechnology (Jiaxing) Co., LTD
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2096328-94-6, PozelimabRelated Search:

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  • Pozelimab
  • Research Grade Pozelimab (DHB90006)
  • Research Grade Pozelimab
  • Pozelimab (anti-Complement C5)
  • 2096328-94-6