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METHYL 4-AMINO-2-FLUOROBENZOATE

Product Name
METHYL 4-AMINO-2-FLUOROBENZOATE
CAS No.
73792-08-2
Chemical Name
METHYL 4-AMINO-2-FLUOROBENZOATE
Synonyms
EnzalutamideImpurity45;Methyl 2-fluoro-4-aminobenzoate;METHYL 4-AMINO-2-FLUOROBENZOATE;Methyl 4-helium-2-fluorobenzoate;2-Fluoro-4-aminobenzoic acid methyl ester;Benzoic acid,4-aMino-2-fluoro-, Methyl ester;4-amino-2-fluoro-Benzoic acid methyl ester (9CI ACI);Benzoic acid, 4-amino-2-fluoro-, methyl ester (9CI, ACI)
CBNumber
CB8840510
Molecular Formula
C8H8FNO2
Formula Weight
169.15
MOL File
73792-08-2.mol
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METHYL 4-AMINO-2-FLUOROBENZOATE Property

Melting point:
Too Dark to Visualize
Boiling point:
302.3±27.0 °C(Predicted)
Density 
1.264±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
1.45±0.10(Predicted)
form 
Solid
color 
Orange to Brown
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M328543
Product name
Methyl4-amino-2-fluorobenzoate
Packaging
1g
Price
$50
Updated
2021/12/16
Apolloscientific
Product number
PC201296
Product name
Methyl4-amino-2-fluorobenzoate
Purity
98%
Packaging
25g
Price
$192
Updated
2021/12/16
ChemScene
Product number
CS-W004728
Product name
Methyl4-amino-2-fluorobenzoate
Packaging
100g
Price
$425
Updated
2021/12/16
Apolloscientific
Product number
PC201296
Product name
Methyl4-amino-2-fluorobenzoate
Purity
98%
Packaging
100g
Price
$575
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0105863
Product name
METHYL 4-AMINO-2-FLUOROBENZOATE
Purity
95.00%
Packaging
1G
Price
$642.18
Updated
2021/12/16
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METHYL 4-AMINO-2-FLUOROBENZOATE Chemical Properties,Usage,Production

Uses

Methyl 4-amino-2-fluorobenzoate is mainly used as an intermediate in organic synthesis, especially in the field of pharmaceutical manufacturing.

Synthesis

392-09-6

73792-08-2

Step 2: Methyl 2-fluoro-4-nitrobenzoate (1.05 g, 5.273 mmol) was dissolved in methanol (MeOH). Palladium/carbon (Pd/C, 105 mg) was added to the resulting solution. The reaction mixture was stirred for 2 hours at room temperature in a hydrogen (H2) atmosphere. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad to remove the catalyst. The filtrate was concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography to give the final pure methyl 4-amino-2-fluorobenzoate (870 mg, 98% yield).

References

[1] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 19, p. 7042 - 7051
[2] Patent: WO2013/68467, 2013, A1. Location in patent: Page/Page column 57; 59; 60; 61
[3] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 2, p. 337 - 343
[4] Patent: WO2004/14900, 2004, A1. Location in patent: Page 52
[5] Journal of Organic Chemistry, 1990, vol. 55, # 7, p. 2034 - 2044

METHYL 4-AMINO-2-FLUOROBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 4-AMINO-2-FLUOROBENZOATE Suppliers

Canada 1 China 128 India 2 United States 8 Global 139
Yangzhou Siyu Chemical Co.,Ltd.
Tel
0514-87325867
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0086-514-87325867
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sales@siyuchem.com
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China
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370
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55
Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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sales8178@energy-chemical.com
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China
ProdList
44801
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61
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
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2355560935@qq.com
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China
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12000
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Adamas Reagent, Ltd.
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400-6009262 16621234537
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021-64823266
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chenyj@titansci.com
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China
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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+86-25-83453306
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info@chemlin.com.cn
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China
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64
Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
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China
ProdList
42934
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64
Shanghai Sunway Pharmaceutical Technology Co., Ltd
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18270980682
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021 51613951
Email
mlcheng@sunwaypharm.cn
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China
ProdList
8669
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Wuhan ariel chemical Co., LTD.
Tel
18986259541
Fax
027-87840182
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sales@3stc.com
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China
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3764
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Tianjin Jinyuda Chemical Co., Ltd.
Tel
022-58013646 13011382049
Fax
022-23854368
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sales@jinyudachem.com
Country
China
ProdList
1930
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55
T&W GROUP
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021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
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China
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9895
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View Lastest Price from METHYL 4-AMINO-2-FLUOROBENZOATE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
METHYL 4-AMINO-2-FLUOROBENZOATE 73792-08-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2025-03-10
Shaanxi Dideu Medichem Co. Ltd
Product
Methyl 4-aMino-2-fluorobenzoate 73792-08-2
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-07
Henan Bao Enluo International TradeCo.，LTD
Product
METHYL 4-AMINO-2-FLUOROBENZOATE 73792-08-2
Price
US $50.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
10000MT
Release date
2023-08-15

73792-08-2, METHYL 4-AMINO-2-FLUOROBENZOATERelated Search:

4-Bromo-2-fluoro-N-methylbenzamide 4-BROMO-2-FLUOROBENZAMIDE 4-amino-2-fluoro-N-methylbenzamide 4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- Enzalutamide Impurity 7 Benzoic acid, 4-isothiocyanato-2-(trifluoromethyl)- 2-FLUORO-N-METHYL-4-NITROBENZAMIDE 2-Fluoro-4-nitrobenzoic acid 4-Amino-2-(trifluoromethyl)benzamide 4-NITRO-2-(TRIFLUOROMETHYL)BENZONITRILE 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile 4-AMINO-2-FLUOROBENZOIC ACID Enzalutamide Impurity 1 Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-5,5-dimethyl-4-oxo-1-imidazolidinyl]-2-fluoro-N-methyl- Benzamide, 4-amino-2-fluoro- (9CI) 4-Amino-2-fluoro-N,N-dimethylbenzamide 4-AMINO-2-TRIFLUOROMETHYLBENZOIC ACID Enzalutamide Impurity 7

  • METHYL 4-AMINO-2-FLUOROBENZOATE
  • 2-Fluoro-4-aminobenzoic acid methyl ester
  • Methyl 2-fluoro-4-aminobenzoate
  • Benzoic acid,4-aMino-2-fluoro-, Methyl ester
  • EnzalutamideImpurity45
  • Benzoic acid, 4-amino-2-fluoro-, methyl ester (9CI, ACI)
  • 4-amino-2-fluoro-Benzoic acid methyl ester (9CI ACI)
  • Methyl 4-helium-2-fluorobenzoate
  • 73792-08-2