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Urocortin II (mouse)

Product Name
Urocortin II (mouse)
CAS No.
330648-32-3
Chemical Name
Urocortin II (mouse)
Synonyms
UROCORTIN II (MOUSE);UCN II (MOUSE) TRIFLUOROACETATE;UROCORTIN II (MOUSE) TRIFLUOROACETATE;H-VAL-ILE-LEU-SER-LEU-ASP-VAL-PRO-ILE-GLY-LEU-LEU-ARG-ILE-LEU-LEU-GLU-GLN-ALA-ARG-TYR-LYS-ALA-ALA-ARG-ASN-GLN-ALA-ALA-THR-ASN-ALA-GLN-ILE-LEU-ALA-HIS-VAL-NH2 TRIFLUOROACETATE
CBNumber
CB8847807
Formula Weight
0
MOL File
Mol file
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Urocortin II (mouse) Property

storage temp. 
-20°C
form 
Solid
color 
White to off-white
biological source
mouse
Sequence
Val-Ile-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Arg-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Tyr-Lys-Ala-Ala-Arg-Asn-Gln-Ala-Ala-Thr-Asn-Ala-Gln-Ile-Leu-Ala-His-Val-NH2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
U9507
Product name
Urocortin II mouse
Packaging
500 μg
Price
$442
Updated
2025/07/31
Sigma-Aldrich
Product number
U9507
Product name
Urocortin II mouse
Packaging
500μg
Price
$257.4
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
PEP0010194
Product name
H-VAL-ILE-LEU-SER-LEU-ASP-VAL-PRO-ILE-GLY-LEU-LEU-ARG-ILE-LEU-LEU-GLU-GLN-ALA-ARG-TYR-LYS-ALA-ALA-ARG-ASN-GLN-ALA-ALA-THR-ASN-ALA-GLN-ILE-LEU-ALA-HIS-VAL-NH2 TRIFLUOROACETATE
Purity
95.00%
Packaging
5MG
Price
$500.53
Updated
2021/12/16
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Urocortin II (mouse) Chemical Properties,Usage,Production

Uses

Mouse urocortin II can be used for immunohistochemistry.

Biochem/physiol Actions

Urocortin II is a CRF-related neuropeptide having high affinity for CRF2 receptor. It stimulates protein kinase A through CRF2 receptor and increases the contractility in rabbit ventricular myocytes. It also facilitates pro-inflammatory effects in human intestinal cells through corticotropin-releasing hormone receptor 2α.

in vivo

Urocortin II, mouse (1-10 μg; icv and i.v.; Adult male Sprague-Dawley rats) induces the expression of Fos[2].
Urocortin II, mouse (1 μg; icv; Adult male Sprague-Dawley rats) is involved in central autonomic nervous system and appetite control[2].

Animal Model:Adult male Sprague-Dawley rats (250-300 g)[2]
Dosage:1, 5, and 10 μg
Administration:Intracerebroventrical injection and intravenous injection; 1, 5, or 10 μg per animal in 2 μL of saline for i.c.v. injections or 200 μL for i.v. administration
Result:Induced Fos expression in a dose-dependent manner.
Animal Model:Adult male Sprague-Dawley rats (250-300 g)[2]
Dosage:1 μg
Administration:Intracerebroventrical injection
Result:Reduced food intake over the 12-h interval.

IC 50

CRFR2: 0.66 nM (Ki); CRFR1: ﹥100 nM (Ki)

Urocortin II (mouse) Preparation Products And Raw materials

Raw materials

Preparation Products

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