FALECALCITRIOL
- Product Name
- FALECALCITRIOL
- CAS No.
- 83805-11-2
- Chemical Name
- FALECALCITRIOL
- Synonyms
- Hornel;ST 630;Fulstan;Ro 23-4194;Flocalcitrol;Flocacitriol;Falecalcitol;Flocalcitriol;F6-1,25(OH)2D3;FALECALCITRIOL
- CBNumber
- CB8849801
- Molecular Formula
- C27H38F6O3
- Formula Weight
- 524.58
- MOL File
- 83805-11-2.mol
FALECALCITRIOL Property
- Boiling point:
- 576.9±50.0 °C(Predicted)
- Density
- 1.24±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C,unstable in solution, ready to use.
- solubility
- Soluble in DMSO
- form
- Powder
- pka
- 9.77±0.29(Predicted)
N-Bromosuccinimide Price
- Product number
- F101110
- Product name
- Falecalcitriol
- Packaging
- 10mg
- Price
- $11000
- Updated
- 2021/12/16
- Product number
- API0002674
- Product name
- FALECALCITRIOL
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $12127.5
- Updated
- 2021/12/16
- Product number
- CS-0801
- Product name
- Falecalcitriol
- Purity
- 95.09%
- Packaging
- 1mg
- Price
- $1056
- Updated
- 2021/12/16
- Product number
- API0002674
- Product name
- FALECALCITRIOL
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $1424.85
- Updated
- 2021/12/16
- Product number
- 17932
- Product name
- Falecalcitriol
- Packaging
- 1mg
- Price
- $1790
- Updated
- 2021/12/16
FALECALCITRIOL Chemical Properties,Usage,Production
Description
Falecalcitriol, previously known as flocalcitrol, was launched by several codevelopers in Japan for the treatment of secondary hyperthyroidism (SHPT). This hexafluorinated analog of 1α,25-dihydroxyvitamin D3 (calcitriol), the hormonally active form of vitamin D3, can be obtained by several different synthetic routes from a conveniently protected cholestenol, a key step being an aldol reaction with hexafluoroacetone. Falecalcitriol is several times more active than 1,25(OH)2D3 in regulating the proliferation of parathyroid cells and parathyroid hormone (PTH) synthesis that are believed to be mediated through binding to VDR, a nuclear receptor for vitamin D; furthermore, it was proposed that a bioactive 23S-hydroxylated metabolite, resistant to further metabolism, contributes to the retention of an active compound for longer in cells and so, to significantly lengthen the duration of action. In a comparative clinical study conducted in hemodialysis patients with moderate to severe SHPT, falecalcitriol was found to be more active than alfacalcidol in suppressing parathyroid hormone without triggering hypercalcemia.
Originator
University of Wisconsin (US)
Uses
Hexafluorinated analog of Calcitriol (C144500). A more potent therapeutic agent for secondary hyperparathyroidism.
brand name
Hornel, Fulstan
Hazard
A poison by ingestion.
FALECALCITRIOL Preparation Products And Raw materials
Raw materials
Preparation Products
FALECALCITRIOL Suppliers
- Tel
- 13287715206
- 2786175817@qq.com
- Country
- China
- ProdList
- 45
- Advantage
- 58
- Tel
- 027-83778876 13667159345
- Fax
- 027-83778876
- 13667159345@163.com
- Country
- China
- ProdList
- 1942
- Advantage
- 55
- Tel
- 021-50790412
- Fax
- +86-21-50790419
- info@chemvon.com
- Country
- China
- ProdList
- 371
- Advantage
- 57
- Tel
- 021-20908456
- Fax
- 021-58180499
- sales@BioChemBest.com
- Country
- China
- ProdList
- 6011
- Advantage
- 61
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 15421
- Advantage
- 60
- Tel
- 021-58950125
- Fax
- (86) 21-58955996
- info@chemexpress.com
- Country
- China
- ProdList
- 7553
- Advantage
- 61
- Tel
- 0755-0755-66853366 13670046396
- Fax
- 0755-28363542
- sales@chem-strong.com
- Country
- China
- ProdList
- 17994
- Advantage
- 56
- Tel
- 15981924004; 19943855286
- Fax
- 0371-53392065
- Trizpharm@aliyun.com
- Country
- China
- ProdList
- 1875
- Advantage
- 56
- Tel
- 021-50215258
- Fax
- 021-50215756
- market@hypharma.com
- Country
- China
- ProdList
- 321
- Advantage
- 58
- Tel
- 0943-6900332 17789447501
- Fax
- 0931-8238232
- zhuanxiajiang@haotianpharm.com
- Country
- China
- ProdList
- 208
- Advantage
- 55
- Tel
- 86(21)68097365
- Fax
- 86(21)33321566
- sales@anpharma.net
- Country
- China
- ProdList
- 4901
- Advantage
- 55
- Tel
- +86-400-851-9921
- Fax
- +86-10-82826195
- sales@pharmacodia.com
- Country
- China
- ProdList
- 2317
- Advantage
- 55
- Tel
- 020-61288194 61288195
- Fax
- 020-61288700
- 505721671@qq.com
- Country
- China
- ProdList
- 3868
- Advantage
- 58
- Tel
- 400-1166-196 18502815961
- Fax
- QQ:800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 14623
- Advantage
- 60
- Tel
- 17836913271
- Fax
- 0374-8348899
- 3224305243@qq.com
- Country
- China
- ProdList
- 2718
- Advantage
- 58
- Tel
- 027-027-83778875 15807197853
- Fax
- 027-83991220
- 15807197853@163.com
- Country
- China
- ProdList
- 3977
- Advantage
- 58
- Tel
- 571-85586718 +8613336195806
- Fax
- +86-571-85864795
- sales@capotchem.com
- Country
- China
- ProdList
- 29797
- Advantage
- 60
- Tel
- 025-66113011 18112977050
- Fax
- 02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 16028
- Advantage
- 58
- Tel
- 027-87466105 15377573527
- 2678564200@qq.com
- Country
- China
- ProdList
- 17997
- Advantage
- 58
- Tel
- +86-0371-55023472 +86-13663848272
- Fax
- 0371-55023472
- 2584787837@qq.com
- Country
- China
- ProdList
- 166
- Advantage
- 58
- Tel
- 400-400-400-9004166 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52712
- Advantage
- 58
- Tel
- +8619313119731 19186994443
- sales@chemfish.com
- Country
- China
- ProdList
- 4917
- Advantage
- 58
- Tel
- +86-400-002-6226 13028896684
- sales@rrkchem.com
- Country
- China
- ProdList
- 55896
- Advantage
- 58
- Tel
- 0576-88813233 13396860566
- sales@pharm-intermediates.com
- Country
- China
- ProdList
- 2013
- Advantage
- 58
- Tel
- 0551-65418684 +8618949823763
- Fax
- 0086-551-65418684
- sales@tnjchem.com
- Country
- China
- ProdList
- 25363
- Advantage
- 58
- Tel
- fred.wen@crcorporation.cn
- Country
- CHINA
- ProdList
- 12069
- Advantage
- 58
- Tel
- 571-88938639 +8617705817739
- Fax
- +86-571-88938652,+86-571- 88492614
- info@dycnchem.com
- Country
- CHINA
- ProdList
- 52867
- Advantage
- 58
- Tel
- +8617735180244
- mike_yan@xuanranglobal.com
- Country
- CHINA
- ProdList
- 4022
- Advantage
- 58
- Tel
- 17825480238
- Fax
- QQ 3008233717
- 3008233717@qq.com
- Country
- China
- ProdList
- 9843
- Advantage
- 12
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- chemwill_asia@126.com
- Country
- CHINA
- ProdList
- 23931
- Advantage
- 58
- Tel
- 021-58447131 13564518121
- sales@dcchemicals.com
- Country
- China
- ProdList
- 9414
- Advantage
- 58
- Tel
- 2710913286@.com
- 1513643261@qq.com
- Country
- China
- ProdList
- 14253
- Advantage
- 58
- Tel
- 021-58950125
- Fax
- 021-58955996
- info@chemexpress.com
- Country
- China
- ProdList
- 695
- Advantage
- 58
- Tel
- 021-13773155751 19901447308
- 260924549@qq.com
- Country
- China
- ProdList
- 8675
- Advantage
- 58
- Tel
- 18818260767
- Fax
- QQ 3610331285
- sales@chemegen.com
- Country
- China
- ProdList
- 11289
- Advantage
- 58
- Tel
- +8618523575427
- sales@conier.com
- Country
- China
- ProdList
- 49391
- Advantage
- 58
- Tel
- +86-0371-86658258 15093356674;
- Fax
- 0086-371-86658258
- factory@coreychem.com
- Country
- China
- ProdList
- 29826
- Advantage
- 58
- Tel
- 029-61856359 18690052321
- Fax
- 029-88380327
- 1027@dideu.com
- Country
- China
- ProdList
- 10011
- Advantage
- 58
- Tel
- 4008210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 55023
- Advantage
- 58
- Tel
- 027-027-52344656 15871722230
- Fax
- 2796190295
- 15871722230@163.com
- Country
- China
- ProdList
- 3000
- Advantage
- 58
- Tel
- 15623309010
- 1287744812@qq.com
- Country
- China
- ProdList
- 1657
- Advantage
- 58
- Tel
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29778
- Advantage
- 58
- Tel
- 0757-85921206 18520245316
- 2329783215@qq.com
- Country
- China
- ProdList
- 12664
- Advantage
- 58
- Tel
- 13184580281
- Fax
- 400-880-2824
- hj@ruiweier.cn
- Country
- China
- ProdList
- 2102
- Advantage
- 58
- Tel
- 13989459766
- 348632238@qq.com
- Country
- China
- ProdList
- 178
- Advantage
- 58
- Tel
- 027-59101668 19945030958
- Fax
- 027-59101668
- 2881924765@qq.com
- Country
- China
- ProdList
- 7977
- Advantage
- 58
- Tel
- 15071299552
- Fax
- QQ:262933239
- 262933239@qq.com
- Country
- China
- ProdList
- 6637
- Advantage
- 58
- Tel
- 185-0276-2003 18502762003;
- 435918333@qq.com
- Country
- China
- ProdList
- 2243
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24024
- Advantage
- 58
- Tel
- 15252131412
- 5954981@qq.com
- Country
- China
- ProdList
- 3039
- Advantage
- 58
View Lastest Price from FALECALCITRIOL manufacturers
- Product
- FALECALCITRIOL 83805-11-2
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-02-18