ChemicalBook > CAS DataBase List > N-Methyl-4-piperidinol

N-Methyl-4-piperidinol

Product Name
N-Methyl-4-piperidinol
CAS No.
106-52-5
Chemical Name
N-Methyl-4-piperidinol
Synonyms
1-methylpiperidin-4-ol;1-METHYL-4-PIPERIDINOL;4-Piperidinol, 1-methyl-;H431;NM4PPOL;-4-piperidinoL;N-Methylpiperidol;N-Methyl-4-hydroxy;TIMTEC-BB SBB004301;1-methyl-4-piperidino
CBNumber
CB8852683
Molecular Formula
C6H13NO
Formula Weight
115.17
MOL File
106-52-5.mol
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N-Methyl-4-piperidinol Property

Melting point:
29-31 °C(lit.)
Boiling point:
200 °C(lit.)
Density 
0.98 g/mL at 20 °C(lit.)
vapor pressure 
8.13-11Pa at 25℃
refractive index 
n20/D 1.479
Flash point:
190 °F
storage temp. 
2-8°C
form 
Liquid After Melting
pka
14.87±0.20(Predicted)
color 
Clear colorless to brown
Water Solubility 
MISCIBLE
Sensitive 
Hygroscopic
BRN 
103024
LogP
-0.14-0.756 at 25℃
CAS DataBase Reference
106-52-5(CAS DataBase Reference)
NIST Chemistry Reference
4-Hydroxy-N-methylpiperidine(106-52-5)
EPA Substance Registry System
4-Piperidinol, 1-methyl- (106-52-5)
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Safety

Hazard Codes 
Xi,C
Risk Statements 
37/38-41-36/37/38-34
Safety Statements 
26-37/39-45-36/37/39-27
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H42206
Product name
N-Methyl-4-piperidinol
Purity
98%
Packaging
100g
Price
$89.5
Updated
2024/03/01
TCI Chemical
Product number
M0933
Product name
4-Hydroxy-1-methylpiperidine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
M0933
Product name
4-Hydroxy-1-methylpiperidine
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$223
Updated
2024/03/01
Alfa Aesar
Product number
L06415
Product name
4-Hydroxy-1-methylpiperidine, 98%
Packaging
100g
Price
$44.65
Updated
2024/03/01
Alfa Aesar
Product number
L06415
Product name
4-Hydroxy-1-methylpiperidine, 98%
Packaging
500g
Price
$149.65
Updated
2024/03/01
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N-Methyl-4-piperidinol Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellowish liquid after melting

Uses

Reactant for:• ;Optimization of Novobiocin scaffold to product antitumor agents1• ;Substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis2Reactant for synthesis of:• ;CaMKII inhibitors3• ;VEGFR and FGFR kinase inhibitors4• ;Phosphoinositide-3-kinase inhibitors5• ;Protein lysine methyltransferase G9a inhibitors6

Uses

4-Hydroxy-1-methylpiperidine is used as reactant for optimization of Novobiocin scaffold to product antitumor agents, substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis. It is also used as a reactant in the synthesis of CaMKII, VEGFR and FGFR kinase inhibitors and Phosphoinositide-3-kinase, Protein lysine methyltransferase G9a inhibitors.

Flammability and Explosibility

Not classified

N-Methyl-4-piperidinol Preparation Products And Raw materials

Raw materials

1-Methyl-4-piperidone

Preparation Products

4-(1-METHYLPIPERIDIN-4-YLOXY)-3,5-DICHLOROBENZENAMINE
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View Lastest Price from N-Methyl-4-piperidinol manufacturers

Anhui Dexinjia Biopharm Co., Ltd
Product
1-Methyl-4-Hydroxypiperidine 106-52-5
Price
US $100.00-2000.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
5MT per Month
Release date
2021-01-15
Shaanxi Dideu Medichem Co. Ltd
Product
N-Methyl-4-piperidinol 106-52-5
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2024-08-05
Anhui Ruihan Technology Co., Ltd
Product
1-Methyl-4-piperidinol 106-52-5
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000t/year
Release date
2023-09-21

106-52-5, N-Methyl-4-piperidinol Related Search:

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