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Octanoyl chloride

Product Name
Octanoyl chloride
CAS No.
111-64-8
Chemical Name
Octanoyl chloride
Synonyms
OctanoyL;Octanoyl chlorid;CAPRYLYL CHLORIDE;N-OCTANOYL CHLORIDE;OCTANOIC ACID CHLORIDE;OTCL;Xin chloride;Caprylyl chlorid;octanoicchloride;n-Caprylchloride
CBNumber
CB8852845
Molecular Formula
C8H15ClO
Formula Weight
162.66
MOL File
111-64-8.mol
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Octanoyl chloride Property

Melting point:
-63 °C
Boiling point:
195 °C (lit.)
Density 
0.953 g/mL at 25 °C (lit.)
vapor pressure 
2.5 mm Hg ( 20 °C)
refractive index 
n20/D 1.435(lit.)
Flash point:
177 °F
storage temp. 
−20°C
solubility 
soluble in Chloroform, Methanol
form 
Liquid
color 
Clear
Odor
pungent odor
Water Solubility 
REACTS
Sensitive 
Moisture Sensitive
BRN 
635917
Stability:
Moisture sensitive
CAS DataBase Reference
111-64-8(CAS DataBase Reference)
NIST Chemistry Reference
Octanoyl chloride(111-64-8)
EPA Substance Registry System
Octanoyl chloride (111-64-8)
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Safety

Hazard Codes 
C,T
Risk Statements 
34-22-43-41-38-23
Safety Statements 
26-36/37/39-45-25-39-37-24
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
RTECS 
RH1570000
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29159080
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H330Fatal if inhaled

Precautionary statements

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
O4733
Product name
Octanoyl chloride
Purity
99%
Packaging
5ml
Price
$49.8
Updated
2024/03/01
Sigma-Aldrich
Product number
O4733
Product name
Octanoyl chloride
Purity
99%
Packaging
100ml
Price
$53.4
Updated
2024/03/01
TCI Chemical
Product number
O0039
Product name
n-Octanoyl Chloride
Purity
>99.0%(GC)
Packaging
25mL
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
O0039
Product name
n-Octanoyl Chloride
Purity
>99.0%(GC)
Packaging
100mL
Price
$42
Updated
2024/03/01
Alfa Aesar
Product number
L03526
Product name
Octanoyl chloride, 99%
Packaging
100ml
Price
$31.4
Updated
2024/03/01
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Octanoyl chloride Chemical Properties,Usage,Production

Chemical Properties

clear liquid

Uses

Octanoyl chloride is used to produce adhesives. It is used as an acylating agent for a variety of compounds such as sugars (e.g. Sucrose, aromatic compounds (e.g. Anisole and monoglycerides.

Uses

Applications of octanoyl chloride include:

  • Synthesis of (R)-2-propyloctanoic acid, a therapeutic agent for Alzheimer′s disease.
  • Synthesis of a variety of N-n-octyl-D-gluconamide based organogels.
  • Building 2-heptylbenzo[d]thiazole moiety to synthesize conjugated copolymer with fluorine, as cathode interlayer in inverted polymer solar cells (PSCs).
  • Octanoyl chloride is one of the essential precursors in the total synthesis of (?)-mandelalide L, a marine macrolide that display significant cytotoxicity against human cancer cell lines.

Preparation

Diphosgene (108.8 g) was added to a mixture of octanoic acid (144.2 g) and DMF (1.5 L) at 70 C°. The mixture was left to stand for 1 h, and then nitrogen was bubbled through it for 30 min at 100 C° to give 96.9% of octanoyl chloride (purity 99.99%). Benzoyl chloride and terephthaloyl chloride were similarly prepared.

General Description

Clear colorless to straw-colored liquid with a pungent odor.

Air & Water Reactions

Reacts vigorously with water to form HCl and caprylic acid. Insoluble in water.

Reactivity Profile

Octanoyl chloride is incompatible with bases (including amines), water, alcohols, and with oxidizing agents . May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Fire Hazard

Octanoyl chloride is combustible.

Octanoyl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Octanoyl chloride Suppliers

Portail Substances Chimiques
Tel
--
Fax
--
Email
webmestre-substances@ineris.fr
Country
France
ProdList
6024
Advantage
58
ISOCHEM
Tel
--
Fax
--
Email
x.jeanjean@snpe.com
Country
France
ProdList
221
Advantage
54
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View Lastest Price from Octanoyl chloride manufacturers

Anhui Royal Chemical Co., Ltd.
Product
Octanoyl chloride 111-64-8
Price
US $1.00/KG
Min. Order
25KG
Purity
99%
Supply Ability
2tons
Release date
2018-08-08
Hebei Yanxi Chemical Co., Ltd.
Product
Octanoyl chloride 111-64-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99.00%
Supply Ability
20tons
Release date
2023-09-12
Hebei Chuanghai Biotechnology Co,.LTD
Product
Octanoyl chloride 111-64-8
Price
US $15.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-08-16

111-64-8, Octanoyl chlorideRelated Search:


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