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N-Methyl-D-aspartic acid

Product Name
N-Methyl-D-aspartic acid
CAS No.
6384-92-5
Chemical Name
N-Methyl-D-aspartic acid
Synonyms
NMDA;n-methylaspartate;N-Me-D-Asp;H-D-MEASP-OH;N-ME-D-ASP-OH;H-D-MEASP-OH HCL;-D-aspartic acid;N-ME-D-ASP-OH HCL;N-Methyl-D-Asp-OH;N-ME-D-ASPARTIC ACID
CBNumber
CB8854056
Molecular Formula
C5H9NO4
Formula Weight
147.13
MOL File
6384-92-5.mol
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N-Methyl-D-aspartic acid Property

Melting point:
187-192 °C
alpha 
-28 º (c=1, HCl 6N)
Boiling point:
267.21°C (rough estimate)
Density 
1.4285 (rough estimate)
refractive index 
-15 ° (C=2, H2O)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly)
pka
2.21±0.23(Predicted)
form 
solid
color 
white
Water Solubility 
slightly soluble
Sensitive 
Hygroscopic
Merck 
14,6662
BRN 
1724431
LogP
1.390 (est)
CAS DataBase Reference
6384-92-5(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
CI9457000
10
HS Code 
29225090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H319Causes serious eye irritation

H372Causes damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M3262
Product name
N-Methyl-D-aspartic acid
Purity
≥98% (TLC), solid
Packaging
1g
Price
$1040
Updated
2024/03/01
Sigma-Aldrich
Product number
454575
Product name
N-Methyl-D-aspartic Acid, Hydrate
Purity
Excitatory amino acid neurotransmitter.
Packaging
100mg
Price
$322
Updated
2024/03/01
TCI Chemical
Product number
M1360
Product name
N-Methyl-D-aspartic Acid
Purity
>98.0%(T)
Packaging
100mg
Price
$22
Updated
2024/03/01
TCI Chemical
Product number
M1360
Product name
N-Methyl-D-aspartic Acid
Purity
>98.0%(T)
Packaging
1g
Price
$56
Updated
2024/03/01
Alfa Aesar
Product number
J61361
Product name
N-Methyl-D-aspartic acid, 98+%
Packaging
50mg
Price
$75.65
Updated
2024/03/01
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N-Methyl-D-aspartic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

NMDA agonist

Uses

NMDA(N-Methyl-D-aspartic acid)is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.

Definition

ChEBI: An aspartic acid derivative having an N-methyl substituent and D-configuration.

General Description

N-Methyl-D-aspartic acid (NMDA) is an endogenously generated molecule in rat nervous system and endocrine glands. NMDA is present at low level (nmol/g) in the adenohypophysis, hypothalamus, brain, and testis. NMDA is derived from D-Asp by an S-adenosylmethionine-dependent enzyme also referred to as NMDA synthase.

Biological Activity

Prototypic NMDA receptor agonist. Also available as part of the Mixed NMDA Receptor Tocriset™ .

Biochem/physiol Actions

Excitotoxic amino acid. Prototypic agonist at the NMDA-type glutamate receptor that regulates ion channels; important in long-term potentiation, ischemia, and epilepsy.

storage

Room temperature

References

[1] watkins jc, jane de. the glutamate story. br j pharmacol. 2006 jan;147 suppl 1:s100-8.
[2] lafon-cazal m, pietri s, culcasi m, bockaert j. nmda-dependent superoxide production and neurotoxicity. nature. 1993 aug 5;364(6437):535-7.

N-Methyl-D-aspartic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Methyl-D-aspartic acid Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
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View Lastest Price from N-Methyl-D-aspartic acid manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
N-Me-D-Asp 6384-92-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-04-13
Hebei Weibang Biotechnology Co., Ltd
Product
N-Methyl-D-aspartic acid ( NMDA ) 99% 6384-92-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-04
Hebei Dangtong Import and export Co LTD
Product
N-Methyl-D-aspartic acid 6384-92-5
Price
US $3288.00-2680.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-09-15

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  • Modified Amino Acids
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  • Glutamate
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