N-Methyl-D-aspartic acid
- Product Name
- N-Methyl-D-aspartic acid
- CAS No.
- 6384-92-5
- Chemical Name
- N-Methyl-D-aspartic acid
- Synonyms
- NMDA;n-methylaspartate;N-Me-D-Asp;H-D-MEASP-OH;N-ME-D-ASP-OH;H-D-MEASP-OH HCL;-D-aspartic acid;N-ME-D-ASP-OH HCL;N-Methyl-D-Asp-OH;N-ME-D-ASPARTIC ACID
- CBNumber
- CB8854056
- Molecular Formula
- C5H9NO4
- Formula Weight
- 147.13
- MOL File
- 6384-92-5.mol
N-Methyl-D-aspartic acid Property
- Melting point:
- 187-192 °C
- alpha
- -28 º (c=1, HCl 6N)
- Boiling point:
- 267.21°C (rough estimate)
- Density
- 1.4285 (rough estimate)
- refractive index
- -15 ° (C=2, H2O)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly)
- pka
- 2.21±0.23(Predicted)
- form
- solid
- color
- white
- Water Solubility
- slightly soluble
- Sensitive
- Hygroscopic
- Merck
- 14,6662
- BRN
- 1724431
- LogP
- 1.390 (est)
- CAS DataBase Reference
- 6384-92-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H319Causes serious eye irritation
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
- Precautionary statements
-
P273Avoid release to the environment.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M3262
- Product name
- N-Methyl-D-aspartic acid
- Purity
- ≥98% (TLC), solid
- Packaging
- 1g
- Price
- $1040
- Updated
- 2024/03/01
- Product number
- 454575
- Product name
- N-Methyl-D-aspartic Acid, Hydrate
- Purity
- Excitatory amino acid neurotransmitter.
- Packaging
- 100mg
- Price
- $322
- Updated
- 2024/03/01
- Product number
- M1360
- Product name
- N-Methyl-D-aspartic Acid
- Purity
- >98.0%(T)
- Packaging
- 100mg
- Price
- $22
- Updated
- 2024/03/01
- Product number
- M1360
- Product name
- N-Methyl-D-aspartic Acid
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $56
- Updated
- 2024/03/01
- Product number
- J61361
- Product name
- N-Methyl-D-aspartic acid, 98+%
- Packaging
- 50mg
- Price
- $75.65
- Updated
- 2024/03/01
N-Methyl-D-aspartic acid Chemical Properties,Usage,Production
Chemical Properties
white to off-white crystalline powder
Uses
NMDA agonist
Uses
NMDA（N-Methyl-D-aspartic acid）is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.
Definition
ChEBI: An aspartic acid derivative having an N-methyl substituent and D-configuration.
General Description
N-Methyl-D-aspartic acid (NMDA) is an endogenously generated molecule in rat nervous system and endocrine glands. NMDA is present at low level (nmol/g) in the adenohypophysis, hypothalamus, brain, and testis. NMDA is derived from D-Asp by an S-adenosylmethionine-dependent enzyme also referred to as NMDA synthase.
Biological Activity
Prototypic NMDA receptor agonist. Also available as part of the Mixed NMDA Receptor Tocriset™ .
Biochem/physiol Actions
Excitotoxic amino acid. Prototypic agonist at the NMDA-type glutamate receptor that regulates ion channels; important in long-term potentiation, ischemia, and epilepsy.
storage
Room temperature
References
[1] watkins jc, jane de. the glutamate story. br j pharmacol. 2006 jan;147 suppl 1:s100-8.
[2] lafon-cazal m, pietri s, culcasi m, bockaert j. nmda-dependent superoxide production and neurotoxicity. nature. 1993 aug 5;364(6437):535-7.
N-Methyl-D-aspartic acid Preparation Products And Raw materials
Raw materials
Preparation Products
N-Methyl-D-aspartic acid Suppliers
View Lastest Price from N-Methyl-D-aspartic acid manufacturers
- Product
- N-Methyl-D-aspartic acid 6384-92-5
- Price
- US $3288.00-2680.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2023-09-15
- Product
- N-Me-D-Asp 6384-92-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-04-13
- Product
- N-Methyl-D-aspartic acid 6384-92-5
- Price
- US $1.00-9.90/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2023-04-11