ChemicalBook > CAS DataBase List > N-Methyl-D-aspartic acid

N-Methyl-D-aspartic acid

Product Name
N-Methyl-D-aspartic acid
CAS No.
6384-92-5
Chemical Name
N-Methyl-D-aspartic acid
Synonyms
NMDA;n-methylaspartate;N-Me-D-Asp;H-D-MEASP-OH;N-ME-D-ASP-OH;H-D-MEASP-OH HCL;-D-aspartic acid;N-ME-D-ASP-OH HCL;N-Methyl-D-Asp-OH;N-ME-D-ASPARTIC ACID
CBNumber
CB8854056
Molecular Formula
C5H9NO4
Formula Weight
147.13
MOL File
6384-92-5.mol
More
Less

N-Methyl-D-aspartic acid Property

Melting point:
187-192 °C
alpha 
-28 º (c=1, HCl 6N)
Boiling point:
267.21°C (rough estimate)
Density 
1.4285 (rough estimate)
refractive index 
-15 ° (C=2, H2O)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly)
pka
2.21±0.23(Predicted)
form 
solid
color 
white
Water Solubility 
slightly soluble
Sensitive 
Hygroscopic
Merck 
14,6662
BRN 
1724431
LogP
1.390 (est)
CAS DataBase Reference
6384-92-5(CAS DataBase Reference)
More
Less

Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
CI9457000
10
HS Code 
29225090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H319Causes serious eye irritation

H372Causes damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M3262
Product name
N-Methyl-D-aspartic acid
Purity
≥98% (TLC), solid
Packaging
1g
Price
$1040
Updated
2024/03/01
Sigma-Aldrich
Product number
454575
Product name
N-Methyl-D-aspartic Acid, Hydrate
Purity
Excitatory amino acid neurotransmitter.
Packaging
100mg
Price
$322
Updated
2024/03/01
TCI Chemical
Product number
M1360
Product name
N-Methyl-D-aspartic Acid
Purity
>98.0%(T)
Packaging
100mg
Price
$22
Updated
2024/03/01
TCI Chemical
Product number
M1360
Product name
N-Methyl-D-aspartic Acid
Purity
>98.0%(T)
Packaging
1g
Price
$56
Updated
2024/03/01
Alfa Aesar
Product number
J61361
Product name
N-Methyl-D-aspartic acid, 98+%
Packaging
50mg
Price
$75.65
Updated
2024/03/01
More
Less

N-Methyl-D-aspartic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

NMDA agonist

Uses

NMDA(N-Methyl-D-aspartic acid)is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.

Definition

ChEBI: An aspartic acid derivative having an N-methyl substituent and D-configuration.

General Description

N-Methyl-D-aspartic acid (NMDA) is an endogenously generated molecule in rat nervous system and endocrine glands. NMDA is present at low level (nmol/g) in the adenohypophysis, hypothalamus, brain, and testis. NMDA is derived from D-Asp by an S-adenosylmethionine-dependent enzyme also referred to as NMDA synthase.

Biological Activity

Prototypic NMDA receptor agonist. Also available as part of the Mixed NMDA Receptor Tocriset™ .

Biochem/physiol Actions

Excitotoxic amino acid. Prototypic agonist at the NMDA-type glutamate receptor that regulates ion channels; important in long-term potentiation, ischemia, and epilepsy.

storage

Room temperature

References

[1] watkins jc, jane de. the glutamate story. br j pharmacol. 2006 jan;147 suppl 1:s100-8.
[2] lafon-cazal m, pietri s, culcasi m, bockaert j. nmda-dependent superoxide production and neurotoxicity. nature. 1993 aug 5;364(6437):535-7.

N-Methyl-D-aspartic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-Methyl-D-aspartic acid Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alabiochem Tech.Co., Ltd.
Tel
0512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
995
Advantage
59
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Shanghai Qiude Biochemical Engineering Co., Ltd
Tel
021-37285021 13472570865;
Fax
86-021-51714507
Email
info@pure-chiral.com
Country
China
ProdList
288
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5700
Advantage
66
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4647
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4941
Advantage
60
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
ShenZhen InnoSyn Biotech Co.,Ltd
Tel
0755-28351685 18503098468
Fax
+86-755-28466854
Email
innosyn@163.com
Country
China
ProdList
600
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
China Nobel Chem Co., Limited
Tel
+86(0)21 60484900
Fax
+86(0)21 60484900
Country
China
ProdList
764
Advantage
50
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9906
Advantage
55
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3750
Advantage
55
TargetMol Chemicals Inc.
Tel
021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7934
Advantage
58
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8073
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3993
Advantage
60
HangZhou YuHao Chemical Technology Co., Ltd.
Tel
0571-82693216
Fax
0571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
2031
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16687
Advantage
50
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2989
Advantage
60
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
Nanjing Derno Pharmaceutical Technology Co., Ltd.
Tel
025-86957866 13952093866
Fax
025-68661287
Email
sales@dernopharm.com
Country
China
ProdList
924
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9972
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Quzhou Rundong Chemical (Technology) Co.
Tel
0570-8789886 18892685668
Fax
0570-8789985
Email
info@rundongchemical.com
Country
China
ProdList
3989
Advantage
60
Beijing NuoqiYa Biotechnology Co., Ltd.
Tel
4000-819-385 010-62329685 13718666987
Fax
010-62340519
Country
China
ProdList
1971
Advantage
55
Shanghai GL Peptide Ltd.
Tel
+86-21-61263310; 13764994101 13764994101
Fax
021-61263399
Email
fisherwang@glschina.com
Country
China
ProdList
8457
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862,442785678,326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9638
Advantage
58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3868
Advantage
58
More
Less

View Lastest Price from N-Methyl-D-aspartic acid manufacturers

Hebei Dangtong Import and export Co LTD
Product
N-Methyl-D-aspartic acid 6384-92-5
Price
US $3288.00-2680.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-09-15
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
N-Me-D-Asp 6384-92-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-04-13
Wuhan Cell Pharmaceutical Co., Ltd
Product
N-Methyl-D-aspartic acid 6384-92-5
Price
US $1.00-9.90/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2023-04-11

6384-92-5, N-Methyl-D-aspartic acidRelated Search:


  • N-METHYL-D-ASPARAGINIC ACID
  • N-METHYL-D-ASPARTIC ACID
  • N-METHYL-D-ASPARTIC ACID HYDROCHLORIDE
  • N-ME-D-ASPARTIC ACID
  • N-ME-D-ASP-OH
  • N-ME-D-ASP-OH HCL
  • NMDA
  • H-D-MEASP-OH
  • H-D-MEASP-OH HCL
  • [R]-2-[METHYLAMINO]SUCCINIC ACID
  • N-ALPHA-METHYL-D-ASPARTIC ACID
  • N-ALPHA-METHYL-D-ASPARTIC ACID HYDROCHLORIDE
  • N-Methyl D-artic acid.
  • (2R)-2-methylaminobutanedioic acid
  • (R)-2-(Methylamino)butanedioic acid
  • N-Methyl-D-Asp-OH
  • N-Methyl-D-aspartic acid,98%
  • N-Methyl-D-aspartic acid,(R)-2-(Methylamino)succinic acid, NMDA
  • N-Methyl-D-aspartic Acid Hydrate
  • N-Methyl D- aspartic acid (NMDA)
  • N-Methyl-D-aspartic acid, 98% 50MG
  • (R)-2-(Methylamino)succinic acid, NMDA
  • N-Methyl-D-aspartic Acid&nbsp
  • D-Aspartic acid,N-Methyl-
  • N-Methyl-D-aspartic acid SynonyMs (R)-2-(MethylaMino)succinic acid
  • NMDA (N-Methyl-D-aspartic acid)
  • N-Methyl-d-Aspartic Acid, ≥97%
  • N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5 - Calbiochem
  • n-methylaspartate
  • n-methyl-d-aspartate
  • n-methyl-d-asparticaci
  • (2R)-2-(methylammonio)butanedioate
  • N-Methyl-D-aspartic acid hydrochloride98+%
  • N-Me-D-Asp
  • N-Methyl-D-aspartic acid/C5H9NO4
  • N-Methyl-D-asparticAcidHydrate&gt
  • -D-aspartic acid
  • N-Methyl-D-aspartic acid (NMDA)99%
  • methyl-D-aspartic acid
  • N-Methyl-D-aspartic acid USP/EP/BP
  • 6384-92-5
  • C5H9NO4xH2O
  • Modified Amino Acids
  • I - Z
  • BioChemical
  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • Glutamate
  • amino acids
  • Glutamate receptor
  • Pyridines
  • Inhibitors