2-Bromotoluene Property

Melting point:

-27 °C (lit.)

Boiling point:

58-60 °C/10 mmHg (lit.)

Density 

1.422 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.555(lit.)

Flash point:

174 °F

storage temp. 

2-8°C

form 

Liquid

Specific Gravity

1.422

color 

Clear colorless to light yellow

Water Solubility 

<0.1 g/100 mL at 15 ºC

Merck 

14,1439

BRN 

1904176

Dielectric constant

4.2800000000000002

Stability:

Stable. Incompatible with strong oxidizing agents.

CAS DataBase Reference

95-46-5(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1-bromo-2-methyl-(95-46-5)

EPA Substance Registry System

o-Bromotoluene (95-46-5)

Safety

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38

Safety Statements 

36/37/39-37/39-26

WGK Germany 

3

RTECS 

XS7965500

Hazard Note 

Harmful/Irritant

TSCA 

Yes

PackingGroup 

III

HS Code 

29036990

Hazardous Substances Data

95-46-5(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

2-Bromotoluene Chemical Properties,Usage,Production

Chemical Properties

liquid

Uses

2-Bromotoluene was used in the synthesis of (±)-isocomene. Suzuki coupling of 2-bromotoluene with phenylboronic acid using palladium nanoparticles supported on alumina-based oxides as catalyst has been reported. 2-Bromotoluene is used in manufacturing pharmaceuticals (especially for nonsteroidal antiinflammatory drugs; Meclofenamic acid, Mefenamic acid) and other organic compounds

General Description

Clear colorless to pale beige liquid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Bromotoluene reacts with strong oxidizing agents.

Fire Hazard

2-Bromotoluene is combustible.

Purification Methods

Fractionally distil it through an efficient column. It can be separated from its isomers by gas chromatography on a column of “Sil-o-cel” firebrick (30-40mesh, 80 parts) coated with 5% (20 parts) of ICI E301 con rubber with N2 carrier gas at 170o/atm and 100mL/minute and using a conductivity cell detector. [Cowley et al. J Chem Soc 1801 1959, Beilstein 5 H 304, 5 I 153, 5 II 234 5 III 704, 5 IV 825.]